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IC:C12M

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1 / 29,253
1.20260022325CELL MANUFACTURING ON AN AUTONOMOUS PLATFORM
US - 22.01.2026
Int.Class C12M 1/36
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
36including condition or time responsive control, e.g. automatically controlled fermentors
 Appl.No 19273771 Applicant Cellino Biotech, Inc. Inventor Marinna Madrid

A method for cell culture expansion and maintenance, comprising seeding, in a first cell culture cassette, a plurality of cell colonies adhered to a first surface of the first cell culture cassette; capturing, by an optical engine, time-series images of the plurality of cell colonies as the plurality of cell colonies expand; determining, by a platform manager, a subset of cell colonies to remove from the first surface based on the time-series images; removing, by the optical engine, the subset of cell colonies from the first surface; washing, by a fluid management system, the removed subset of cell colonies from the first cell culture cassette; repeating steps for one or more iterations; harvesting a set of remaining cell colonies from the first cell culture cassette; seeding the set of remaining cell colonies into a second cell culture cassette; repeating steps for additional iterations in the second cell culture cassette.

2.20260022332CHIMERIC SURFACES AND USES THEREOF
US - 22.01.2026
Int.Class C12N 5/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
 Appl.No 19116716 Applicant THE PENN STATE RESEARCH FOUNDATION Inventor Pak Kin Wong

The present disclosure provides chimeric surfaces. The chimeric surfaces may be thin films. In various embodiments, the thin films may be disposed on a substrate. Articles of manufacture may have one or more chimeric surfaces. Also disclosed are methods of making organoids from cancer cells and methods of determining whether a subject has cancer. The thin films may be formed from one or more siloxanes and one or more lubricants.

3.WO/2026/017915CAROTENOID PRODUCTION METHODS USING RACEWAY POND SYSTEMS
WO - 22.01.2026
Int.Class C12P 23/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
23Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
 Appl.No PCT/EP2025/070906 Applicant ALIMENTOS VENTURES GMBH Inventor JOVINE, Raffael
The invention relates to methods for producing carotenoids by culturing algae in land-based mariculture using a "hurry up and wait" approach in which growth rates are maximised upstream for maximum throughput and decreased quickly via intensive stressing before harvest.
4.20260022320CELL RETENTION APPARATUS WITH CONVECTIVE FLOW
US - 22.01.2026
Int.Class C12M 1/34
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
34Measuring or testing with condition measuring or sensing means, e.g. colony counters
 Appl.No 19275236 Applicant Board of Trustees of Michigan State University Inventor Brian P. JOHNSON

A cell retention apparatus with convective flow is provided. In another aspect, a microplate-based array of microfluidic wells has a heater or cooler which generates controllable temperature gradients within and/or between the wells, such as in an injection molded and/or disposable cell culture well plate. These gradients create convection currents within the well that generate flow or within connecting microchannels between wells. A further aspect induces controlled thermal convection currents within wells of a microtiter plate to drive fluid movement.

