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Analysis

1 / 2,585
1.20220180975METHODS AND SYSTEMS FOR DETERMINING GENE EXPRESSION PROFILES AND CELL IDENTITIES FROM MULTI-OMIC IMAGING DATA
US - 09.06.2022
Int.Class G16B 40/30
GPHYSICS
16INFORMATION AND COMMUNICATION TECHNOLOGY SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
40ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
30Unsupervised data analysis
 Appl.No 17553691 Applicant The Broad Institute, Inc. Inventor Aviv Regev

The present disclosure relates to systems and method of determining transcriptomic profile from omics imaging data. The systems and methods train machine learning methods with intrinsic and extrinsic features of a cell and/or tissue to define transcriptomic profiles of the cell and/or tissue. Applicants utilize a convolutional autoencoder to define cell subtypes from images of the cells.

2.WO/2023/059663SYSTEMS AND METHODS FOR ASSESSMENT OF BODY FAT COMPOSITION AND TYPE VIA IMAGE PROCESSING
WO - 13.04.2023
Int.Class A61B 5/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes ; Identification of persons
 Appl.No PCT/US2022/045706 Applicant THE BROAD INSTITUTE, INC. Inventor KHERA, Amit
The subject matter disclosed herein relates to utilizing the silhouette of an individual to measure body fat volume and distribution. Particular examples relates to providing a system, a computer-implemented method, and a computer program product to utilize a binary outline, or silhouette, to predict the individual's fat depot volumes with machine learning models.
3.12274503Myopia ocular predictive technology and integrated characterization system
US - 15.04.2025
Int.Class A61B 3/14
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
3Apparatus for testing the eyes; Instruments for examining the eyes
10Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions
14Arrangements specially adapted for eye photography
 Appl.No 18778027 Applicant COGNITIVECARE INC. Inventor Venkata Narasimham Peri

According to an embodiment, disclosed is a system comprising a processor wherein the processor is configured to receive an input data comprising an image of an ocular region of a user, clinical data of the user, and external factors; extract, using an image processing module comprising adaptive filtering techniques, ocular characteristics, combine, using a multimodal fusion module, the input data to determine a holistic health embedding; detect, based on a machine learning model and the holistic health embedding, a first output comprising likelihood of myopia, and severity of myopia; predict, based on the machine learning model and the holistic health embedding, a second output comprising an onset of myopia and a progression of myopia in the user; and wherein the machine learning model is a pre-trained model; and wherein the system is configured for myopia prognosis powered by multimodal data.

4.2017300259Distributed machine learning systems, apparatus, and methods
AU - 25.01.2018
Int.Class G06N 99/00
GPHYSICS
06COMPUTING; CALCULATING OR COUNTING
NCOMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
99Subject matter not provided for in other groups of this subclass
 Appl.No 2017300259 Applicant Nant Holdings IP, LLC Inventor Benz, Stephen Charles
A distributed, online machine learning system is presented. Contemplated systems include many private data servers, each having local private data. Researchers can request that relevant private data servers train implementations of machine learning algorithms on their local private data without requiring de-identification of the private data or without exposing the private data to unauthorized computing systems. The private data servers also generate synthetic or proxy data according to the data distributions of the actual data. The servers then use the proxy data to train proxy models. When the proxy models are sufficiently similar to the trained actual models, the proxy data, proxy model parameters, or other learned knowledge can be transmitted to one or more non-private computing devices. The learned knowledge from many private data servers can then be aggregated into one or more trained global models without exposing private data.
5.WO/2018/017467DISTRIBUTED MACHINE LEARNING SYSTEMS, APPARATUS, AND METHODS
WO - 25.01.2018
Int.Class G06N 99/00
GPHYSICS
06COMPUTING; CALCULATING OR COUNTING
NCOMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
99Subject matter not provided for in other groups of this subclass
 Appl.No PCT/US2017/042356 Applicant NANTOMICS, LLC Inventor SZETO, Christopher
A distributed, online machine learning system is presented. Contemplated systems include many private data servers, each having local private data. Researchers can request that relevant private data servers train implementations of machine learning algorithms on their local private data without requiring de-identification of the private data or without exposing the private data to unauthorized computing systems. The private data servers also generate synthetic or proxy data according to the data distributions of the actual data. The servers then use the proxy data to train proxy models. When the proxy models are sufficiently similar to the trained actual models, the proxy data, proxy model parameters, or other learned knowledge can be transmitted to one or more non-private computing devices. The learned knowledge from many private data servers can then be aggregated into one or more trained global models without exposing private data.
6.20180139047Cryptographic key control based on debasing condition likelihood estimation
US - 17.05.2018
Int.Class H04L 9/14
HELECTRICITY
04ELECTRIC COMMUNICATION TECHNIQUE
LTRANSMISSION OF DIGITAL INFORMATION, e.g. TELEGRAPHIC COMMUNICATION
9Arrangements for secret or secure communications; Network security protocols
14using a plurality of keys or algorithms
 Appl.No 15236043 Applicant Venafi, Inc. Inventor Matthew Woods

