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IC:G01N33/48

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Analysis

1 / 74,427
1.WO/2025/137774METHOD OF GENERATING AND SCREENING PEPTIDE APTAMER LIBRARIES FROM NATURALLY OCCURRING PROTEINS
WO - 03.07.2025
Int.Class G16B 40/10
GPHYSICS
16INFORMATION AND COMMUNICATION TECHNOLOGY SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
40ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
10Signal processing, e.g. from mass spectrometry or from PCR
 Appl.No PCT/CA2024/051737 Applicant MARSHALL, John G. Inventor MARSHALL, John G.
Provided herein are methods of making a peptide aptamer library from naturally occurring proteins and/or peptides. The peptide aptamer library can be generated from immunoglobulins, B cell receptors and/or T cell receptors of a host animal. Biological samples such as cells and biofluids can be used as a library of peptide aptamers. Also provided herein are methods to identify peptide aptamers that bind a target using the peptide aptamer library generated by the methods disclosed herein.
2.WO/2025/143714DIAGNOSTIC KIT FOR BOVINE DIARRHEA-CAUSING VIRUS
WO - 03.07.2025
Int.Class C07K 14/005
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
005from viruses
 Appl.No PCT/KR2024/020949 Applicant BOREDA BIOTECH Inventor CHOI, Dong Ok
The present invention relates to a diagnostic kit for bovine viral diarrhea virus (BVDV), which enables rapid on-site identification and diagnosis of BVDV1 and BVDV2, which are genotypes of the BVD virus that are pathogens causing bovine diarrhea, within a short time of approximately 15 minutes.
3.WO/2025/141779METHOD FOR DETERMINING PLASMA FRACTIONATION CONDITIONS, PLASMA FRACTIONATION DEVICE, AND DNA EXTRACTION DEVICE EQUIPPED WITH SAME
WO - 03.07.2025
Int.Class G01N 33/48
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
 Appl.No PCT/JP2023/046974 Applicant HITACHI HIGH-TECH CORPORATION Inventor MATSUMOTO Yuki
This method for determining fractionation conditions for plasma 105 includes: a step for measuring a blood sample by means of a blood condition confirmation unit; a step for obtaining a converted number of elapsed days from the blood collection date of the blood sample on the basis of the measurement results; a step for calculating the amount of gDNA in the blood sample on the basis of the converted number of elapsed days; and a step for determining the plasma fractionation conditions on the basis of the calculated amount of gDNA. The present invention thus provides a method for determining plasma fractionation conditions, a plasma fractionation device, and a DNA extraction device equipped with the same, with which it is possible to perform a plasma fractionation step under more appropriate conditions than in the past.
4.WO/2025/142889DEVICE FOR CLASSIFYING EXTRACELLULAR VESICLES, AND IN VITRO METHOD FOR CLASSIFYING EXTRACELLULAR VESICLES AND DETECTING OR ANALYZING PROTEINS CONTAINED IN EXTRACELLULAR VESICLES
WO - 03.07.2025
Int.Class G01N 33/68
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68involving proteins, peptides or amino acids
 Appl.No PCT/JP2024/045586 Applicant BIOPHENOMA INC. Inventor SHIGA Hatsuki
The present disclosure relates to a device for classifying extracellular vesicles. The present disclosure also relates to an in vitro method for classifying extracellular vesicles and detecting or analyzing proteins contained in extracellular vesicles.
5.WO/2025/144254RAPID DIAGNOSTIC KIT USING PHAGE RECEPTOR BINDING PROTEINS IN LATERAL FLOW ASSAY SYSTEMS FOR BACTERIAL IDENTIFICATION
WO - 03.07.2025
Int.Class B01L 3/00
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
3Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
 Appl.No PCT/TR2024/051424 Applicant YILDIZ TEKNIK UNIVERSITESI DONER SERMAYE ISLETME MUD Inventor TAMER, Ugur
Relates to a test method and test kit for the identification of the type, species or strain of bacteria contained in a sample, where the capture probe contains a bacteriophage receptor binding protein specific for the bacteria to be tested. The receptor binding protein can be labelled in conjugated form with gold nanoparticles.
6.WO/2025/137775METHOD OF GENERATING AND SCREENING SYNTHETIC PEPTIDE APTAMER LIBRARIES
WO - 03.07.2025
Int.Class C40B 30/04
CCHEMISTRY; METALLURGY
40COMBINATORIAL TECHNOLOGY
BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
30Methods of screening libraries
04by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
 Appl.No PCT/CA2024/051738 Applicant MARSHALL, John G. Inventor MARSHALL, John G.
