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IC:C12M

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Analysis

1 / 28,355
1.3031876CONJUGATION DEVICE AND METHOD FOR PRODUCING CONJUGATES
ES - 11.07.2025
Int.Class C12M 1/40
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
40Apparatus specially designed for the use of free, immobilised, or carrier-bound enzymes, e.g. apparatus containing a fluidised bed of immobilised enzymes
 Appl.No 21925332 Applicant Genequantum Healthcare (Suzhou) Co., Ltd. Inventor QIN, Gang
2.20250223529OPTIMIZED LIGNOCELLULOSIC FEEDSTOCK DIGESTION
US - 10.07.2025
Int.Class C12M 1/107
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
107with means for collecting fermentation gases, e.g. methane
 Appl.No 18984303 Applicant Lee Duane Hansen Inventor Lee Duane Hansen

The disclosed technologies provide a multi-stage system and process for converting lignocellulosic feedstock into high-quality methane-rich biogas. The technologies include an initial anaerobic secretome bioreactor (ASB1) operating under low-moisture, mesophilic conditions, which maximizes enzymatic hydrolysis, acetogenesis, and partial acidogenesis of the feedstock while producing biogas. ASB1 produces a semi-solid effluent rich in partially degraded organic compounds, residual lignin, and microbial biomass. A subsequent thermophilic anaerobic secretome bioreactor (ASB2) accepts this effluent as a substrate and facilitates further enzymatic breakdown and pasteurization through thermophilic microbial activity, producing an effluent optimized for methanogenesis. The final methanogenic digestion stage processes ASB2's effluent, converting it into methane with minimal carbon dioxide content, thus enhancing biogas quality and yield. This multi-stage process efficiently breaks down complex organic materials while minimizing inhibitory byproducts, enabling high-efficiency biogas production suitable for energy applications.

3.20250223548METHOD FOR IN VITRO FERTILIZATION IN A BIOREACTOR
US - 10.07.2025
Int.Class C12N 5/075
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
07Animal cells or tissues
071Vertebrate cells or tissues, e.g. human cells or tissues
075Oocytes; Oogonia
 Appl.No 19001054 Applicant David A. Wolf Inventor David A. Wolf

A highly effective technique for fertilizing an oocyte with a sperm cell to produce a zygote can be carried out in a bioreactor and the zygote can optionally be cultured in the bioreactor into a blastocyst stage embryo for implantation into the uterus of a female recipient. The success rate and probability of fertilization is enhanced by operating the bioreactor reactor under conditions of inter-galactic motion which increases the probability of the sperm coming in close proximity to and fertilizing the oocyte. This method involves the steps of collecting an oocyte from a female donor, collecting sperm from a male donor, fertilizing the oocyte with the sperm in a rotating bioreactor to produce a zygote, culturing the zygote into a blastocyst stage embryo, and implanting the blastocyst stage embryo into a uterus of a recipient female.

4.112023003679SET UMFASSEND EINE MIKROPLATTE, EINEN DECKEL UND EINE VORRICHTUNG ZUM LÖSEN EINER SCHNAPPVERBINDUNG ZWISCHEN MIKROPLATTE UND DECKEL
DE - 10.07.2025
Int.Class B01L 3/00
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
3Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
 Appl.No 112023003679 Applicant Eppendorf SE Inventor Schwarzwald Detlef
5.20250223530SYSTEMS AND METHODS FOR PASSAGING ORGANOIDS
US - 10.07.2025
Int.Class C12M 3/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
3Tissue, human, animal or plant cell, or virus culture apparatus
 Appl.No 18847138 Applicant Molecular Devices (Austria) GmbH Inventor Josef Atzler

A microplate includes a cultivation well, a feeding well, and at least one separation channel there between. The cultivation well, feeding well, and the separation channel each contain a first solution, and the cultivation well contains a subject organoid. A method of using such a microplate includes sealingly engaging a pipette with the feeding well. At least some of the first solution is aspirated into the pipette while maintaining the seal between the pipette and the feeding well. This causes the aspirated portion of the first solution to flow from the cultivation well, through the separation channel, and into the feeding well. A second solution is injected from the pipette while maintaining the seal between the pipette and the feeding well. The injected second solution flows from the feeding well, through the at least one separation channel, and into the cultivation well.

6.20250223537CULTURE DEVICE HAVING TIME-LAPSE SHOOTING FUNCTION AND CULTURE METHOD
US - 10.07.2025
Int.Class C12M 1/34
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
34Measuring or testing with condition measuring or sensing means, e.g. colony counters
 Appl.No 19093428 Applicant ASTEC CO., LTD. Inventor Hiromu INOUE

Provided is a culture device having a time-lapse shooting function of performing time-lapse shooting, wherein a cell is placed to be cultivated in each well of a culture container including at least one or more wells. The culture device includes: a shooting means shooting an image of each well of the culture container in a predetermined time-lapse shooting cycle; a detection means detecting presence/absence of a cell within each well of the culture container; and an image recording means recording an image of a well wherein the presence of the cell is detected by the detection means among images of each well shot by the shooting means.