In representative embodiments, systems and methods to calculate the likelihood that presented cryptographic key material is untrustworthy are disclosed. A predictive model based on a debasing condition and a dataset is created by evaluating the dataset relative to the debasing condition. For example, if certificate revocation is selected as the debasing condition, the dataset is analyzed to produce a predictive model that determines the likelihood that a presented certificate is untrustworthy based on similarity to already revoked certificates. The predictive model can include a supervised learning model like a logistic regression model or a deep neural network model. The system can be used in conjunction with existing security infrastructures or can be used as a separate infrastructure. Based on the likelihood score calculated by the model, a relying system can reject the cryptographic key material, accept the cryptographic key material or take other further action.

7.20200195435Cryptographic key control based on debasing condition likelihood estimation
US - 18.06.2020
Int.Class H04L 9/14
HELECTRICITY
04ELECTRIC COMMUNICATION TECHNIQUE
LTRANSMISSION OF DIGITAL INFORMATION, e.g. TELEGRAPHIC COMMUNICATION
9Arrangements for secret or secure communications; Network security protocols
14using a plurality of keys or algorithms
 Appl.No 16692319 Applicant Venafi, Inc. Inventor Matthew Woods

In representative embodiments, systems and methods to calculate the likelihood that presented cryptographic key material is untrustworthy are disclosed. A predictive model based on a debasing condition and a dataset is created by evaluating the dataset relative to the debasing condition. For example, if certificate revocation is selected as the debasing condition, the dataset is analyzed to produce a predictive model that determines the likelihood that a presented certificate is untrustworthy based on similarity to already revoked certificates. The predictive model can include a supervised learning model like a logistic regression model or a deep neural network model. The system can be used in conjunction with existing security infrastructures or can be used as a separate infrastructure. Based on the likelihood score calculated by the model, a relying system can reject the cryptographic key material, accept the cryptographic key material or take other further action.

8.10430946Medical image segmentation and severity grading using neural network architectures with semi-supervised learning techniques
US - 01.10.2019
Int.Class G06T 7/00
GPHYSICS
06COMPUTING; CALCULATING OR COUNTING
TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
7Image analysis
 Appl.No 16353800 Applicant Inception Institute of Artifical Intelligence, Ltd. Inventor Yi Zhou

This disclosure relates to improved techniques for performing computer vision functions on medical images, including object segmentation functions for identifying medical objects in the medical images and grading functions for determining severity labels for medical conditions exhibited in the medical images. The techniques described herein utilize a neural network architecture to perform these and other functions. The neural network architecture can be trained, at least in part, using semi-supervised learning techniques that enable the neural network architecture to accurately perform the object segmentation and grading functions despite limited availability of pixel-level annotation information.

9.WO/2021/211787SYSTEMS AND METHODS FOR QUANTIFICATION OF LIVER FIBROSIS WITH MRI AND DEEP LEARNING
WO - 21.10.2021
Int.Class G16H 50/20
GPHYSICS
16INFORMATION AND COMMUNICATION TECHNOLOGY SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
50ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
20for computer-aided diagnosis, e.g. based on medical expert systems
 Appl.No PCT/US2021/027398 Applicant CHILDREN'S HOSPITAL MEDICAL CENTER Inventor DILLMAN, Jonathan
Embodiments provide a deep learning framework to accurately segment liver and spleen using a convolutional neural network with both short and long residual connections to extract their radiomic and deep features from multiparametric MRI. Embodiments will provide an "ensemble" deep learning model to quantify biopsy derived liver fibrosis stage and percentage using the integration of multiparametric MRI radiomic and deep features, MRE data, as well as routinely available clinical data. Embodiments will provide a deep learning model to quantify MRE-derived liver stiffness using multiparametric MRI, radiomic and deep features and routinely-available clinical data.
10.20200160997Method for detection and diagnosis of lung and pancreatic cancers from imaging scans
US - 21.05.2020
Int.Class A61B 5/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes ; Identification of persons
 Appl.No 16673397 Applicant University of Central Florida Research Foundation, Inc. Inventor Ulas Bagci

A method of detecting and diagnosing cancers characterized by the presence of at least one nodule/neoplasm from an imaging scan is presented. To detect nodules in an imaging scan, a 3D CNN using a single feed forward pass of a single network is used. After detection, risk stratification is performed using a supervised or an unsupervised deep learning method to assist in characterizing the detected nodule/neoplasm as benign or malignant. The supervised learning method relies on a 3D CNN used with transfer learning and a graph regularized sparse MTL to determine malignancy. The unsupervised learning method uses clustering to generate labels after which label proportions are used with a novel algorithm to classify malignancy. The method assists radiologists in improving detection rates of lung nodules to facilitate early detection and minimizing errors in diagnosis.

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