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Analysis

1 / 49,175
1.2011518140抗真菌薬及び抗ウイルス薬を含む局所併用
JP - 23.06.2011
Int.Class A61K 31/4412
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
44Non-condensed pyridines; Hydrogenated derivatives thereof
4412having oxo groups directly attached to the heterocyclic ring
 Appl.No 2011504526 Applicant シプラ・リミテッド Inventor アマル　ルウルルア

関連の感染症及び/又は疾患の予防及び/又は治療に有用な、抗真菌薬及び抗ウイルス薬を含む医薬組成物、及びその製造方法を提供する。
【選択図】 なし

2.2016196501USE OF LISTERIA VACCINE VECTORS TO REVERSE VACCINE UNRESPONSIVENESS IN PARASITICALLY INFECTED INDIVIDUALS
JP - 24.11.2016
Int.Class A61K 35/74
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
66Microorganisms or materials therefrom
74Bacteria
 Appl.No 2016148300 Applicant TRUSTEES OF THE UNIV OF PENNSYLVANIA Inventor DONALD A HARN JR

PROBLEM TO BE SOLVED: To provide methods for inducing Th1 immune response in a subject of parasite infection for the functionalization of the vaccine for malaria, tubercular (TB), and HIV-1.

SOLUTION: The present invention relates to use of Listeria vaccine vector in a subject with persistent Th2 immune-response profile. The Listeria vaccine vector expresses and secretes an antigen fused to an additional immunogenic polypeptide or a signal sequence thereof, the antigen being an infection antigen. The invention further includes use of a booster vaccine for producing an additional agent due to induce Th1 immune response. The booster vaccine comprises a DNA vaccine encoding an antigen fused to an additional immunogenic polypeptide or a signal sequence thereof, a recombinant polypeptide comprising an antigen fused to an additional immunogenic polypeptide or a signal sequence thereof, a viral vector encoding an antigen fused to an additional immunogenic polypeptide or a signal sequence therefore live recombinant Listeria vaccine vector.

SELECTED DRAWING: Figure 16

COPYRIGHT: (C)2017,JPO&INPIT

3.2022524503経皮抗微生物叢製剤
JP - 06.05.2022
Int.Class A61P 17/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17Drugs for dermatological disorders
 Appl.No 2021552834 Applicant ホフマン・テクノロジーズ・エルエルシー Inventor ホフマン，スティーブン
本開示は、消毒剤、抗生物質、抗真菌薬、抗寄生蠕虫剤、抗ウイルス薬、又はＮＳＡＩＤを含有する経皮組成物に向けられる。
【選択図】 なし
4.2016065083METHODS FOR TREATING MALARIA, TUBERCULOSIS AND MAC DISEASES
JP - 28.04.2016
Int.Class A61K 31/4192
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
41having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
41921,2,3-Triazoles
 Appl.No 2015224136 Applicant CEMPRA PHARMACEUTICALS INC Inventor PRABHAVATHI B FERNANDES

PROBLEM TO BE SOLVED: To provide a method for treating sufferers of malaria, tuberculosis and MAC diseases by a compound effective against them, and a pharmaceutical formulation comprising the compound.

SOLUTION: The present invention provides a compound represented by the formula and a pharmaceutical formulation comprising a therapeutically effective amount of the compound, and a method for treating sufferers of malaria, tuberculosis and MAC diseases by administration of the formulation [R10 is H or the like; X is H; Y is OR7, R7 is a monosaccharide or the like; V is -C(O)- or the like; R11 is OH or the like; R12 and R13 are H, OH or the like; R14 is H, OH or the like; W is H, F, OH and the like].

