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Results 1-10 of 1,469 for Criteria:CHEM:(FBPFZTCFMRRESA-UHFFFAOYSA-N) Office(s):all Language:en Stemming: false
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TitleCtrPubDate
Appl.NoApplicantInventorInt.Class
METHOD OF CATALYTIC CONVERSION OF CELLULOSE IN HEXITOLS
RU10.11.2013
2012143179/04Филатова Анастасия Евгеньевна (RU)
C07C 31/26
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
31
Saturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
18
Polyhydroxylic acyclic alcohols
26
Hexahydroxylic alcohols
FIELD: chemistry. SUBSTANCE: invention relates to field of processing renewable raw material (in particular, cellulose) into raw material for chemical synthesis and biofuels. Method of catalytic conversion of cellulose in hexitols includes carrying out process of hydrolytic hydration of cellulose for 3-7 minutes at temperature 240-250°C under partial pressure of hydrogen 55-65 atm and with mixing of reaction medium in presence of ruthenium catalyst, according to invention as substrate for ruthenium catalyst applied is hypercrosslinked polystyrene of MN 270 grade, and content of ruthenium in catalyst constitutes from 1.0 to 1.5 wt % of catalyst weight. Mixing of reaction mixture is realised by propeller mixer, numbers of turns of which constitutes 580-620 rev/min. EFFECT: increased method efficiency. 2 cl, 16 ex

取代的己糖醇例如卫康醇的合成方法
CN28.08.2013
201180050147.6德玛医药丹尼斯·M·布朗
C07D 413/00
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
413
Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms

本发明提供一种合成及纯化双脱水己糖醇(例如卫康醇)的有效方法。一般来说,当应用于卫康醇时,所述方法包含:(1)在约80°C的温度下,将卫矛醇与氢溴酸浓缩液起反应,以生成二溴卫矛醇;(2)将二溴卫矛醇与碳酸钾置入于叔丁醇中起反应,以生成卫康醇;以及(3)使用乙醚的浆料来纯化所述卫康醇,以生成纯化的卫康醇。


PRODUCTION METHOD OF ANHYDROUS SUGAR ALCOHOL HAVING REMARKABLY REDUCED ION CONTENTS AND IMPROVED COLOR CHARACTERISTIC
KR20.11.2013
1020120050188SAMYANG GENEX CORPORATIONJUNG, YOUNG JAE
C07C 29/08
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
29
Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
03
by addition of hydroxy groups to unsaturated carbon-to-carbon bonds, e.g. with the aid of H2O2
04
by hydration of carbon-to-carbon double bonds
05
with formation of absorption products in mineral acids and their hydrolysis
08
the acid being phosphoric acid
The present invention relates to a production method of anhydrous sugar alcohol having remarkably reduced ion contents and improved color characteristic, more specifically to a production method of the anhydrous sugar alcohol having remarkably reduced ion contents and conductivity, and improved color characteristic by dehydrating hydrogenated sugar ​(sugar alcohol) to obtain the anhydrous sugar alcohol, distilling the anhydrous sugar alcohol before decolorizing the distilled product with activated charcoal, and contacting the decolorized product with an ion exchange resin. COPYRIGHT KIPO 2014 >

MANUFACTURING METHOD FOR HIGH PURITY ANHYDROSUGAR ALCOHOLS BY THIN FILM EVAPORATION
KR20.11.2013
1020120050316SAMYANG GENEX CORPORATIONKYUNG, DO HYUN
C07C 29/80
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
29
Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
74
Separation; Purification; Stabilisation; Use of additives
76
by physical treatment
80
by distillation
The invention relates to a manufacturing method for high purity anhydrosugar alcohols using hydrogenated sugar as raw materials and, more specifically, to a method for manufacturing high purity anhydrosugar alcohols (especially, isosorbide, isomannide, isoidide etc) with a purity of more than 97.5% (preferably, more than 98.5%) and a pH of a distillate of more than 3.7 (preferably, more than 4.0) in a distillation yield of more than 87% (preferably, more than 90%) by adding an acid to hexitol so as to convert the same into anhydrosugar alcohols, and single-stage distilling the converted products by using an internal condenser type thin film evaporator. COPYRIGHT KIPO 2014

