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Analysis

1.20220180975METHODS AND SYSTEMS FOR DETERMINING GENE EXPRESSION PROFILES AND CELL IDENTITIES FROM MULTI-OMIC IMAGING DATA
US 09.06.2022
Int.Class G16B 40/30
GPHYSICS
16INFORMATION AND COMMUNICATION TECHNOLOGY SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
40ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
30Unsupervised data analysis
Appl.No 17553691 Applicant The Broad Institute, Inc. Inventor Aviv Regev

The present disclosure relates to systems and method of determining transcriptomic profile from omics imaging data. The systems and methods train machine learning methods with intrinsic and extrinsic features of a cell and/or tissue to define transcriptomic profiles of the cell and/or tissue. Applicants utilize a convolutional autoencoder to define cell subtypes from images of the cells.

2.20210298688Methods and systems for identifying presence of abnormal heart sounds of a subject
US 30.09.2021
Int.Class A61B 5/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes ; Identification of persons
Appl.No 17060009 Applicant Tata Consultancy Services Limited Inventor Rohan Banerjee

The disclosure generally relates to methods and systems for identifying presence of abnormal heart sounds from heart sound signals of a subject being monitored. Conventional Artificial intelligence (AI) based abnormal heart sounds detection models with supervised learning requires a substantial amount of accurate training datasets covering all heart disease types for the training, which is quiet challenging. The present methods and systems solve the problem solves the problem of identifying presence of the abnormal heart sounds using an efficient semi-supervised learning model. The semi-supervised learning model is generated based on probability distribution of spectrographic properties obtained from heart sound signals of healthy subjects. A Kullback-Leibler (KL) divergence between a predefined Gaussian distribution and an encoded probability distribution of the semi-supervised learning model is determined as an anomaly score for identifying the abnormal heart sounds.

3.WO/2023/154851INTEGRATED FRAMEWORK FOR HUMAN EMBRYO PLOIDY PREDICTION USING ARTIFICIAL INTELLIGENCE
WO 17.08.2023
Int.Class G06T 7/00
GPHYSICS
06COMPUTING; CALCULATING OR COUNTING
TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
7Image analysis
Appl.No PCT/US2023/062368 Applicant CORNELL UNIVERSITY Inventor HAJIRASOULIHA, Iman
The present disclosure encompasses systems and methods for predicting embryo ploidy. Specific embodiments encompass methods of non-invasively predicting ploidy status of an embryo, by receiving a dataset with a static image of the embryo, analyzing the static image by one or more machine and/or deep learning model via one or more classification task applied to the dataset; and generating an output prediction of the ploidy status of the embryo. Particular methods relate to methods wherein the dataset additionally includes one or more clinical and/or morphological features for the embryo. Embodiments also relate to predicting embryo viability and/or improving embryo selection, such as during in vitro fertilization. and uses thereof.
4.2018101531Stock forecast model based on text news by random forest
AU 01.11.2018
Int.Class G06N 3/08
GPHYSICS
06COMPUTING; CALCULATING OR COUNTING
NCOMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
3Computing arrangements based on biological models
02Neural networks
08Learning methods
Appl.No 2018101531 Applicant CHANG, ZHIHAN MR Inventor CHANG, ZHIHAN
The main purpose of this project is to use random forest (RF) algorithm to analyze the correlation between the stock news on the historical days and the ups and downs of the stocks the next day. We then find out the information hidden behind these data by sorting and screening stocks, that is, the key words or key events related to the rise and fall of the stocks to predict the rise and fall of the stocks in the near future. By using this method, after entering the news data of the stock market on that day, we can predict the rise and fall of one stock the next day. This relatively accurate method can help shareholders get rid of the risk of stock investment and even can guarantee stable investment returns. This model uses random forest algorithm to carry out excavating and classifying the information of text news. Random forest is a combinatorial classifier, which can be used for the classification and screening of the stocks. The essence of it is a set of tree classifiers. Among them, the base classifier H (x, beta k) is a classification decision tree constructed by CART algorithm without pruning. x is the input vector and beta k is an independent and identically distributed random vector which determine the growth process of the single tree (base classifier). The output is determined by a simple majority voting method. Fig.1 General Flow-Chart
5.20220383629Label-free cell classification and screening system based on hybrid transfer learning
US 01.12.2022
Int.Class G06V 10/82
GPHYSICS
06COMPUTING; CALCULATING OR COUNTING
VIMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
10Arrangements for image or video recognition or understanding
70using pattern recognition or machine learning
82using neural networks
Appl.No 17804073 Applicant SHANDONG UNIVERSITY Inventor Xuantao Su

A label-free cell classification and screening system based on hybrid transfer learning, including a data preprocessing module for acquiring 2D light scattering video data and for digital cell filtering, is made public here; the data preprocessing module includes the label-free high-content video flow cytometry, which has the optical excitation module, the sheath flow control module, and the data acquisition and processing module; the image archiving module is used to sort and set labels for cells; in the feature extraction module, the first convolutional neural network is used to obtain image data feature vectors; in the cell classification and screening module, a support vector machine model is used to obtain the cell screening results.

