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PA/bayardo

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1 / 8
1.050637IMPLANTES Y MICROESFERAS DE LIBERACION PROLONGADA DE FARMACOS DE USO OFTALMICO Y METODOS PARA PREPARARLOS
AR - 08.11.2006
Int.Class A61K 9/14
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
9Medicinal preparations characterised by special physical form
14Particulate form, e.g. powders
 Appl.No P050103761 Applicant JIMENEZ BAYARDO, ARTURO Inventor HAU, JUAN DE DIOS QUINTANA
La presente está relacionada con un nuevo complejo sólido, insoluble en un ambiente acuoso y en su forma sca es útil para el dearrollo de nuevos sistemas de liberación prolongada de fármacos para uso oftálmico y un método parapreparar dicho complejo. El complejo etá formulado a base de una solución viscoelástica derivada de HA (Biovisc), un fármaco terapéuticamente aceptable como un esteroide, quinolona, antiinflamatorio no esteroideo, inmunosupresor o droga que sea compatible y quitosán, todos ellos conjugados en tal forma para producir matrices de polímeros biodegradables para el tratamiento de padecimientos oculares y un método para preparar dicha matrices. La presente refiere también a micoesferas y un procedimiento para la fabricación de las mismas utilizando los mismos materiales originales en donde el principio terapéutico es un esteroide, quinolona, antiinflamatorio no esteroideo, inmunosupresor o droga que sea compatible y estable con el sistema descrito.
2.PA/a/1997/001946SOLUCION OFTALMICA TRANSPORTADORA
MX - 01.04.1998
Int.Class A61K 31/24
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
31Medicinal preparations containing organic active ingredients
21Esters, e.g. nitroglycerine, selenocyanates
215of carboxylic acids
235having an aromatic ring attached to a carboxyl group
24having an amino or nitro group
 Appl.No PA/a/1997/001946 Applicant ARTURO JIMENEZ BAYARDO Inventor JOSE RUBEN TORNERO MONTAÑO
La presente invención se refiere a una composición de materia del tipo que se utiliza en el tratamiento de padecimientos oftálmicos y particularmente se refiere a una solución oftálmica transportadora a base de agentes tensioactivos, emulsificadores, bactericidas, antioxidantes, etc., que forman un transportador que envuelve o enmascara a un ingrediente activo tal como diclofenaco sódico u otros agentes antibióticos como la tobramicina, la gentamicina o el sulfato de timolol, con el objeto de evitar las molestias causadas por la aplicación tópica de los mencionados ingredientes activos, tales como dolor, ardor, irritación y otras molestias para el usuario.
3.MX/a/2007/012054PAZUFLOXACIN OPHTHALMIC FORMULATION
MX - 13.05.2009
Int.Class A61K 31/47
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
47Quinolines; Isoquinolines
 Appl.No MX/a/2007/012054 Applicant ARTURO JIMENEZ BAYARDO Inventor JOSE RUBEN TORNERO MONTAÑO
Described is a novel ophthalmic product, which is topically applied and which formulation is based on pazufloxacin as active ingredient;the invention is prescribed in infectious processes of the palpebral and bulbar conjuntiva, cornea and anterior eye segment, in chronic anterior uveitis, corneal damage and as a prophylactic treatment of post-surgical inflammation and infection.
4.2007001894FORMULACION OFTALMICA TOPICA QUE COMPRENDE: 0,1% DE DEXAMETASONA, 0,3% DE CLORHIDRATO DE CIPROFLOXACINO, CLORURO DE SODIO, 6% DE HIDROXIPROPIL-BETA-CICLODEXTRINA, 0,15% DE SULFATO DE SODIO, 0,05% DE EDETATO DISODICO, 0,022% DE CLORURO DE BENZALCONIO AL 50% Y 0,100ML/100ML DE POLISORBATO 80; UTIL PARA TRATAR INFECCIONES OCULARES.
CL - 04.01.2008
Int.Class A61K 31/573
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
31Medicinal preparations containing organic active ingredients
56Compounds containing cyclopentahydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
57substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
573substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
 Appl.No 2007001894 Applicant ARTURO JIMENEZ BAYARDO Inventor
Formulación oftálmica para administración vía tópica que comprende dexametasona base micronizada, clorhidrato de ciprofloxacino, cloruro de sodio, hidroxipropilbetaciclodextrinas, sulfato de sodio, edetato disódico, cloruro de benzalconio y polisorbato 80.
5.2003228126Method of preparing an aqueous solution of cyclosporin-a and resulting aqueous solution
AU - 14.08.2003
Int.Class A61K 38/13
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
38Medicinal preparations containing peptides
04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
12Cyclic peptides
13Cyclosporins
 Appl.No 2003228126 Applicant JIMENEZ BAYARDO, Arturo Inventor Bayza Duran, Leopoldo M.
The invention relates to a method of preparing a topically-applied pharmaceutical ophthalmic solution of cyclosporin-A in an aqueous solution for the treatment of different ocular ailments. The inventive method comprises a first phase consisting in preparing an ophthalmic carrier solution and a second phase consisting in solubilising the cyclosporin-A. According to the invention, the solutions obtained in the first and second phases are mixed while being agitated at a speed of 500 to 550 rpm in order to produce an aqueous solution of cyclosporin-A which is effective for the treatment of ocular disorders. The invention also relates to the novel aqueous solution of cyclosporin-A obtained using the above-mentioned method, which offers improved effectiveness, safety and performance in respect of the topical application thereof and which improves a patient's tolerance to the treatment.