BIVALENT ANTISENSE OLIGONUCLEOTIDES
US28.03.2013
13636459Moeller ThorleifMoeller Thorleif
C12N 15/113
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
11
DNA or RNA fragments; Modified forms thereof
113
Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides

The present invention provides bivalent molecules comprising a first oligonucleotide linked to a second oligonucleotide. The first and the second oligonucleotide are preferably linked via a linking moiety. Preferably, both the first and/or the second oligonucleotide comprise an antisense sequence complementary to a cellular RNA such as mRNA or microRNA.


ジアンヒドロガラクチトール等の置換ヘキシトールの合成方法
JP02.09.2013
2013524951デル マー ファーマスーティカルズデニス エム ブラウン
C07D 301/32
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
301
Preparation of oxiranes
32
Separation; Purification

【課題】ジアンヒドロガラクチトール等のジアンヒドロヘキシトールを合成及び精製する効率的方法を提供する。
【解決手段】一般的に、ジアンヒドロガラクチトールに適用される、該方法は、(1)ジブロモガラクチトールを生成するために、約80℃の温度で、ズルシトールと、臭化水素酸の濃縮液と、を反応させる工程と、(2)ジアンヒドロガラクチトールを生成するために、t−ブタノール中でジブロモガラクチトールと、炭酸カリウムと、を反応させる工程と、(3)精製されたジアンヒドロガラクチトールを生成するために、エチルエーテルの懸濁液を用いて、ジアンヒドロガラクチトールを精製する工程と、を含む。


ジアンヒドロガラクチトール及びジアセチルジアンヒドロガラクチトール等の置換ヘキシトールを含む準最適に投与された化合物の治療的有効性を改良するための組成物及び方法
JP03.10.2013
2013524950デル マー ファーマスーティカルズデニス エム ブラウン
A61K 31/336
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
335
having oxygen as the only ring hetero atom, e.g. fungichromin
336
having three-membered rings, e.g. oxirane, fumagillin

【課題】準最適に投与された化合物及び治療組成物の治療的有効性を改善するための組成物及び方法を提供する。
【解決手段】本発明は、単独療法としての有効性を改善することによって、又は、副作用を低減させることによって、準最適な治療効果によって従前に制限された治療薬の治療的有効性を改善するための方法及び組成物に関する。そのような方法及び組成物は、ジアンヒドロガラクチトール及びジアセチルジアンヒドロガラクチトール等の置換ヘキシトールに、特に適用可能である。


TETRATHIOMOLYBDATE FOR USE IN THE TREATMENT OF ISCHEMIA-REPERFUSION INJURY OF THE HEAD OR BRAIN
EP06.02.2013
11716626MAGNUS TTM ICSINGER MERVYN
A61K 33/24
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
33
Medicinal preparations containing inorganic active ingredients
24
Heavy metals; Compounds thereof
Tetrathiomolybdate is for use in therapy of a condition requiring reduced core temperature, e.g. ischemia-reperfusion injury.

The therapeutic use of tetrathiomolybdate
EP10.04.2013
11183830MAGNUS INTELLECTUAL PROPERTY LTD
A61K 33/24
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
33
Medicinal preparations containing inorganic active ingredients
24
Heavy metals; Compounds thereof
Tetrathiomolybdate is for use in therapy of myocardial infarction or stroke.

Tetrathiomolybdate for use in the treatment of ischemia-reperfusion injury of the heart
EP13.02.2013
12189630MAGNUS TTM ICSINGER MERVYN
A61K 33/24
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
33
Medicinal preparations containing inorganic active ingredients
24
Heavy metals; Compounds thereof
Tetrathiomolybdate (TTM) for use in therapy of ischemia-reperfusion injury, wherein the injury is of the heart.

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