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1 / 28,102
1.WO/2026/019365APTAMERS AND RIBOSWITCHES OF CANNABIELSOIN FOR IN VITRO AND IN VIVO SENSING
WO - 22.01.2026
Int.Class C07H 21/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
21Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
 Appl.No PCT/SG2025/050474 Applicant NATIONAL UNIVERSITY OF SINGAPORE Inventor ZHANG, Jingyun
Disclosed is an aptamer capable of binding to Cannabielsoin (CBE), wherein the aptamer is: an RNA aptamer having a nucleotide sequence of: CGCGGGCAGUGNNNUGCANNNNNNNNUGUGNNNUAUUAGC (SEQ ID NO: 1); or a DNA aptamer having a nucleotide sequence of: CGCGGGCAGTGNNNTGCANNNNNNNNTGTGNNNTATTAGC (SEQ ID NO: 2), wherein for SEQ ID NO: 1, N is one nucleotide selected from the group consisting of A, G, U and C, and wherein for SEQ ID NO: 2, N is one nucleotide selected from the group consisting of A, G, C and T. Also disclosed is a riboswitch and a DNA expression cassette comprising the aptamer, a composition thereof, and a microbe containing the riboswitch or DNA expression cassette. Further disclosed is a method of detecting CBE produced in a microbe using the aptamer or riboswitch as disclosed herein.
2.WO/2026/019170CULTURE MEDIUM FOR ENHANCING CORDYCEPIN CONTENT USING HERMETIA ILLUCENS ADULT INSECTS AND METHOD FOR EXTRACTING CORDYCEPIN USING SAME
WO - 22.01.2026
Int.Class C07H 19/16
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
19Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro derivatives thereof
02sharing nitrogen
04Heterocyclic radicals containing only nitrogen as ring hetero atom
16Purine radicals
 Appl.No PCT/KR2025/010170 Applicant CIRCULAR BIO CO., LTD Inventor PARK, Hee Sok
Provided is a culture medium for enhancing the content of cordycepin from Cordyceps militaris, wherein the culture medium comprises Hermetia illucens adult insects. According to the present invention, the culture medium can ensure a significantly higher cordycepin yield than conventional grain-based media or pupa-based media by means of a method for extracting cordycepin from Cordyceps militaris cultured using Hermetia illucens adult insects as a host.
3.WO/2026/019367COMPOUNDS, EXTRACELLULAR VESICLES AND USES THEREOF
WO - 22.01.2026
Int.Class C07D 417/14
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
417Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/196
14containing three or more hetero rings
 Appl.No PCT/SG2025/050479 Applicant NATIONAL UNIVERSITY OF SINGAPORE Inventor WANG, Dandan
The present disclosure concerns a compound for in situ labelling and synchronously promoting the secretion of extracellular vesicles from cells. The compound comprises a sugar or glucosamine linked to a drug. The drug may be a photosensitizer. The present disclosure also concerns the extracellular vesicle thereof, and methods of treating a tumor and/or a proliferative disease.
4.202025003413Reduktiv spaltbare Linker zum Einbau in Oligonukleotide
DE - 22.01.2026
Int.Class C07H 21/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
21Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
 Appl.No 202025003413 Applicant biomers.net GmbH Inventor

Phosphoramidit-Verbindungen gekennzeichnet durch folgende Strukturen: embedded imagem, n, k, l jeweils unabhängig voneinander: 0 bis 20 R1: Trityl, Dimethoxytrityl, Monomethoxytrityl, Acetyl, Trifluoracetyl, Benzoyl R2 bis R17 jeweils unabhängig voneinander: H, Alkyl, substituiertes Alkyl, Alkoxy, Halogen, Nitro

