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1 / 85,896
1.WO/2025/015036AAV GENE THERAPY APPROACH FOR TREATING LGMD2B/DYSFERLINOPATHY
WO - 16.01.2025
Int.Class A61K 38/17
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17from animals; from humans
 Appl.No PCT/US2024/037366 Applicant KATE THERAPEUTICS, INC. Inventor TABEBORDBAR, Mohammadsharif
This disclosure relates to compositions and methods for the treatment of dysferlinopathies.
2.WO/2026/024290TURBINE ENCLOSURE VENTILATION AIR DUCTING FOR AIR HANDLING TRANSPORT
WO - 29.01.2026
Int.Class H02K 9/10
HELECTRICITY
02GENERATION, CONVERSION, OR DISTRIBUTION OF ELECTRIC POWER
KDYNAMO-ELECTRIC MACHINES
9Arrangements for cooling or ventilating
10by gaseous cooling medium flowing in closed circuit, a part of which is external to the machine casing
 Appl.No PCT/US2024/039784 Applicant TYPHON TECHNOLOGY SOLUTIONS, LLC Inventor MORRIS, Jeffrey G.
An air handling transport includes a base frame and a combustion air module mounted to the base frame. The combustion air module includes a combustion air plenum for providing filtered combustion air to a turbine mounted on a separate transport. The transport further includes a ventilation air module mounted to the base frame. The ventilation air module provides filtered ventilation air to an enclosure for the turbine mounted on the separate transport. The ventilation air module includes a ventilation air compartment, a ventilation air duct, and a ventilation air plenum. The ventilation air duct is in the base frame and extends below the ventilation air compartment, the combustion air module, and the ventilation air plenum. The ventilation air duct couples the ventilation air compartment to the ventilation air plenum.
3.WO/2026/024305EXCITATION AND MEASUREMENT OF TWIST MODE IN A CORIOLIS FLOWMETER
WO - 29.01.2026
Int.Class G01F 1/84
GPHYSICS
01MEASURING; TESTING
FMEASURING VOLUME, VOLUME FLOW, MASS FLOW, OR LIQUID LEVEL; METERING BY VOLUME
1Measuring the volume flow or mass flow of fluid or fluent solid material wherein the fluid passes through a meter in a continuous flow
76Devices for measuring mass flow of a fluid or a fluent solid material
78Direct mass flowmeters
80operating by measuring pressure, force, momentum, or frequency of a fluid flow to which a rotational movement has been imparted
84Coriolis or gyroscopic mass flowmeters
 Appl.No PCT/US2024/057116 Applicant MICRO MOTION, INC. Inventor DEACY, James S.
A Coriolis flowmeter (5) is provided having a sensor assembly (10) in communication with meter electronics (20). The sensor assembly (10) comprises a flowtube (103, 103'). A driver (104) is in communication with at least one flowtube (103, 103'), and receives a drive signal and oscillates the flowtube (103, 103') in a first bending mode. First and second pickoffs (105, 105') are in communication with the flowtube (103, 103'). The meter electronics (20) receives oscillatory signals generated from the first and second pickoffs (105, 105'). The driver (104) and the first and second pickoffs (105, 105') communicate with meter electronics (20) over a signal path (204). A module (200) temporarily exchanges communication paths between the first pickoff (105) and the driver (104), and the first pickoff (105) receives the drive signal and the driver (104) generates oscillatory signals sent to the meter electronics (20).
4.WO/2025/259581MICROBIAL ENGINEERING FOR THE PRODUCTION OF ALPHA-SUBSTITUTED 3-HYDROXY ACIDS
WO - 18.12.2025
Int.Class C12N 1/20
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
1Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
20Bacteria; Culture media therefor
 Appl.No PCT/US2025/032838 Applicant MASSACHUSETTS INSTITUTE OF TECHNOLOGY Inventor PRATHER, Kristala L. Jones
Disclosed herein are biological pathways and recombinant microorganisms useful, in some aspects, for the production of a-substituted 3-hydroxy acids and precursors thereof, as well as methods of their use.
