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1 / 65,206
1.WO/2023/204772MINI-SCREWS ANCHORED CASTED PALATAL PLATE FOR UPPER ARCH DISTALIZATION
WO - 26.10.2023
Int.Class A61C 7/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
CDENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
7Orthodontics, i.e. obtaining or maintaining the desired position of teeth, e.g. by straightening, evening, regulating, separating, or by correcting malocclusions
02Tools for manipulating or working with an orthodontic appliance
 Appl.No PCT/SY2022/050001 Applicant RAGHIS, Tuqa Rashad Inventor RAGHIS, Tuqa Rashad
A custom-made appliance designed for total distalization of the upper dental arch. It consists of a Vitallium bar with two posterior holes for mini-screws' insertion localized at the para-median area, and two extended lever arms with two posterior hooks. The palatal plate should be applied with a stainless steel anterior trans-palatal arch, which is inserted in the palatal tubes of the maxillary first molars' bands and provided with two anterior soldered hooks. Distalization of the upper arch can be accomplished by applying an elastic chain or closed coil spring from the anterior hooks of the trans-palatal arch to the posterior hooks of the palatal plate.
2.WO/2024/005852AUTOMATED PROVISIONING FOR MANAGING OF CONVERSATIONS ACROSS SERVICE DELIVERY NETWORKS
WO - 04.01.2024
Int.Class H04M 9/00
HELECTRICITY
04ELECTRIC COMMUNICATION TECHNIQUE
MTELEPHONIC COMMUNICATION
9Arrangements for interconnection not involving centralised switching
 Appl.No PCT/US2022/045291 Applicant M3G TECHNOLOGY, INC. Inventor MARINARO, Douglas E.
A method for establishing at least three-way conversations between customers, service providers, and brand agents within a service delivery network (SDN) is provided. The method commences with receiving a request from a customer for a service by a brand and collecting metadata associated with the customer. The method continues with receiving identification data associated with a service provider. The service provider is selected by the brand based on at least the metadata. The method further includes initiating a two-way communication channel between the customer and one or more brand agents associated with the brand. The method further includes providing a Uniform Resource Locator to the service provider to join the two-way communication channel. The method further includes initiating an at least three-way conversation between the customer, the service provider, and the one or more brand agents via the two-way communication channel.
3.WO/2024/006842BORDETELLA T CELL EPITOPES, MEGAPOOLS AND USES THEREOF
WO - 04.01.2024
Int.Class A61K 39/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
39Medicinal preparations containing antigens or antibodies
02Bacterial antigens
 Appl.No PCT/US2023/069274 Applicant LA JOLLA INSTITUTE FOR IMMUNOLOGY Inventor SETTE, Alessandro
The present invention includes compositions, including epitope megapools, and methods for detecting the presence of: a Bordetella or an immune response relevant to a Bordetella infection including T cells responsive to one or more Bordetella peptides or proteins comprising, consisting of, or consisting essentially of: one or more amino acid sequences, fusion proteins, a pool of 2 or more peptides, or polynucleotides that expression the amino acid sequences selected from those set forth in any one of Tables 1-20 (SEQ ID NOS: 1 to 2598). The invention further provides vaccines, diagnostics, therapies, and kits, comprising such proteins or peptides.
4.WO/2024/006827METHODS AND SYSTEMS FOR LIGHT-CONTROLLED SURFACE PATTERNING USING PHOTOMASKS
WO - 04.01.2024
Int.Class B01J 19/00
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
19Chemical, physical or physico-chemical processes in general; Their relevant apparatus
 Appl.No PCT/US2023/069258 Applicant 10X GENOMICS, INC. Inventor PRISTINSKI, Denis
Provided in some aspects are methods for light-controlled in situ surface patterning of a substrate using a minimal mask scheme. Systems and kits employing the methods are also disclosed. In some embodiments, a method disclosed herein comprises using photomasks and photoresist for photocontrollable hybridization and/or ligation of nucleic acid molecules, wherein photoresist removal allows hybridization and/or ligation of nucleic acid molecules at the exposed area. A large diversity of barcodes can be created in molecules on the substrate via sequential rounds of light exposure, hybridization, and ligation.
5.WO/2024/006797METHODS AND COMPOSITIONS FOR REFINING FEATURE BOUNDARIES IN MOLECULAR ARRAYS
WO - 04.01.2024
Int.Class B01J 19/00
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
19Chemical, physical or physico-chemical processes in general; Their relevant apparatus
 Appl.No PCT/US2023/069221 Applicant 10X GENOMICS, INC. Inventor RAMACHANDRAN IYER, Eswar Prasad
Provided in some aspects are methods for light-controlled in situ surface patterning of a substrate. Compositions such as nucleic acid arrays produced by the methods are also disclosed. Further provided in some aspects are methods for light-controlled in situ refinement of nucleic acid array feature boundaries. In some embodiments, a method disclosed herein comprises using photoresist for photocontrollable removal, blocking, and/or inactivation of nucleic acid molecules at feature boundaries. A large diversity of barcodes can be created in molecules on the substrate via sequential rounds of light exposure, hybridization, ligation, and further interceded and/or followed by one or more rounds of photocontrollable refinement of array feature boundaries, to improve spatial array resolution and sensitivity.
