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Results 1-10 of 1,499 for Criteria:CHEM:(FBPFZTCFMRRESA-UHFFFAOYSA-N) Office(s):all Language:en Stemming: false
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Analysis
List Length
TitleCtrPubDate
Appl.NoApplicantInventorInt.Class
Use of substituted hexitols including dianhydrogalactitol and analogs to treat neoplastic disease and cancer stem cells including glioblastoma multforme and medulloblastoma
CN18.03.2015
201380015319.5BROWN DENNISBACHA JEFFREY
A61K 31/35
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
335
having oxygen as the only ring hetero atom, e.g. fungichromin
35
having six-membered rings with one oxygen as the only ring hetero atom
The use of dianhydrogalactitol provides a novel therapeutic modality for the treatment of glioblastoma multiforme and medulloblastoma. Dianhydrogalactitol acts as an alkylating agent on DNA that creates N7 methylation. Dianhydrogalactitol is effective in suppressing the growth of cancer stem cells and is active against tumors that are refractory to temozolomide; the drug acts independently of the MGMT repair mechanism.

結晶化工程の廃棄物を使用して収率を向上した高純度無水糖アルコールの製造方法
JP21.12.2015
2015541682サムヤン コーポレイションリュ,フン
C07B 61/00
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
B
GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
61
Other general methods

本発明は、水素化糖を原料として、無水糖アルコールを製造する技術に関し、
より詳細には、水素化糖(例えば、ヘキシトール)に酸を加え、水素化糖を無水糖アルコールに転換させた後、転換液を蒸留し、蒸留液を溶媒中で結晶化して、高純度無水糖アルコールを製造する方法であって、結晶化工程で発生した母液から結晶化用の溶媒を除去し、その後の生成物を蒸留液及び転換液と共に、蒸留工程に投入する。本発明によれば、無水糖アルコールの全収率を向上することができ、蒸留液の流動性を向上して蒸留効率を向上することができ、更に、廃棄物発生量及び処理費用も低減することができ、低コスト、高効率で高純度の無水糖アルコールを製造することができる。
【選択図】図1


Method for preparing high purity anhydrosugar alcohols by thin film distillation
CN25.03.2015
201380024324.2SAMYANG GENEX CORPORATIONKYUNG DO-HYUN
C07C 29/80
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
29
Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
74
Separation; Purification; Stabilisation; Use of additives
76
by physical treatment
80
by distillation
The present invention relates to a method for preparing high purity anhydrosugar alcohols using hydrogenated sugar, and more specifically, to a method for preparing high purity anhydrosugar alcohols (particularly, isosorbide, isomannide, isoidide, and the like) with a purity of 97.5% or higher (more preferably, 98.5% or higher) and a pH of a distillate of 3.7 or higher (more preferably, 4.0 or higher) in a distillation yield of 87% or higher (more preferably, 90% or higher) by adding an acid to hexitol so as to convert the same into anhydrosugar alcohols, and single-stage distilling the converted product by using an internal condenser type thin film evaporator.

薄膜蒸留による高純度アンヒドロ糖アルコールの製造方法
JP11.06.2015
2015511366サムヤン コーポレイションキョン,ドヒョン
B01D 3/12
B PERFORMING OPERATIONS; TRANSPORTING
01
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
D
SEPARATION
3
Distillation or related exchange processes in which liquids are contacted with gaseous media, e.g. stripping
12
Molecular distillation

本発明は、水素化糖を用いて高純度のアンヒドロ糖アルコールを製造する方法に関し、より詳しくは、ヘキシトールに酸を加えて、アンヒドロ糖アルコールに転換させた後、凝縮器内蔵型の薄膜蒸留器を用いて、転換生成物を1段階で蒸留することにより、純度97.5%以上(より好ましくは、98.5%以上)、蒸留液pH3.7以上(より好ましくは、4.0以上)、蒸留収率87%以上(より好ましくは、90%以上)で、高純度のアンヒドロ糖アルコール(特に、イソソルビド、イソマンニド、イソイジドなど)を製造する方法に関する。
【選択図】図1


Production method for anhydro sugar alcohol having markedly reduced ion content and improved colour characteristics
CN18.03.2015
201380024022.5株式会社三养社郑英在
C07C 29/08
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
29
Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
03
by addition of hydroxy groups to unsaturated carbon-to-carbon bonds, e.g. with the aid of H2O2
04
by hydration of carbon-to-carbon double bonds
05
with formation of absorption products in mineral acids and their hydrolysis
08
the acid being phosphoric acid
The present invention relates to a production method for an anhydro sugar alcohol having a markedly reduced ion content and improved colour characteristics, and, more specifically, relates to a method for producing an anhydrous sugar alcohol having a markedly reduced ion content, markedly lowered electrical conductivity and improved colour characteristics, which is obtained by subjecting hydrogenated sugar (sugar alcohol) to a dehydration reaction and thereby converting same to an anhydrous sugar alcohol and then subjecting distilled water, which has been isolated through a distillation step, to a decolourizing process using activated carbon, and subsequently bringing the resulting decolourized substance into contact with an ion exchange resin.