5.WO/2026/024380CONTROLLING A DUAL-AMPLIFIER POWER AMPLIFIER CIRCUIT IN A POWER MANAGEMENT CIRCUIT
WO - 29.01.2026
Int.Class H03F 1/02
HELECTRICITY
03ELECTRONIC CIRCUITRY
FAMPLIFIERS
1Details of amplifiers with only discharge tubes, only semiconductor devices or only unspecified devices as amplifying elements
02Modifications of amplifiers to raise the efficiency, e.g. gliding Class A stages, use of an auxiliary oscillation
 Appl.No PCT/US2025/033449 Applicant QORVO US, INC. Inventor KHLAT, Nadim
Methods for controlling a dual-amplifier power amplifier circuit in a power management circuit are provided. The dual-amplifier power amplifier circuit includes a first power amplifier that is always active to amplify a radio frequency (RF) signal and a second power amplifier that is only activated to further amplify the RF signal when an instantaneous power level of the RF signal is above a specific power threshold. The dual-amplifier power amplifier circuit is notably different from a Doherty power amplifier circuit in that the power threshold for activating the second power amplifier is significantly lower than a corresponding power threshold used in the Doherty power amplifier circuit. By activating the second power amplifier at a significantly lower power threshold, the first power amplifier and the second power amplifier can each operate in full compression in a respective power region, thus helping to improve overall efficiency of the power management circuit.
6.WO/2026/020195NUCLEIC ACIDS DELIVERED BY HD-MAP
WO - 29.01.2026
Int.Class A61K 39/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
39Medicinal preparations containing antigens or antibodies
 Appl.No PCT/AU2025/050781 Applicant VAXXAS PTY LIMITED Inventor FORSTER, Angus
The present invention relates to stable nucleic acid formulations for administration via a microprojection array in which the microprojections are densely packed and in which the formulations are rapidly sprayed or layered on to the microprojections in relatively small amounts such that the formulations dry rapidly. The present invention relates in particular to nucleic acid cancer vaccines delivered by high density micro-array MAPs (HD-MAP).
7.WO/2026/020210AGENT FOR INHIBITING THE ENZYMES OF BIOFILM-PRODUCING ORAL MICROORGANISMS AND A METHOD FOR ITS PRODUCTION
WO - 29.01.2026
Int.Class A61K 36/736
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
736Prunus, e.g. plum, cherry, peach, apricot or almond
 Appl.No PCT/BG2025/050005 Applicant PRAEVA BIOTECH EDРK Inventor VENEVA-RAYCHINOVA, Elitsa Romanova
The present invention relates to an agent for inhibiting the enzymes of biofilm- producing oral microorganisms and a method for its production, and will find application in the field of dentistry, in particular for the prevention of plaque-related diseases in the oral cavity such as dental caries and periodontal diseases The created agent for inhibiting the enzymes of biofilm-producing oral microorganisms contains the following components in the corresponding weight percentages: vegetable oil from the kernel of a plant of the genus Prunus spp. from 12 to 13%; liquid enzyme preparation of microbial origin from 0.10 to 0.13%; sodium hydroxide from 5 to 6%; hexane from 9 to 10%; hydrochloric acid from 5 to 6.5%; anhydrous sodium sulfate from 3 to 4.4%; methyl orange from 0.004 to 0.008%; alcohol from 0.60 to 0.90%; water from 60 to 69% and tocopherol from 0 to 1%. The vegetable oil is from the kernels of plum - Prunus domestica, apricot - Prunus armeniaca or almond - Prunus dulcis.
