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Analysis

1.P20251434METHOD OF TREATING CANCER USING IMMUNE CHECKPOINT INHIBITOR; ANTIBODY THAT BINDS TO PROGRAMMED DEATH-1 RECEPTOR (PD-1) OR PROGRAMMED DEATH LIGAND 1 (PD-L1)
HR 30.01.2026
Int.Class C07K 16/28
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
Appl.No P20251434T Applicant Bristol-Myers Squibb Company Inventor Demetrios Manekas
2.20260028661COMPOUNDS AND METHODS RELATING TO TESTING FOR LYSOSOMAL STORAGE DISORDERS
US 29.01.2026
Int.Class C12Q 1/34
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
34involving hydrolase
Appl.No 19174322 Applicant University of Washington through its Center for Commercialization Inventor Alexander Cherkassky

Provided are substrates and methods for detecting enzymatic activity of various lysosomal storage enzymes. The molecules may be used as substrates with improved solubility.

3.20260028669METHODS AND COMPOSITIONS FOR NUCLEIC ACID ANALYSIS
US 29.01.2026
Int.Class C12Q 1/6869
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
6869Methods for sequencing
Appl.No 19099917 Applicant CHAPTER DIAGNOSTICS, INC. Inventor Chunlin Wang

The present disclosure relates to compositions and methods for detection, identification, sequence analysis and quantification of biological organisms in a single amplification reaction. The disclosed method utilizes next-generation sequencing (NGS) to sequence amplified products. The present disclosure is also directed to kits containing primers specific to microbial and viral organisms, cancer, genetic disorders and forensics.

4.20260028614Isotachophoresis for Purification of Nucleic Acids
US 29.01.2026
Int.Class C12N 15/10
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
10Processes for the isolation, preparation or purification of DNA or RNA
Appl.No 19307653 Applicant Purigen Biosystems, Inc. Inventor Lewis A. Marshall

The present disclosure relates to fluidic systems and devices for processing, extracting, or purifying one or more analytes. These systems and devices can be used for processing samples and extracting nucleic acids, for example by isotachophoresis. In particular, the systems and related methods can allow for extraction of nucleic acids, including non-crosslinked nucleic acids, from samples such as tissue or cells. The systems and devices can also be used for multiplex parallel sample processing.

5.20260028641TRANSGENIC CORN EVENT MON95275
US 29.01.2026
Int.Class C12N 15/82
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
79Vectors or expression systems specially adapted for eukaryotic hosts
82for plant cells
Appl.No 19346280 Applicant Monsanto Technology LLC Inventor Sarah L. Brown

The invention provides a transgenic corn event MON95275, plants, plant cells, seeds, plant parts (including pollen, seed, and cells, and tissues corresponding to tassel, root, stalk, stem, leaf, cobb, and the like), progeny plants, commodity products comprising detectable amounts of corn event MON95275 DNA. The invention also provides polynucleotides specific for corn event MON95275 and methods for using and detecting corn event MON95275 DNA as well as plants, plant cells, seeds, plant parts, progeny plants, and commodity products comprising corn event MON95275. The invention also provides methods related to making and using corn event MON95275.

6.20260028683ASSAYS FOR FUNGAL INFECTION
US 29.01.2026
Int.Class C12Q 1/6895
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
6888for detection or identification of organisms
6895for plants, fungi or algae
Appl.No 19353138 Applicant Rutgers, The State University of New Jersey Inventor Steven Park

Methods and kits are described for testing for the presence or absence of any fungus in a sample. Examples of fungi that can be detected include, but are not limited to, those belonging to the genera Candida, Aspergillus and Pneumocystis. The methods include obtaining a sample suspected of containing fungal nucleic acid, including at least one universal region of fungal nucleic acid, and testing for the presence or absence in the sample of the at least one universal region of fungal nucleic acid. Samples may be biological or non-biological.