Production method for anhydro sugar alcohol having markedly reduced ion content and improved colour characteristics
US02.04.2015
14399026SAMYANG CORPORATIONYoung Jae Jung
C07D 493/04
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
493
Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
02
in which the condensed system contains two hetero rings
04
Ortho-condensed systems

The present invention relates to a production method for an anhydro sugar alcohol having a markedly reduced ion content and improved color characteristics, and, more specifically, relates to a method for producing an anhydrous sugar alcohol having a markedly reduced ion content, markedly lowered electrical conductivity and improved color characteristics, which is obtained by subjecting hydrogenated sugar (sugar alcohol) to a dehydration reaction and thereby converting same to an anhydrous sugar alcohol and then subjecting distilled water, which has been isolated through a distillation step, to a decolorizing process using activated carbon, and subsequently bringing the resulting decolorized substance into contact with an ion exchange resin.


Method for preparing high-purity anhydrosugar alcohol having improved yield by using waste from crystallization step
CN15.07.2015
201380058400.1株式会社三养社柳熏
C07C 29/80
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
29
Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
74
Separation; Purification; Stabilisation; Use of additives
76
by physical treatment
80
by distillation
The present invention relates to a technique for preparing an anhydrosugar alcohol using hydrogenated sugar as a raw material and, more specifically, to a technique for preparing a high-purity anhydrosugar alcohol by adding an acid to hydrogenated sugar (for example, hexitol) to convert same to an anhydrosugar alcohol, then distilling the converted liquid, and crystallizing the distilled liquid in a solvent, the technique removing a crystallization solvent from a crystallization mother liquor generated during a crystallization step and then introducing the resultant product together with the distilled liquid and the converted liquid into a distillation step, thereby being capable of improving the total distillation yield of the anhydrosugar alcohol, improving distillation efficiency by improving the mobility of a distillate, and further reducing the amount of generated waste and treatment costs and thus highly efficiently preparing the high-purity anhydrosugar alcohol at reduced costs.

METHOD FOR PREPARING HIGH-PURITY ANHYDROSUGAR ALCOHOL HAVING IMPROVED YIELD BY USING WASTE FROM CRYSTALLIZATION STEP
EP16.09.2015
13853737SAMYANG CORPRYU HOON
C07C 29/80
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
29
Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
74
Separation; Purification; Stabilisation; Use of additives
76
by physical treatment
80
by distillation
The present invention relates to a technique for preparing an anhydrosugar alcohol using hydrogenated sugar as a raw material and, more specifically, to a technique for preparing a high-purity anhydrosugar alcohol by adding an acid to hydrogenated sugar (for example, hexitol) to convert same to an anhydrosugar alcohol, then distilling the converted liquid, and crystallizing the distilled liquid in a solvent, the technique removing a crystallization solvent from a crystallization mother liquor generated during a crystallization step and then introducing the resultant product together with the distilled liquid and the converted liquid into a distillation step, thereby being capable of improving the total distillation yield of the anhydrosugar alcohol, improving distillation efficiency by improving the mobility of a distillate, and further reducing the amount of generated waste and treatment costs and thus highly efficiently preparing the high-purity anhydrosugar alcohol at reduced costs.

Method for preparing high-purity anhydrosugar alcohol using sequential combination of thin film distillation and short path distillation
CN08.07.2015
201380058429.X株式会社三养社柳熏
C07C 29/80
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
29
Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
74
Separation; Purification; Stabilisation; Use of additives
76
by physical treatment
80
by distillation
The present invention relates to a technique for preparing an anhydrosugar alcohol using hydrogenated sugar as a raw material and, more specifically, to a technique for preparing a high-purity anhydrosugar alcohol (in particular, isosorbide, isomannide, isoidide, and the like) having a purity of 98% or higher and containing less than 0.1% of sorbitol and a sorbitan isomer, which are impurities, in a high total distillation yield of 94% or higher (more preferably, 95% or higher) by adding an acid to hydrogenated sugar (for example, hexitol) to convert same to an anhydrosugar alcohol, and then distilling the converted liquid over two or more stages by sequentially using a combination of an external condenser type wiped film evaporator and an internal condenser type short path evaporator.

PRODUCTION METHOD FOR ANHYDRO SUGAR ALCOHOL HAVING MARKEDLY REDUCED ION CONTENT AND IMPROVED COLOUR CHARACTERISTICS
EP18.03.2015
13788148SAMYANG CORPJUNG YOUNG JAE
C07C 29/08
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
29
Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
03
by addition of hydroxy groups to unsaturated carbon-to-carbon bonds, e.g. with the aid of H2O2
04
by hydration of carbon-to-carbon double bonds
05
with formation of absorption products in mineral acids and their hydrolysis
08
the acid being phosphoric acid
The present invention relates to a production method for an anhydro sugar alcohol having a markedly reduced ion content and improved colour characteristics, and, more specifically, relates to a method for producing an anhydrous sugar alcohol having a markedly reduced ion content, markedly lowered electrical conductivity and improved colour characteristics, which is obtained by subjecting hydrogenated sugar (sugar alcohol) to a dehydration reaction and thereby converting same to an anhydrous sugar alcohol and then subjecting distilled water, which has been isolated through a distillation step, to a decolourizing process using activated carbon, and subsequently bringing the resulting decolourized substance into contact with an ion exchange resin.

Results 1-10 of 1,499 for Criteria:CHEM:(FBPFZTCFMRRESA-UHFFFAOYSA-N) Office(s):all Language:en Stemming: false
Filters
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