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IC:C12M

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1 / 29,257
1.WO/2026/022647DEVICE FOR MONITORING THE GROWTH OF A THREE-DIMENSIONAL CELL CLUSTER AND METHOD FOR MANUFACTURING THE SAME
WO - 29.01.2026
Int.Class C12M 1/34
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
34Measuring or testing with condition measuring or sensing means, e.g. colony counters
 Appl.No PCT/IB2025/057288 Applicant FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA Inventor ZIAJA, Kamil
Device (1), and method for manufacturing the same, for detecting the growth of a three-dimensional cell cluster (C), comprising: a substrate (2) having a support surface (21); a plurality of electrodes (3) arranged according to a predetermined spatial distribution, for detecting an electrical potential in the presence of a three-dimensional cell cluster (C); a plurality of three-dimensional scaffolds (4), comprising at least a first scaffold (41), arranged at a respective measuring electrode (31), and at least a second scaffold (42), arranged at a respective reference electrode (32), wherein the at least one first scaffold (41) has a proliferation conformation, adapted to promote the growth of the three-dimensional cell cluster (C), and the at least one second scaffold (42) has an inhibition conformation adapted to prevent the growth of the three- dimensional cell cluster (C).
2.WO/2026/023232V-SHAPED CULTURE VESSEL
WO - 29.01.2026
Int.Class C12M 1/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
 Appl.No PCT/JP2025/019031 Applicant PHYTOLIPID TECHNOLOGIES CO., LTD. Inventor SATO, Ryoichi
In order to culture algae while suppressing the amount of energy that is input, the present invention provides a culture vessel for culturing algae, the culture vessel being characterized by having a structure in which the vertical cross section of the culture vessel is V-shaped and the horizontal cross section of the culture vessel is rectangular.
3.WO/2026/021626CONTACT PLATE
WO - 29.01.2026
Int.Class C12M 1/22
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
22Petri dishes
 Appl.No PCT/DE2025/100478 Applicant PHARMAMEDIA DR. MÜLLER GMBH Inventor EIKMANNS, Ulrich
The invention relates to a contact plate comprising a dish (1) for receiving a nutrient medium, the dish having a base and an inner rim (2) delimiting the base. Furthermore, a lid (8) is provided which acts as an aerobic and/or anaerobic closure, can be slid over the inner rim (2) by means of a lid rim (9), and, optionally, can be locked with respect to the dish (1). The dish (1) has an outer rim (5) running coaxially around and at a distance from the inner rim (2), wherein an annular space (6) is formed between the inner rim (2) and the outer rim (5), which annular space is intended for inserting and optionally locking the lid rim (9), and wherein at least one groove (7) extending along at least portions of the circumference, or radially and/or axially oriented grooves, is/are formed on or in the base of the annular space (6), which groove(s) is/are intended for receiving a liquid, preferably in the form of condensation water, running over the inner rim (2) and/or the lid (8) and into the annular space (6).
4.WO/2026/024761SCALABLE CLOSED-LOOP BIO-MANUFACTURING OF TUMOR MODELS OR OTHER VOLUMETRIC BIOLOGICAL SAMPLES
WO - 29.01.2026
Int.Class B01L 3/00
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
3Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
 Appl.No PCT/US2025/038723 Applicant THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS Inventor KING, William, P.
Systems and methods are provided for automated incubation of large numbers of tumor organoids or other volumetric biological samples cultured from cells or other tissues. Label-free, non-destructive imaging of the samples is performed quickly and at high temporal resolution (e.g., once per day or more), allowing interventions (like the addition or subtraction of substances like water, glucose, buffers, or pharmaceuticals) to be applied to each sample based on the images, facilitating closed-loop per-sample control of sample growth. This can lead to improved incubation outcomes, like increased rates of generation of live samples and control of sample size or other sample properties. Image and other incubation data obtained via such automated incubation processes can be used to train machine learning models to plan interventions for the samples, further increasing incubation success rates and allowing for the incubation of rare and/or novel samples, for which reliable incubation protocols do not yet exist.
5.WO/2026/022367A SYSTEM AND A METHOD FOR THE ANALYSIS OF IN-VITRO CONTRACTILE CELL TISSUE
WO - 29.01.2026
Int.Class C12M 3/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
3Tissue, human, animal or plant cell, or virus culture apparatus
 Appl.No PCT/EP2025/071508 Applicant SOPHION BIOSCIENCE A/S Inventor HERMANN, Miguel
A system (1) for analysis of in-vitro contractile cell tissue well plates. The well plates are received on a base (3) comprising at least two defined positions (4-12). A processing structure (15) is configured for carrying out an experiment with respect to each well plate held by the defined positions, and an electronic controller (19) is configured to control the processing structure and comprising at least one preprogrammed procedure defining at least one procedural step of the experiment. To provide improved conditions for multiple users or different simultaneous cell experiments, the controller is configured to determine a parameter of a well plate, to associate the parameter with a procedural step, and to carry out the procedural steps as part of the experiment with respect to the active well plate.
