This disclosure provides an oral-nasal face mask with a multi-layer seal surface. The multi-layer seal surface includes one or more porous membranes, one or more open cell foams, or combinations thereof. The multi-layer seal surface engages a user's face so that the oral-nasal face mask encloses a space over the user's nasal openings and mouth. The oral-nasal face mask includes a vacuum line connected to a vacuum source for removal of air, vapor, moisture, and other gases from the multi-layer seal surface, where the vacuum line is fluidly coupled to the one or more open cell foams or the one or more porous membranes. The oral-nasal face mask improves sealing to the user's face while preventing leakage of gas from the oral-nasal face mask and ingress of ambient air.

A regionally integrated emergency stroke unit includes an information interaction area, an imaging examination area, and a thrombolytic therapy area. A doctor workstation, a comprehensive information surveillance monitor, and a process support artificial intelligence (AI) assistant are set in the information interaction area. A test device, a first television display, a movable low-field magnetic resonance imager, and an AI-assisted decision-making system are set in the imaging examination area. The process support AI assistant performs, via voice interaction or touchscreen keying interaction, automatic inquiry and auxiliary nervous system scale scoring, and further provides real-time retrieval support for a knowledge base and a clinical guideline. The AI-assisted decision-making system is configured to assist in decision-making based on an automatic inquiry result, a scale score result, the test result, and magnetic resonance imaging results of the head and neck, to generate and display a therapy regimen.