8.WO/2025/216773PIEZOELECTRIC MECHANOCHEMICAL DECONTAMINATION SYSTEM AND METHOD FOR THE DESTRUCTION OF PER AND POLYFLUORINATED SUBSTANCES
WO - 16.10.2025
Int.Class B08B 3/12
BPERFORMING OPERATIONS; TRANSPORTING
08CLEANING
BCLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
3Cleaning by methods involving the use or presence of liquid or steam
04Cleaning involving contact with liquid
10with additional treatment of the liquid or of the object being cleaned, e.g. by heat, by electricity or by vibration
12by sonic or ultrasonic vibrations
 Appl.No PCT/US2025/010100 Applicant CLARKSON UNIVERSITY Inventor YANG, Yang
The present invention to is directed to a piezoelectric mechanochemical decontamination system. The system includes a piezoelectric material, impact medium, and dynamic impact device having a receiving chamber that receives the piezoelectric material, impact medium, and a PFAS-contaminated substance having a solid-and/or semi-solid-state PFAS. The dynamic impact device causes the impact medium to collide with the piezoelectric material to thereby cause a piezoelectric reaction that converts one-hundred percent of fluorine included in the PFAS-contaminated substance to fluoride and thereby converts the PFAS-contaminated substance to a decontaminated substance that is environmentally safe for disposal. The piezoelectric material is present at a molar ratio of at least 5:1 compared to the fluorine. The piezoelectric material includes boron nitride. The impact medium includes stainless steel or zirconium. The dynamic impact device is a planetary ball mill device, tumbler mill device, attritor mill device, or vibratory ball mill device.
9.WO/2026/024320SYSTEM AND METHOD FOR REMOTELY MONITORING PATHOLOGICAL FUNCTIONS AND CONDITIONS WITH MULTI-SPECTRAL, CHIP-BASED LIDAR
WO - 29.01.2026
Int.Class Appl.No PCT/US2025/015294 Applicant SVI TECHNOLOGIES, INC. Inventor STEINTHAL, M. Gregory
Various implementations of the invention relate to a silicon-embedded multi- spectral lidar system and method for non-invasive, remote monitoring of pathological conditions of an individual. The system integrates multiple laser sources, photodetectors, and a processing module onto a silicon chip, enabling the capture and analysis of spatial, spectral, scattering and temporal data from a target subject (e.g., individual). By utilizing lidar signals at various wavelengths, various implementations of the invention detect three-dimensional ("3D") surface and subsurface features such as micro-movements, vascular patterns, pigmentation changes, and tissue differences and/or irregularities. Machine learning algorithms process this information from the lidar to identify and classify abnormalities, enabling applications such as heart rate and respiration monitoring, eye movement tracking for neurological and mental health assessment, and detection of pathological skin conditions like cancer. Various implementations of the invention operate in real-time, adapt to environmental conditions, and support dynamic monitoring over time, thereby providing a comprehensive, non-contact solution for diagnostics and telemedicine, for example. Various implementations of the invention may comprise a compact silicon chip form factor suitable for portable and/or hand-held, scalable health monitoring applications across diverse environments.
10.WO/2026/021755LIGHT DETECTION SYSTEM
WO - 29.01.2026
Int.Class G06F 3/042
GPHYSICS
06COMPUTING; CALCULATING OR COUNTING
FELECTRIC DIGITAL DATA PROCESSING
3Input arrangements for transferring data to be processed into a form capable of being handled by the computer; Output arrangements for transferring data from processing unit to output unit, e.g. interface arrangements
01Input arrangements or combined input and output arrangements for interaction between user and computer
03Arrangements for converting the position or the displacement of a member into a coded form
041Digitisers, e.g. for touch screens or touch pads, characterised by the transducing means
042by opto-electronic means
 Appl.No PCT/EP2025/066984 Applicant AMS-OSRAM AG Inventor JAZAYERI FAR, Mahmoud
The invention relates to a light detection system (1), comprising: - a light emitting device (8) configured to emit light towards a target, - a light detecting device (6), configured to detect light, positioned with a geometrical offset from the light emitting device (8), - a substrate (2), having two surfaces, on one of which the light emitting device (8) and the light detecting device (6) are placed, - a first panel (10), which extends over the substrate (2) on the side of the substrate (2) where the light emitting device (8) and the light detecting device (6) are placed, and - a second panel (12), which is placed between the first panel (10) and the substrate (2) and extending above and at least over the light detecting device (6), and wherein the second panel (12) has an aperture (14, which extends only partly over the light detecting device (6), so that a distance between a center of the aperture (14) and the light emitting device (8) is smaller than the distance between a center of the light detecting device (6) and the light emitting device (8). Furthermore, a corresponding a sensor arrangement and method for manufacturing a light detection system is disclosed.
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