6.WO/2024/006782METHODS AND COMPOSITIONS FOR TREATING PANCREATIC CANCER
WO - 04.01.2024
Int.Class A61K 31/7105
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
7088Compounds having three or more nucleosides or nucleotides
7105Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
 Appl.No PCT/US2023/069201 Applicant SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE Inventor KAUFMAN, Randal J.
Methods and compositions related to treating pancreatic cancer are described.
7.WO/2024/253577VIDEO GENERATION METHOD
WO - 12.12.2024
Int.Class G06N 3/0475
GPHYSICS
06COMPUTING; CALCULATING OR COUNTING
NCOMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
3Computing arrangements based on biological models
02Neural networks
04Architecture, e.g. interconnection topology
0475Generative networks
 Appl.No PCT/SG2024/050285 Applicant ALIBABA INNOVATION PRIVATE LIMITED Inventor WANG, Jiuniu
Provided in the embodiments of the present disclosure is a video generation method. The method comprises: determining text to be processed, and generating initial noise; inputting the initial noise and said text into a video generation model, and in the video generation model, respectively processing the initial noise and said text in a temporal dimension and a spatial dimension by using a spatio-temporal processing unit, so as to obtain at least two video frame representations and a temporal relationship of the at least two video frame representations, wherein the video generation model is obtained by means of performing training according to a text sample, a video frame representation sample corresponding to the text sample, and a noise-added video frame representation sample, and the noise-added video frame representation sample is obtained by means of adding noise to the video frame representation sample according to sample noise; and according to the at least two video frame representations and the temporal relationship of the at least two video frame representations, determining a target video corresponding to said text. Thus, generation of single video frames and generation of a temporal relationship between the single video frames can be realized, thereby ensuring the inter-frame consistency of the video frames.
8.WO/2024/253607AN EXTENDED DEPTH OF FIELD LENS
WO - 12.12.2024
Int.Class A61F 2/16
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
2Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
02Prostheses implantable into the body
14Eye parts, e.g. lenses or corneal implants; Artificial eyes
16Intraocular lenses
 Appl.No PCT/TR2023/050546 Applicant VSY BIYOTEKNOLOJI VE ILAC SANAYI A.S. Inventor HOLMSTRÖM, Sven Thage Sigvard
Presently disclosed is an ophthalmic multifocal lens providing far, intermediate, and near vision as well as an enhanced depth-of-field. According to multiple embodiments, disclosed EDOF lenses minimize undesired photic phenomena, provide seamless far and intermediate vision, with a plateau of vision connected to far vision rather than isolated sharp intensity peaks, and accommodate various pupil sizes, disclosing lenses with additions above 2D, allow shaping of the addition curve, and maintain sharp far vision under different lighting conditions, with phase-shifting structures that have relatively low height.
9.WO/2024/007022MULTI-TIER DIGITAL BEAMFORMING
WO - 04.01.2024
Int.Class H04B 7/06
HELECTRICITY
04ELECTRIC COMMUNICATION TECHNIQUE
BTRANSMISSION
7Radio transmission systems, i.e. using radiation field
02Diversity systems; Multi-antenna systems, i.e. transmission or reception using multiple antennas
04using two or more spaced independent antennas
06at the transmitting station
 Appl.No PCT/US2023/069557 Applicant INNOPHASE, INC. Inventor KAVER, Yaniv
A method and apparatus for multi-tier beamforming are disclosed. The method includes receiving a first-tier beamformed frequency-domain IQ data packet and a plurality of second-tier beamformed frequency-domain IQ data packets at a transceiver integrated circuit (IC) subarray. Each transceiver IC of the transceiver IC subarray (i) forms a multi-tier beamformed frequency-domain IQ data set by combining beamformed frequency-domain IQ data from the first-tier beamformed frequency-domain IQ data packet with beamformed frequency-domain IQ data from selected ones of the second-tier beamformed frequency‑domain IQ data packets, (ii) generates a discrete-time-domain signal from the multi-tier beamformed frequency-domain IQ data set, and (ii) generates a modulated radio frequency (RF) signal from the discrete-time-domain signal. The method further includes transmitting a multi-tier beamformed signal by transmitting respective modulated RF signals from the transceiver ICs of the transceiver IC subarray via a corresponding adjacent antenna element subarray.
10.WO/2024/006947SURFACE DISPLAYED FUSION PROTEINS
WO - 04.01.2024
Int.Class C40B 40/02
CCHEMISTRY; METALLURGY
40COMBINATORIAL TECHNOLOGY
BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
40Libraries per se, e.g. arrays, mixtures
02Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
 Appl.No PCT/US2023/069438 Applicant CLARA FOODS CO. Inventor ZHONG, Weixi
The present disclosure provides engineered eukaryotic cells comprising a surface displayed fusion proteins comprising a catalytic domain of an enzyme and an anchoring domain of a glycosylphosphatidylinositol (GPI)-anchored protein and methods of use.
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