5.WO/2026/019334REAL-TIME BACTERIA DETECTION AND IDENTIFICATION DEVICE
WO - 22.01.2026
Int.Class C12Q 1/04
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
02involving viable microorganisms
04Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
 Appl.No PCT/PT2024/050027 Applicant UNIVERSIDADE DE COIMBRA Inventor MOTA LEITE MACHADO MARIZ, Marcos João
The present invention relates to a real-time bacteria detection and identification device (1) comprising a body, said body comprising: an inlet opening (2) and an outlet opening (3), configured for passage of a fluid; a central portion (4) located between the inlet opening (2) and the outlet opening (3), said central portion (4) being configured to allow the visualization of an at least one porous polymer-based matrix (5), said matrix (5) comprising at least one polymer, said polymer comprising at least one entrapped lysis compound, at least one immobilized bacteria attracting compound and at least one immobilized chromogenic substrate, wherein said immobilized chromogenic substrate of the polymer-based matrix (5) is configured to change its colour when contacted with a bacterium containing fluid.
6.WO/2026/016350CELL CULTURE DEVICE, MANUFACTURING METHOD THEREFOR AND CULTURE METHOD THEREOF
WO - 22.01.2026
Int.Class C12M 3/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
3Tissue, human, animal or plant cell, or virus culture apparatus
 Appl.No PCT/CN2024/132217 Applicant TSINGHUA UNIVERSITY Inventor PANG, Yuan
Provided are a cell culture device, a manufacturing method therefor and a culture method thereof. The cell culture device comprises a composite culture layer, the composite culture layer comprising: a culture through-hole layer, at least one vertically penetrating culture through hole being distributed in the culture through-hole layer; and an air-permeable microporous layer, the air-permeable microporous layer comprising at least one air-permeable portion, the surface of each air-permeable portion being provided with at least one micropore, and the material of the air-permeable portion being capable of allowing oxygen to pass through, wherein the air-permeable portions are in one-to-one correspondence with the culture through holes, and each air-permeable portion covers a port at one end of a corresponding culture through hole, so as to define, together with the corresponding culture through hole, a culture chamber, the micropores being located inside the culture chambers.
7.WO/2026/016920NUCLEIC ACID TEST CARTRIDGE AND NUCLEIC ACID TEST METHOD
WO - 22.01.2026
Int.Class C12M 1/34
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
34Measuring or testing with condition measuring or sensing means, e.g. colony counters
 Appl.No PCT/CN2025/107061 Applicant GUANGZHOU WONDFO BIOTECH CO., LTD. Inventor ZHU, Zhihua
A nucleic acid test cartridge and a nucleic acid test method. The cartridge is provided with a sample inlet and a sample chamber in communication with the sample inlet. A lysis chamber, an elution chamber, and a reaction chamber, which are sequentially in communication by means of a flow channel, are arranged inside the cartridge. The sample chamber is in communication with the lysis chamber by means of a flow channel. A magnetic bead chamber is further arranged inside the cartridge. The magnetic bead chamber is in communication with the lysis chamber by means of a flow channel. A waste liquid chamber is further arranged inside the cartridge. The waste liquid chamber is in communication with the lysis chamber and the elution chamber by means of flow channels. The cartridge is provided with a first air vent in communication with at least one of the sample chamber and the lysis chamber, a second air vent in communication with the elution chamber, and a reagent inlet in communication with the lysis chamber and the elution chamber.
8.20260022324SYSTEM AND METHOD FOR CREATING TISSUE
US - 22.01.2026
Int.Class C12M 1/36
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
36including condition or time responsive control, e.g. automatically controlled fermentors
 Appl.No 19273313 Applicant DEKA Products Limited Partnership Inventor Christopher C. Langenfeld

A system and method for growing and maintaining biological material including producing a protein associated with the tissue, selecting cells associated with the tissue, expanding the cells, creating at least one tissue bio-ink including the expanded cells, printing the at least one tissue bio-ink in at least one tissue growth medium mixture, growing the tissue from the printed at least one tissue bio-ink, and maintaining viability of the tissue.

9.20260022327DEVICE AND METHOD FOR AUTOMATIC CELLULAR SORTING AND ANALYSIS VIA ROBOTIC MOTOR-DRIVEN FLOW
US - 22.01.2026
Int.Class C12M 1/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
 Appl.No 18993513 Applicant THE REGENTS OF THE UNIVERSITY OF CALIFORNIA Inventor Dino Di Carlo

Automating operations and handling of mesoscale biological objects that range in size from ˜100 μm to ˜1 mm can accelerate the advancement of disease modeling and drug discovery based on organoids and cell-carrier systems. The device leverages flow driven by rotating shafts in a Stokes flow regime to develop a gentle robotic manipulation system for objects based on controllable arrays of micro-motors. The underlying motor-flow mechanics was investigated that enable linear flow control from one pair of motors to an ensemble of reconfigurable motors. This robotic motor-flow driving system can operate in standard cell culture containers (e.g., Petri dish) to perform precise and real-time control of mesoscale cellular constructs in diverse biocompatible carrier fluids such as cell media. Using optional image-based feedback, a fully automated bioparticle sorting system may be created based on the device.

10.WO/2026/018722MEASUREMENT SYSTEM, MEASUREMENT METHOD, AND INFORMATION PROCESSING METHOD
WO - 22.01.2026
Int.Class C12M 1/34
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
34Measuring or testing with condition measuring or sensing means, e.g. colony counters
 Appl.No PCT/JP2025/024238 Applicant SONY SEMICONDUCTOR SOLUTIONS CORPORATION Inventor HORIE Juun
The present technology relates to a measurement system, a measurement method, and an information processing method that make it possible to identify a region of interest with higher accuracy in a shorter period of time. The measurement system comprises a control unit that, for each of a plurality of electrodes included in an MEA disposed in a well in which cells are cultured, identifies a region of interest by performing processing based on measurement information different from measurement information obtained via measurements performed by the electrodes, and either performs new measurements using only electrodes included in the region of interest or deletes measurement information obtained by electrodes other than those included in the region of interest from the measurement information of the plurality of electrodes. The present technology can be applied to a measurement system.
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