SELECTED DRAWING: None

COPYRIGHT: (C)2016,JPO&INPIT

5.2013534468廃水からの生理活性化合物の改善
JP - 05.09.2013
Int.Class C02F 1/58
CCHEMISTRY; METALLURGY
02TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
FTREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
1Treatment of water, waste water, or sewage
58by removing specified dissolved compounds
 Appl.No 2013514416 Applicant モリーコープ　ミネラルズ　エルエルシー Inventor バーバ、ジョン　エル．

本発明は、希土類固定剤を用いて、様々な流れから１つ以上の選択された標的物質、とりわけ生理活性化合物汚染物質を除去することに関する。

6.2018513873ベクターとしてセンダイウイルスを用いた抗結核菌ワクチン
JP - 31.05.2018
Int.Class A61K 48/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
48Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
 Appl.No 2017555692 Applicant 上▲海▼市公共▲衛▼生▲臨▼床中心 Inventor 范　小勇

ヒト型結核菌免疫優性抗原を発現する組換えセンダイウイルスベクターワクチンを提供する。このワクチンは、治療性と予防性の抗結核ワクチンとして使用することができる。

7.2021522257経口酵母ベータグルカンを用いる低免疫原性抗原特異的ワクチンの免疫原性強化方法
JP - 30.08.2021
Int.Class A61K 39/39
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
39Medicinal preparations containing antigens or antibodies
39characterised by the immunostimulating additives, e.g. chemical adjuvants
 Appl.No 2020559560 Applicant メモリアル　スローン－ケタリング　キャンサー　センター Inventor チュン　ナイ－コン

本開示は、低免疫原性抗原特異的ワクチンの免疫原性を強化する方法とともに、その必要がある対象動物で腸管微生物叢の多様化を促進する方法を提供し、前記方法は、酵母に由来するベータグルカン抽出物の有効量を対象動物に投与する工程を含む。前記方法の実施で使用されるキットもまた提供される。
【選択図】なし

8.2024019424METHODS OF ENHANCING IMMUNOGENICITY OF POORLY IMMUNOGENIC ANTIGEN-SPECIFIC VACCINES USING ORAL YEAST BETA-GLUCANS
JP - 09.02.2024
Int.Class A61K 31/716
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
716Glucans
 Appl.No 2023206230 Applicant MEMORIAL SLOAN-KETTERING CANCER CENTER Inventor CHEUNG NAI-KONG

PROBLEM TO BE SOLVED: To provide a method for enhancing immunogenicity of a poorly immunogenic antigen-specific vaccine as well as a method for promoting diversification of gut microbiome in a subject animal in need thereof.

SOLUTION: A method comprises administering to a subject animal an effective amount of a beta-glucan extract derived from yeast. There is also provided a kit for use in practicing the method.

SELECTED DRAWING: None

COPYRIGHT: (C)2024,JPO&INPIT

9.2009001493DNA VACCINE COMPOSITION
JP - 08.01.2009
Int.Class A61K 48/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
48Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
 Appl.No 2005280379 Applicant NATIONA HOSPITAL ORGANIZATION Inventor OKADA MASAMORI

PROBLEM TO BE SOLVED: To provide a medicinal composition which is effective for treating or preventing various diseases (infectious diseases, cancer diseases, neurodegenerative diseases, allergic diseases, autoimmune diseases, and the like) and contains a virus envelop vector and a DNA vaccine sealed in the virus envelop vector as active ingredients, and to provide a method for producing the same.

SOLUTION: A DNA vaccine (Hsp65 DNA and IL-12 DNA) effective as a tuberculosis vaccine has been sealed in a Sendai virus envelop vector and then administered in a model mouse to determine whether to exhibit an effect for preventing and treating tubercule bacilli infection. Consequently, it has been found that the effect of the DNA vaccine is reinforced by sealing the DNA vaccine in the virus envelop vector.

COPYRIGHT: (C)2009,JPO&INPIT

10.WO/2004/067040GENE VACCINE AGAINST INTRACELLULAR PARASITE
WO - 12.08.2004
Int.Class C07K 14/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
 Appl.No PCT/JP2004/000975 Applicant KYUSHU TLO COMPANY, LIMITED Inventor HIMENO, Kunihiro
It is intended to provide a fused DNA vaccine which is prepared by constructing a fused gene (a fused DNA) of a gene originating in an intracellular protozoa parasite (for example, tubercle bacillus, malaria parasite, toxoplasma, etc.) with a ubiquitin gene. Using the gene vaccine to each infection host, a ubiquitinated pathogen antigen (i.e., a gene product) is processed with a proteasome and thus CD8+T cells specific to the pathogen are strongly induced. Namely, it is intended to provide a gene vaccine characterized by containing a gene consisting of a gene originating in an intracellular protozoa parasite and a ubiquitin gene bonded thereto.
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