5.WO/2026/017826PROTECTED TETRASACCHARIDES, THEIR PROCESS OF PREPARATION AND THEIR USE IN THE SYNTHESIS OF OLIGOSACCHARIDES REPRESENTING SEGMENTS OF O-ANTIGENS FROM DIVERSE SHIGELLA FLEXNERI SEROTYPES
WO - 22.01.2026
Int.Class C07H 15/18
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
15Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
18Acyclic radicals, substituted by carbocyclic rings
 Appl.No PCT/EP2025/070566 Applicant INSTITUT PASTEUR Inventor MULARD, Laurence
The present invention provides protected tetrasaccharides, their process of preparation and their use as common scaffold precursors in the synthesis of oligosaccharides representing segments of the O-antigens from diverse S. flexneri serotypes, comprising for example SF2a, SF3a, SF2b, SF1b, SFX and/or SFY.
6.WO/2026/019822RETINOIC ACID CONJUGATE COMPOUNDS AND USES THEREOF
WO - 22.01.2026
Int.Class C07H 15/18
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
15Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
18Acyclic radicals, substituted by carbocyclic rings
 Appl.No PCT/US2025/037746 Applicant MASTERY BIOTECH CO., LTD. Inventor LIN, Bo-Lin
Provided are compositions including conjugate compounds of a retinoic acid and a covalently linked trisaccharide. Also provided are methods for prevention or treatment of cancer or viral infections.
7.202600221403'-KETOGLYCOSIDE COMPOUND FOR THE SLOW RELEASE OF A VOLATILE ALCOHOL
US - 22.01.2026
Int.Class C07H 15/207
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
15Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
20Carbocyclic rings
207Cyclohexane rings not substituted by nitrogen atoms, e.g. kasugamycins
 Appl.No 19345863 Applicant GLYCOSCIENCE, S.L. Inventor Peter William SUTTON

The present invention relates to a 3′-ketoglycoside compound defined by formula (I) and its use for controlled release of alcohols, in particular alcohols showing an insect repellent effect. It relates also to a process for preparing the 3′-ketoglycoside compound of formula (I). It further relates to a composition comprising a 3′-ketoglycoside compound of formula (I). It relates also to the use of a 3′-ketoglycoside compound of formula (I) for the controlled release of alcohols. It related also to a method of use of such composition.

8.WO/2026/017514PROCESS FOR DE-HAZING OF POLYGLYCOSIDES
WO - 22.01.2026
Int.Class C11D 1/66
CCHEMISTRY; METALLURGY
11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
1Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
66Non-ionic compounds
 Appl.No PCT/EP2025/069625 Applicant BASF SE Inventor BUSCH, Stefan
Process for treating an aqueous solution of an alkyl polyglycoside, wherein the process comprises the following steps: (a) providing a melt or an aqueous solution of an alkyl polyglycoside with a concentration in the range of from 20 to 80 % by weight, (b) treating the solution at a pH value in the range of from 11 to 13 with peroxide, (c) adding a di-, tri- or polycarboxylic acid to the solution obtained from step (b) and thus adjusting the pH value to a value of from 6.0 to 7.0 and thus de-gassing, (d) re-adjusting the pH value of the de-gassed solution from step (c) to 8.5 to 12.0, thereby obtaining an aqueous solution of an alkyl polyglycoside with a concentration in the range of from 15 to 80% by weight and transparent for the naked human eye.
9.202600211881'-ALKYL MODIFIED RIBOSE DERIVATIVES AND METHODS OF USE
US - 22.01.2026
Int.Class A61K 47/54
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
50the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
51the non-active ingredient being a modifying agent
54the modifying agent being an organic compound
 Appl.No 19282328 Applicant Sanegene Bio USA Inc. Inventor Weimin WANG

The present disclosure provides linker compounds of Formula (I) or (II):

embedded image

pharmaceutically acceptable salts thereof, and related scaffolds and conjugates. The present disclosure also relates to uses of the linker compounds, scaffolds, and conjugates, e.g., in delivering nucleic acid and/or treating or preventing diseases.

10.WO/2026/020020MICRONUTRIENT-STABILIZING MATERIALS
WO - 22.01.2026
Int.Class C07F 15/02
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
FACYCLIC, CARBOCYCLIC, OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
15Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
02Iron compounds
 Appl.No PCT/US2025/038083 Applicant MASSACHUSETTS INSTITUTE OF TECHNOLOGY Inventor LANGER, Robert, S.
Provided herein are metal-organic frameworks, and compositions, food products, beverages, nutritional supplements and kits thereof, as well as associated methods and uses. The metal-organic frameworks provided herein are biocompatible and are useful for delivery of guest molecules for the treatment and/or prevention of various diseases and conditions.
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