6.5835893Class-based word clustering for speech recognition using a three-level balanced hierarchical similarity
US 10.11.1998
Int.Class G10L 3/00
GPHYSICS
10MUSICAL INSTRUMENTS; ACOUSTICS
LSPEECH ANALYSIS TECHNIQUES OR SPEECH SYNTHESIS; SPEECH RECOGNITION; SPEECH OR VOICE PROCESSING TECHNIQUES; SPEECH OR AUDIO CODING OR DECODING
3Details of devices which are not related to a specific method of analysis or synthesis
Appl.No 08634705 Applicant ATR Interpreting Telecommunications Research Labs Inventor Ushioda Akira

In a word clustering apparatus for clustering words, a plurality of words is clustered to obtain a total tree diagram of a word dictionary representing a word clustering result, where the total tree diagram includes tree diagrams of an upper layer, a middle layer and a lower layer. In a speech recognition apparatus, a microphone converts an input utterance speech composed of a plurality of words into a speech signal, and a feature extractor extracts predetermined acoustic feature parameters from the converted speech signal. Then, a speech recognition controller executes a speech recognition process on the extracted acoustic feature parameters with reference to a predetermined Hidden Markov Model and the obtained total tree diagram of the word dictionary, and outputs a result of the speech recognition.

7.WO/2023/091970LIVE-CELL LABEL-FREE PREDICTION OF SINGLE-CELL OMICS PROFILES BY MICROSCOPY
WO 25.05.2023
Int.Class G16B 25/10
GPHYSICS
16INFORMATION AND COMMUNICATION TECHNOLOGY SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
25ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
10Gene or protein expression profiling; Expression-ratio estimation or normalisation
Appl.No PCT/US2022/079989 Applicant THE GENERAL HOSPITAL CORPORATION Inventor COMITER, Charles
Computer-implemented methods, computer program products, and systems determine an omics profiles of a cell using microscopy imaging data. In one aspect, a computer-implemented method determines an omics profiles of a cell using microscopy imaging data by a) receiving microscopy imaging data of a cell or a population of cells; b) determining a targeted expression profile of a set of target genes from the microscopy imaging data using a first machine learning model, the target genes identifying a cell type or cell state of interest; and c) determining a singlecell omics profile for the population of cells using a second machine learning algorithm model. The targeted expression profile and a reference single-cell RNA-seq data set are used as inputs for the second machine learning model.
8.WO/2025/002066AN AUTOMATED METHOD FOR EVALUATING THEZONA PELLUCIDABINDINGCAPABILITY OF SPERMATOZOAIN CLINICAL ASSISTED REPRODUCTION
WO 02.01.2025
Int.Class G16B 40/00
GPHYSICS
16INFORMATION AND COMMUNICATION TECHNOLOGY SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
40ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
Appl.No PCT/CN2024/101066 Applicant THE UNIVERSITY OF HONG KONG Inventor CHIU, Philip Chi Ngong
Disclosed is an automated method for evaluating the ZP-binding capability of spermatozoa according to their morphological features in assisted reproduction using deep learning. Also provided is a method of predicting fertilization success in clinical assisted reproduction based on the ZP-binding capability of spermatozoa.
9.20140201126Method and system for feature detection
US 17.07.2014
Int.Class G06N 7/00
GPHYSICS
06COMPUTING; CALCULATING OR COUNTING
NCOMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
7Computing arrangements based on specific mathematical models
Appl.No 14218923 Applicant Lotfi A. Zadeh Inventor Lotfi A. Zadeh

Specification covers new algorithms, methods, and systems for artificial intelligence, soft computing, and deep learning/recognition, e.g., image recognition (e.g., for action, gesture, emotion, expression, biometrics, fingerprint, facial, OCR (text), background, relationship, position, pattern, and object), Big Data analytics, machine learning, training schemes, crowd-sourcing (experts), feature space, clustering, classification, SVM, similarity measures, modified Boltzmann Machines, optimization, search engine, ranking, question-answering system, soft (fuzzy or unsharp) boundaries/impreciseness/ambiguities/fuzziness in language, Natural Language Processing (NLP), Computing-with-Words (CWW), parsing, machine translation, sound and speech recognition, video search and analysis (e.g. tracking), image annotation, geometrical abstraction, image correction, semantic web, context analysis, data reliability, Z-number, Z-Web, Z-factor, rules engine, control system, autonomous vehicle, self-diagnosis and self-repair robots, system diagnosis, medical diagnosis, biomedicine, data mining, event prediction, financial forecasting, economics, risk assessment, e-mail management, database management, indexing and join operation, memory management, data compression, event-centric social network, Image Ad Network.

10.20210004437Generating message effectiveness predictions and insights
US 07.01.2021
Int.Class G06F 40/205
GPHYSICS
06COMPUTING; CALCULATING OR COUNTING
FELECTRIC DIGITAL DATA PROCESSING
40Handling natural language data
20Natural language analysis
205Parsing
Appl.No 16458569 Applicant ADOBE INC. Inventor Pin Zhang

Messages are processed to generate effectiveness predictions and/or other insights associated with the messages. Candidate messages are processed through a natural language processing (NLP) component to parse the candidate message into message elements for further processing. The message elements are converted to a vector or set of vectors, which are provided as input to a machine learning model to make predictions of message effectiveness. A contribution score can be made for each message element of the candidate message, which may be indicative of the importance or relevance for the individual message element to the overall predicted message effectiveness. Other message elements not originally within the message can be provided as candidates to replace message elements already located within the message. In this way, a message that is likely to be effective, such being likely to have a high conversion rate, can be published or otherwise distributed.