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IC:C07H

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Analysis

1 / 28,059
1.3050312METHOD FOR PREPARING DIOSMIN AND FLAVONOID FRACTION
ES - 19.12.2025
Int.Class C07H 1/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
1Processes for the preparation of sugar derivatives
 Appl.No 22744691 Applicant Les Laboratoires Servier Inventor SARI, Ozkan
2.P20251298METHOD FOR PREPARING DIOSMIN AND FLAVONOID FRACTION
HR - 19.12.2025
Int.Class C07H 1/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
1Processes for the preparation of sugar derivatives
 Appl.No P20251298T Applicant Les Laboratoires Servier Inventor Ozkan Sari
3.20250382465POLYMERIC DYES WITH LINKER GROUPS COMPRISING DEOXYRIBOSE
US - 18.12.2025
Int.Class C09B 69/10
CCHEMISTRY; METALLURGY
09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
BORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES; MORDANTS; LAKES
69Dyes not provided for by a single group of this subclass
10Polymeric dyes; Reaction products of dyes with monomers or with macromolecular compounds
 Appl.No 19251556 Applicant SONY GROUP CORPORATION Inventor Sharat SINGH

Compounds useful as fluorescent or colored dyes are disclosed. The compounds have the following structure (I):

embedded image

or a stereoisomer, tautomer or salt thereof, wherein R1, R2, R3, R4, R5, L1a, L1b, L2, L3, L4, L5, L6, L7, M1, M2, q, w, m and n are as defined herein. Methods associated with preparation and use of such compounds are also provided.

4.20250382324MONOMERS AND METHODS FOR SYNTHESIS OF MODIFIED OLIGONUCLEOTIDES
US - 18.12.2025
Int.Class C07H 21/02
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
21Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
02with ribosyl as saccharide radical
 Appl.No 18878308 Applicant ALNYLAM PHARMACEUTICALS, INC. Inventor Muthiah MANOHARAN

The present disclosure relates to monomers and methods for synthesizing modified oligonucleotides.

5.WO/2025/256544PREPARATION METHOD FOR 1-AMINOALKYL-MODIFIED RIBOFURANOSE DERIVATIVE
WO - 18.12.2025
Int.Class C07D 405/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
405Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
02containing two hetero rings
04directly linked by a ring-member-to-ring- member bond
 Appl.No PCT/CN2025/100366 Applicant FUJIAN SHENGDI PHARMACEUTICAL CO., LTD. Inventor HUANG, Qinggang
The present disclosure provides a preparation method for a 1-aminoalkyl-modified ribofuranose derivative. Specifically, the present disclosure provides a preparation method for a compound represented by formula (III). By means of the method, the yield is high, post-treatment is simple, and the present disclosure is suitable for industrial large-scale production.
6.20250382321MORPHIC FORMS OF 4-AMINO-7-(3,4-DIHYDROXY-5-(HYDROXYMETHYL)TETRAHYDROFURAN-2-YL)-2-METHYL-7H-PYRROLO[2,3-d]PYRIMIDINE-5-CARBOXAMIDE AND USES THEREOF
US - 18.12.2025
Int.Class C07H 19/14
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
19Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro derivatives thereof
02sharing nitrogen
04Heterocyclic radicals containing only nitrogen as ring hetero atom
14Pyrrolo-pyrimidine radicals
 Appl.No 19027475 Applicant Chimerix, Inc. Inventor Roy W. WARE

The present disclosure relates to crystalline morphic forms of 4-amino-7-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl) tetrahydrofuran-2-yl)-2-methyl-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide. The morphic form can be a stable hemihydrate crystalline form.

7.WO/2025/257400SYNTHESIS OF BRANCHED CHAIN OLIGOSACCHARIDES null
WO - 18.12.2025
Int.Class C12P 19/04
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
19Preparation of compounds containing saccharide radicals
04Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
 Appl.No PCT/EP2025/066596 Applicant DSM IP ASSETS B.V. Inventor ZEUNER, Birgitte
This invention relates to enzymatic reactions to make oligosaccharides with branched chain using trans-lacto-N-biosidase.
8.WO/2025/257280METHOD FOR PURIFICATION OF RNA
WO - 18.12.2025
Int.Class C12N 15/10
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
10Processes for the isolation, preparation or purification of DNA or RNA
 Appl.No PCT/EP2025/066312 Applicant MERCK PATENT GMBH Inventor YUSUKE, Akai
The present invention relates to a method for the chromatographic purification of mRNA. For this anion exchange chromatography is performed with dual pH and salt concentration change as well as a chaotrope in the elution buffer.
9.WO/2025/259830COPOLYMERIC COMPOSITIONS AND METHODS OF USE THEREOF
WO - 18.12.2025
Int.Class A61K 47/58
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
50the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
51the non-active ingredient being a modifying agent
56the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
58obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyacrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
 Appl.No PCT/US2025/033274 Applicant BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA Inventor OUPICKY, David
Compositions and methods for the delivery of a therapeutic agent are provided.
10.20250382325DEPROTECTION PROCESSES AND CATION SCAVENGERS FOR USE IN THE SAME
US - 18.12.2025
Int.Class C07K 1/06
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
1General processes for the preparation of peptides
06using protecting groups or activating agents
 Appl.No 19151208 Applicant EXACTMER LIMITED Inventor Charles Jarrett-Wilkins

A process for deprotecting an organic compound is described, involving the use of an acid to remove an acid-labile protecting group, and a cation scavenger to react with the protecting group once it has been removed. Also described are cation scavengers suitable for use in the processes described herein, as well as a method for preparing a defined monomer sequence polymer. The cation scavenger has the following Formula I: A-B-C−D+ wherein A is a group capable of forming a covalent bond with the acid-labile protecting group once removed from the organic compound; B is absent or is a linking moiety; C− is a negatively charged group; and D+ is a counter ion.

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