6.WO/2004/096261METHOD OF PREPARING AN AQUEOUS SOLUTION OF CYCLOSPORIN-A AND RESULTING AQUEOUS SOLUTION
WO - 11.11.2004
Int.Class A61K 9/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
9Medicinal preparations characterised by special physical form
 Appl.No PCT/MX2003/000040 Applicant JIMENEZ BAYARDO, Arturo Inventor JIMENEZ BAYARDO, Arturo
The invention relates to a method of preparing a topically-applied pharmaceutical ophthalmic solution of cyclosporin-A in an aqueous solution for the treatment of different ocular ailments. The inventive method comprises a first phase consisting in preparing an ophthalmic carrier solution and a second phase consisting in solubilising the cyclosporin-A. According to the invention, the solutions obtained in the first and second phases are mixed while being agitated at a speed of 500 to 550 rpm in order to produce an aqueous solution of cyclosporin-A which is effective for the treatment of ocular disorders. The invention also relates to the novel aqueous solution of cyclosporin-A obtained using the above-mentioned method, which offers improved effectiveness, safety and performance in respect of the topical application thereof and which improves a patient's tolerance to the treatment.
7.2008-0347SOLUCION OFTALMICA DE CIPROFLOXACINA Y DEXAMETASONA
PE - 11.04.2008
Int.Class A61K 31/496
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
 Appl.No 2007000833 Applicant ARTURO JIMENEZ BAYARDO Inventor JUAN DE DIOS QUINTANA HAU
SE REFIERE A UNA COMPOSICION FARMACEUTICA OFTALMICA EN SOLUCION PARA APLICACION TOPICA, QUE COMPRENDE: A) DEXAMETASONA MICRONIZADA APROXIMADAMENTE 0,1%; B) CLORHIDRATO DE CIPROFLOXACINO MONOHIDRATADO APROXIMADAMENTE AL 0,3%; C) CLORURO DE SODIO EN CANTIDAD SUFICIENTE PARA OBTENER 250-350mOsm/K; D) HIDROXIPROPILBETACICLODEXTRINAS AL 6%, SULFATO DE SODIO, EDETATO SODICO, CLORURO DE BENZALCONIO POLISORBATO 80 COMO SURFACTANTE NO IONICO. DICHA COMPOSICION ES UTIL PARA EL TRATAMIENTO DE PADECIMIENTOS OCULARES CAUSADOS POR BACTERIAS Y HONGOS
8.WO/2008/002117OPHTHALMIC SOLUTION OF CIPROFLOXACIN AND DEXAMETHASONE
WO - 03.01.2008
Int.Class A61K 31/496
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
 Appl.No PCT/MX2006/000062 Applicant JIMENEZ BAYARDO, Arturo Inventor QUINTANA HAU, Juan de Dios
The invention concerns a topically applied formulation which is administered ophthalmically and which contains ciprofloxacin and dexamethasone. The formulation of the present invention is a solution which has excellent physico-chemical stability and is characterized by its greater bioavailability in comparison with suspensions, the present invention then being a formulation in solution, and not in suspension, of ciprofloxacin and dexamethasone.
9.1990000606ELIMINACION DE LA CONIFICACION DE AGUA EN POZOS PRODUCTORES DE PETROLEO POR MEDIOS MECANICOS, TENDIENTES A RESTAURAR LA PERMEABILIZACION ORIGINAL, RELATIVA AL PETROLEO
EC - 01.10.1990
Int.Class E21B 43/00
EFIXED CONSTRUCTIONS
21EARTH OR ROCK DRILLING; MINING
BEARTH OR ROCK DRILLING; OBTAINING OIL, GAS, WATER, SOLUBLE OR MELTABLE MATERIALS OR A SLURRY OF MINERALS FROM WELLS
43Methods or apparatus for obtaining oil, gas, water, soluble or meltable materials or a slurry of minerals from wells
 Appl.No 1990000606 Applicant GRANDES TRAVEZ, BAYARDO Inventor GRANDES TRAVEZ, BAYARDO
Un método para eliminar la conificación del agua, que consiste en restaurar la permeabilidad relativa al petróleo original, inyectando grandes volúmenes de un fluido incompatible con el agua y compatible con el crudo. Debiendo ser estos volúmenes desde 20 barriles por pie hasta 500 barriles o más por pie perforado, de tal forma que el agua del cono que se encuentra pegada a la pared del pozo y que está conectada hidráulicamente con el acuífero sea desplazada decenas de pies adentro del yacimiento, rompiéndose así definitivamente la continuidad hidráulica del cono acuífero.
10.JL/a/2002/000046INTRAVITREOUS INJECTABLE SOLUTION FOR THE TREATMENT OF VITREOUS HEMORRHAGES
MX - 26.08.2004
Int.Class A61K 9/08
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
9Medicinal preparations characterised by special physical form
08Solutions
 Appl.No JL/a/2002/000046 Applicant ARTURO JIMENEZ BAYARDO. Inventor ARTURO JIMENEZ BAYARDO.
The present invention relates to an ophthalmic solution for clarifying vitreous hemorrhages. Specifically, it is about an intraocular injectable solution, pharmaceutically acceptable for the treatment of vitreous hemorrhage, by which the re-absorption of said hemorrhages is promoted. With this is possible the vitreous hemorrhage clarifying in a significantly short period of time to allow the prompt diagnosis of the injury and the repair of the damage caused by the hemorrhage in the vitreous body. The ophthalmic solution of the present invention is injected at least once to the patient in a therapeutically effective dose to obtain the desired result.
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