7.20260026457Petunia-Calibrachoa Variety SAKPXC039
US 29.01.2026
Int.Class A01H 6/82
AHUMAN NECESSITIES
01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
HNEW PLANTS OR PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
6Angiosperms, i.e. flowering plants, characterised by their botanic taxonomy
82Solanaceae, e.g. pepper, tobacco, potato, tomato or eggplant
Appl.No 18786518 Applicant Sakata Seed Corporation Inventor Moriya Kawashima

A petunia-calibrachoa plant designated SAKPXC039 is disclosed. Embodiments include the seeds of petunia-calibrachoa SAKPXC039, the plants of petunia-calibrachoa SAKPXC039, to plant parts of petunia-calibrachoa SAKPXC039, and methods for producing a plant produced by crossing petunia-calibrachoa SAKPXC039 with itself or with another variety. Embodiments include methods for producing a plant containing in its genetic material one or more genes or transgenes and the transgenic plants and plant parts produced by those methods. Embodiments also relate to varieties, breeding varieties, plant parts, and cells derived from petunia-calibrachoa SAKPXC039, methods for producing other lines or plant parts derived from petunia-calibrachoa SAKPXC039, and the plants, varieties, and their parts derived from use of those methods. Embodiments further include hybrid seeds, plants, and plant parts produced by crossing petunia-calibrachoa SAKPXC039 with another variety.

8.WO/2026/020369BREWING CONTROL METHOD, BREWING CONTROL APPARATUS, BREWING SYSTEM, ELECTRONIC DEVICE, AND COMPUTER STORAGE MEDIUM
WO 29.01.2026
Int.Class C12C 11/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
CBEER; PREPARATION OF BEER BY FERMENTATION; PREPARATION OF MALT FOR MAKING BEER; PREPARATION OF HOPS FOR MAKING BEER
11Fermentation processes for beer
Appl.No PCT/CN2024/107291 Applicant SIEMENS AKTIENGESELLSCHAFT Inventor LIU, Xin
A brewing control method includes: determining a target process control parameter corresponding to a type of a to-be-produced beer from a plurality of process control parameters; acquiring fermentation tank information of a target fermentation tank; determining a discharge path of the target fermentation tank based on the fermentation tank information; and controlling connection and disconnection of the discharge path based on the target process control parameter. According to this solution, the target process control parameter corresponding to the type of the to-be-produced beer is determined from the plurality of pre-stored process control parameters during beer brewing, thereby automatically controlling the connection and disconnection of the discharge path of the target fermentation tank based on the target process control parameter with higher accuracy and safety than manual control, and saving labor costs.
9.WO/2026/023774COMPOSITION FOR DIAGNOSING MYOCARDIAL INFARCTION AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING MYOCARDIAL INFARCTION
WO 29.01.2026
Int.Class C12Q 1/6883
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
6883for diseases caused by alterations of genetic material
Appl.No PCT/KR2024/097051 Applicant CATHOLIC KWANDONG UNIVERSITY INDUSTRY FOUNDATION Inventor KIM, Sang Woo
The present invention relates to a composition for diagnosing myocardial infarction, a diagnostic kit comprising same, a method for providing information for diagnosing myocardial infarction, and a pharmaceutical composition for preventing or treating myocardial infarction. The composition, kit, and method of the present invention use exosome markers miR-30c-1-3p, miR-149-3p, miR-206-3p, miR-486a-3p, miR-673-3p, miR-690-3p, miR-700-5p, miR-706, miR-744-5p, miR-871-3p, miR-874-5p, miR-1247-5p, miR-1306-5p, miR-3057-3p, miR-3086-5p, miR-3470a, miR-3470b, miR-3968, miR-5107-5p, and miR-7225-5p, and thus are expected to be effective in diagnosis for the prevention of myocardial infarction and useful in developing therapeutic substances.
10.WO/2026/024929DISEASE DIAGNOSIS AND MONITORING USING MICROBIAL RIBOSOMAL RNA PRESENT IN EXTRACELLULAR VESICLES
WO 29.01.2026
Int.Class C12N 15/10
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
10Processes for the isolation, preparation or purification of DNA or RNA
Appl.No PCT/US2025/039021 Applicant GUSTO GLOBAL, LLC Inventor VAN DER LELIE, Daniel
Methods are provided for detecting disease in liquid biopsy samples by identifying microbial rRNA. The methods include isolating nucleic acids from extracellular vesicles, treating the nucleic acids with DNase to remove DNA including human cfDNA, mcfDNA, and contaminating microbial DNA, and then amplifying a region of a microbial phylogenetic rRNA. To further reduce contaminating DNA, the amplifying step can include reverse transcription to translate the phylogenetic region into cDNA and extend the cDNA ends with a T7 promoter and sequencing adaptors. The translated region is amplified with primers to the extended ends of the cDNA and sequenced. The resulting phylogenetic microbial sequences are useful for diagnosis and monitoring of diseases including cancer. The method can further include amplification of other human or bacterial DNA or RNA sequences to augment disease diagnosis. The method results in a very low contribution of contaminating microbial DNA and RNA to the overall microbial signature.