Provided herein are methods of making a peptide aptamer library of partially random peptide aptamers. The peptide aptamer library can be designed with tryptic and chymotryptic sites spaced to create domains. In each domain, a defined subset of amino acids are randomly ordered alongside invariant amino acids. Also provided herein are methods to identify peptide aptamers that bind a target using the peptide aptamer library disclosed herein.
7.WO/2025/138090BLOOD CELL ANALYZER AND BLOOD CELL ANALYSIS METHOD
WO - 03.07.2025
Int.Class G01N 15/01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
15Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
01specially adapted for biological cells, e.g. blood cells
 Appl.No PCT/CN2023/143179 Applicant SHENZHEN MINDRAY ANIMAL MEDICAL TECHNOLOGY CO., LTD. Inventor KONG, Fangang
The present application relates to a blood cell analyzer and a blood cell analysis method. One part of a suctioned blood sample to be detected, a diluent and a fluorescent coloring agent are mixed in a first reaction tank to prepare a first measurement sample, and first optical information generated by particles in the first measurement sample when said particles are irradiated by light is obtained; the other part of said blood sample and a hemolytic agent are mixed in a second reaction tank to prepare a second measurement sample, and colorimetric method optical information of the second measurement sample is obtained; a reticulocyte detection result, a platelet detection result, an erythrocyte detection result and a first leukocyte detection result of said blood sample are obtained on the basis of the first optical information, the first leukocyte detection result at least comprising a lymphocyte percentage, a monocyte percentage and a granulocyte percentage; and the hemoglobin concentration of said blood sample is determined on the basis of the colorimetric method optical information. The present application allows for reduction of the reagent costs required for obtaining the detection result of a blood sample to be detected.
8.WO/2025/140985ENGINEERED HEART TISSUE MEASURING PLATFORM, SOFTWARE, AND COMPONENTS FOR THE SAME
WO - 03.07.2025
Int.Class G01N 33/483
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
483Physical analysis of biological material
 Appl.No PCT/EP2024/087943 Applicant DINABIOS AG Inventor GRUNERT, Marcel
Disclosed herein are embodiments of tissue measurement platforms, software, and components for the same. In at least one embodiment, a measurement chamber comprises: a sample tray, one or more light sources, and one or more cameras configured to capture images and/or video of a plurality of tissue samples when loaded onto the sample tray. In at least one embodiment, the measurement chamber is operatively coupled to an evaluation unit and is configured to evaluate the plurality of tissue samples in parallel.
9.WO/2025/137784IN VITRO METHOD FOR THE DIAGNOSIS AND PROGNOSIS OF ALCOHOL-RELATED LIVER DISEASE
WO - 03.07.2025
Int.Class G01N 30/02
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
30Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography
02Column chromatography
 Appl.No PCT/CL2023/050146 Applicant PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE Inventor ALLENDE SANZANA, Fidel Alejandro
The present invention discloses an in vitro method for the detection or diagnosis of alcohol-related liver disease using biomarkers. The method is based on measuring bile acids (BAs) contained in extracellular vesicles (EVs).
10.WO/2025/140619MULTISPECIFIC ANTIBODY CONTAINING CCR8 ANTIGEN BINDING DOMAIN
WO - 03.07.2025
Int.Class C07K 16/28
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
 Appl.No PCT/CN2024/143352 Applicant SUZHOU ZELGEN BIOPHARMACEUTICALS CO., LTD. Inventor LV, Binhua
Provided are a multispecific antibody and the use thereof. Specifically, provided is a multispecific antibody, which contains a first targeting domain that targets a chemokine (C-C motif) receptor 8 (CCR8) molecule highly expressed on the surface of a tumor-infiltrating regulatory T cell (Treg), and a second targeting domain that binds to VEGF and/or a third targeting domain that binds to PD-L1. Various functional domains of the CCR8-related multispecific antibody block a PD-1/PD-L1 immunosuppressive pathway, etc. by means of killing the tumor-infiltrating Treg, so that a T cell is activated, and the generation of a tumor vessel is inhibited. Therefore, the CCR8-related multispecific antibody can be used as an effective therapeutic agent for tumor treatment.
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