6.WO/2026/022502METHOD FOR PRODUCING IRON OR STEEL AND ASSOCIATED PLANT
WO - 29.01.2026
Int.Class C21B 7/00
CCHEMISTRY; METALLURGY
21METALLURGY OF IRON
BMANUFACTURE OF IRON OR STEEL
7Blast furnaces
 Appl.No PCT/IB2024/057085 Applicant ARCELORMITTAL Inventor MERTENS, Bruno
The present invention concerns a method and a plant complex for producing iron or steel.
7.WO/2026/022007CELL CULTURE CONTAINER OPERATING DEVICE FOR SECURELY DETACHABLY RECEIVING A CELL CULTURE CONTAINER DURING CELL CULTURE MANAGEMENT
WO - 29.01.2026
Int.Class C12M 1/24
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
24tube or bottle type
 Appl.No PCT/EP2025/070574 Applicant HAMILTON BONADUZ AG Inventor FRANZ, Fabian
A cell culture container operating device (748) for a cell culture management apparatus (10) comprises: - a cell culture container carrier (749) having a receiving device (729) designed to receive a cell culture container (12), - a connection structure (62) for the fluid-transferring connection of a cell culture container (12), wherein at least one component from the cell culture container carrier (749) and the connection structure (62) can be moved towards and away from the respective other component, - a clamping apparatus (732), wherein at least one structural part from the clamping apparatus (732) and the receiving device (729) can be moved towards and away from the respective other structural part, and - a common movement drive (740) both for driving the at least one component from the cell culture container carrier (749) and the connection structure (62) and for driving the at least one structural part from the clamping apparatus (732) and the receiving device (729), wherein the movement drive (740) is coupled to each structural unit from the at least one component and the at least one structural part in such a way as to transmit drive force, and wherein the movement drive (740) is coupled to at least one structural unit from the at least one component and the at least one structural part as a structural unit (749) driven in a force-buffered manner in at least one buffer movement direction (BMD) with interposition of an energy store (760) for transmission purposes.
8.WO/2026/023535CELL CULTURE BODY PRODUCTION METHOD, CELL CULTURE MEMBER PRODUCTION METHOD, CELL CULTURE BODY, AND CELL CULTURE MEMBER
WO - 29.01.2026
Int.Class C12M 1/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
 Appl.No PCT/JP2025/025570 Applicant TOYO ROSHI KAISHA, LTD. Inventor TABATA Yasuhiko
A cell culture body production method for producing a cell culture body used for culturing cells, the method comprising a decellularization step of obtaining an extracellular matrix secreted from human-derived cells by decellularizing a culture substrate obtained by culturing the human-derived cells.
9.WO/2026/024900DEVICES AND METHODS ENABLING CELLS TO UNDERGO BOTH VISUAL AND MOLECULAR DIAGNOSTICS
WO - 29.01.2026
Int.Class C12M 3/06
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
3Tissue, human, animal or plant cell, or virus culture apparatus
06with filtration, ultrafiltration, inverse osmosis or dialysis means
 Appl.No PCT/US2025/038952 Applicant CORRAMEDICAL, INC. Inventor MOJICA, Wilfrido
Devices and methods that enable loose cells to undergo both visual and molecular diagnostics are disclosed herein. In an embodiment, a microfluidic chip includes an input area, a viewing area, an output area and a filter. The input area is configured to receive cells obtained from a patient. The viewing area is in fluid communication with the input area. The viewing area is configured to enable a user to view the cells received at the input area. The output area is in fluid communication with the input area and the viewing area such that fluid mixed with the cells can flow from the input area, through the viewing area, to the output area. The filter is located between the viewing area and the output area, the filter configured to allow the fluid mixed with the cells to flow into the output area while preventing at least some of the cells from flowing into the output area.
10.WO/2026/022678METHOD AND DEVICE FOR ISOLATING AND ENRICHING PATHOGENIC NUCLEIC ACIDS FROM BIOLOGICAL SAMPLES
WO - 29.01.2026
Int.Class C12N 15/10
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
10Processes for the isolation, preparation or purification of DNA or RNA
 Appl.No PCT/IB2025/057377 Applicant D-NOME PRIVATE LIMITED Inventor DEB, Sujoy
The present invention relates to a method for isolating and enriching pathogenic nucleic acids from a biological sample thereby reducing host nucleic acid contamination and enrich relative pathogenic DNA in the infectious disease sample and a device thereof. The method involves mixing pathogenic nucleic acid containing biological sample with a lysis buffer at a temperature between 25-35°C for partial or incomplete lysis of the sample; passing the lysed sample through a depth filter wherein the filter paper size ranges from 0.22 microns to 20 microns; passing an elution buffer by reverse plunging action and generating a vibration of 200 to 350 Hz with discontinuous pulse of 20-30 seconds for 2-5 minutes for eluting pathogenic nucleic acids into the elution buffer. The invention further provides a device for isolating and enriching pathogenic nucleic acids from a nucleic acid containing biological sample thereby reducing host nucleic acid contamination using said method.
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