7.112023003670MIKROFLUIDISCHE VORRICHTUNG UND VERFAHREN ZUR VERWENDUNG DER MIKROFLUIDISCHEN VORRICHTUNG
DE - 10.07.2025
Int.Class C12M 3/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
3Tissue, human, animal or plant cell, or virus culture apparatus
 Appl.No 112023003670 Applicant TOHOKU INSTITUTE OF TECHNOLOGY Inventor Suzuki Ikuro

Eine mikrofluidische Vorrichtung umfasst: eine erste Kammer, die in der Lage ist, Nervenzellen zu kultivieren, und einen Kanal, der sich seitlich von der ersten Kammer erstreckt, wobei der Kanal in der Lage ist, Neuriten zu kultivieren, die aus den Nervenzellen wachsen, wobei der Kanal ein erstes Ende, das mit der ersten Kammer in Verbindung steht, und ein zweites Ende gegenüber dem ersten Ende hat, der Kanal einen Barriereabschnitt an einer vom zweiten Ende entfernten Stelle aufweist, um ein Niveau eines Teils einer Deckenfläche des Kanals abzusenken und den Eintritt der Nervenzellen zu begrenzen. embedded image

8.20250223534INCUBATOR
US - 10.07.2025
Int.Class C12M 3/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
3Tissue, human, animal or plant cell, or virus culture apparatus
 Appl.No 19016843 Applicant Nexpring US Opco Inc. Inventor Erin E. Roberts

A device for culturing specimens may include a housing and a conveyor disposed within the housing, where the conveyor is translatable in vertical directions. The device may further include a plurality of plate holders disposed along a length of the conveyor, such that each plate holder of the plurality of plate holders can be moved to different positions along the length of the conveyor by a translation of the conveyor in the vertical directions. The device may further include an isolation chamber movable between a first position and a second position. The isolation chamber may include an opening and a door. The isolation chamber may be configured such that when the isolation chamber is in the second position, a first plate holder of the plurality of plate holders is isolated from a rest of the housing by the isolation chamber.

9.20250223533METHOD AND APPARATUS FOR CONSTRUCTING MICROFLUIDIC BONE ORGANOID-ON-CHIP
US - 10.07.2025
Int.Class C12M 3/06
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
3Tissue, human, animal or plant cell, or virus culture apparatus
06with filtration, ultrafiltration, inverse osmosis or dialysis means
 Appl.No 18964723 Applicant China-Japan Friendship Hospital (China-Japan Friendship Clinical Medical Research Institute) Inventor Fuqiang GAO

A method for constructing a microfluidic bone organoid-on-chip can continuously observe the impacts of different external factors on a bone tissue structure based on the “ternary regulation theory” of bone angiogenesis-bone resorption-osteogenesis coupling. The method includes: (1) building a visual three-dimensional cell cultivation platform to continuously observe impacts of different external factors on a ternary regulation theory based on angiogenesis of osteoclast precursors, osteoblasts and osteoclasts, such that a user is allowed to directly observe interactions among various kinds of cells; (2) designing microfluidic channels in a chip to allow a reagent involved to present a concentration gradient distribution in the chip; and (3) adding three bioinks including osteoblasts, osteoclasts and vascular endothelial cells respectively, so as to reflect the three cell components individually, in pairs, and as a whole in the chip. An apparatus for constructing a microfluidic bone organoid-on-chip is further provided.

10.202025102595Ein System zur Isolierung, Identifizierung und Analyse von Pilzendophyten aus ausgewählten Heilpflanzen
DE - 10.07.2025
Int.Class C12M 1/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
 Appl.No 202025102595 Applicant Chowdappa Srinivas Inventor

Ein System zur Isolierung, Identifizierung und Diversitäts- und Enzymanalyse endophytischer Pilze aus Heilpflanzen, bestehend aus: eine Pflanzengewebeverarbeitungseinheit, die für die Verarbeitung von frischem und gesundem Gewebe von Heilpflanzen konfiguriert ist; eine Sterilisationsvorrichtung, die dazu konfiguriert ist, die Oberflächen des Pflanzengewebes zu sterilisieren; eine Isolationskammer, die mit Kulturmedien zum Isolieren endophytischer Pilze aus den sterilisierten Pflanzengeweben ausgestattet ist; eine Inkubationseinheit, die so konfiguriert ist, dass sie optimale Wachstumsbedingungen für die endophytischen Pilze aufrechterhält; eine Einheit zur morphologischen Identifizierung, die optische Geräte umfasst, die so konfiguriert sind, dass sie kulturelle Merkmale, Fruchtkörper und Sporen isolierter Pilze untersuchen; eine Diversitätsanalyseeinheit, die dazu konfiguriert ist, Häufigkeitsindizes, Isolationsraten und Kolonisierungsraten der endophytischen Pilze zu berechnen; und ein Enzym-Screening-Gerät mit substratspezifischen Medienplatten, das zum Testen der extrazellulären Enzymaktivität konfiguriert ist. embedded image

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