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Analysis

1.20220180975METHODS AND SYSTEMS FOR DETERMINING GENE EXPRESSION PROFILES AND CELL IDENTITIES FROM MULTI-OMIC IMAGING DATA
US 09.06.2022
Int.Class G16B 40/30
GPHYSICS
16INFORMATION AND COMMUNICATION TECHNOLOGY SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
40ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
30Unsupervised data analysis
Appl.No 17553691 Applicant The Broad Institute, Inc. Inventor Aviv Regev

The present disclosure relates to systems and method of determining transcriptomic profile from omics imaging data. The systems and methods train machine learning methods with intrinsic and extrinsic features of a cell and/or tissue to define transcriptomic profiles of the cell and/or tissue. Applicants utilize a convolutional autoencoder to define cell subtypes from images of the cells.

2.12274503Myopia ocular predictive technology and integrated characterization system
US 15.04.2025
Int.Class A61B 3/14
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
3Apparatus for testing the eyes; Instruments for examining the eyes
10Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions
14Arrangements specially adapted for eye photography
Appl.No 18778027 Applicant COGNITIVECARE INC. Inventor Venkata Narasimham Peri

According to an embodiment, disclosed is a system comprising a processor wherein the processor is configured to receive an input data comprising an image of an ocular region of a user, clinical data of the user, and external factors; extract, using an image processing module comprising adaptive filtering techniques, ocular characteristics, combine, using a multimodal fusion module, the input data to determine a holistic health embedding; detect, based on a machine learning model and the holistic health embedding, a first output comprising likelihood of myopia, and severity of myopia; predict, based on the machine learning model and the holistic health embedding, a second output comprising an onset of myopia and a progression of myopia in the user; and wherein the machine learning model is a pre-trained model; and wherein the system is configured for myopia prognosis powered by multimodal data.

3.20220139498APPARATUSES, SYSTEMS, AND METHODS FOR EXTRACTING MEANING FROM DNA SEQUENCE DATA USING NATURAL LANGUAGE PROCESSING (NLP)
US 05.05.2022
Int.Class G16B 40/00
GPHYSICS
16INFORMATION AND COMMUNICATION TECHNOLOGY SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
40ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
Appl.No 17088734 Applicant BASF CORPORATION Inventor Erin Marie Davis

Apparatuses, systems, and methods are provided that may analyze deoxyribonucleic add (DNA) sequence data using a natural language processing (NLP) model to, for example, identify genetic elements such as known and/or novel cis-regulatory elements (e.g., known and/or putative novel drought-responsive cis-regulatory elements (DREs)). Apparatuses, systems, and methods are also provided that may identify transcriptional regulators (e.g., upstream transcriptional regulators of a novel putative DRE) based on natural language processing (NLP) model data and expression genome-wide association study (eGWAS) data. Apparatuses, systems, and methods are also provided that may verify putative novel cis-regulatory elements based on a comparison of natural language processing (NLP) model output data and other model output data.

4.20240071569APPARATUSES, SYSTEMS, AND METHODS FOR EXTRACTING MEANING FROM DNA SEQUENCE DATA USING NATURAL LANGUAGE PROCESSING (NLP)
US 29.02.2024
Int.Class G16B 40/00
GPHYSICS
16INFORMATION AND COMMUNICATION TECHNOLOGY SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
40ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
Appl.No 18034417 Applicant BASF CORPORATION Inventor Erin Marie Davis

Apparatuses, systems, and methods are provided that may analyze deoxyribonucleic add (DNA) sequence data using a natural language processing (NLP) model to, for example, identify genetic elements such as known and/or novel cis-regulatory elements {e.g., known and/or putative novel drought-responsive cis-regulatory elements (DREs)). Apparatuses, systems, and methods are also provided that may identify transcriptional regulators {e.g., upstream transcriptional regulators of a novel putative DRE) based on natural language processing (NLP) model data and expression genome-wide association study (eGWAS) data. Apparatuses, systems, and methods are also provided that may verify putative novel cis-regulatory elements based on a comparison of natural language processing (NLP) model output data and other model output data.

5.WO/2022/098588APPARATUSES, SYSTEMS, AND METHODS FOR EXTRACTING MEANING FROM DNA SEQUENCE DATA USING NATURAL LANGUAGE PROCESSING (NLP)
WO 12.05.2022
Int.Class C12Q 1/68
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
Appl.No PCT/US2021/057491 Applicant BASF CORPORATION Inventor DAVIS, Erin, Marie
Apparatuses, systems, and methods are provided that may analyze deoxyribonucleic add (DNA) sequence data using a natural language processing (NLP) model to, for example, identify genetic elements such as known and/or novel cis-regulatory elements {e.g., known and/or putative novel drought-responsive cis-regulatory elements (DREs)). Apparatuses, systems, and methods are also provided that may identify transcriptional regulators {e.g., upstream transcriptional regulators of a novel putative DRE) based on natural language processing (NLP) model data and expression genome-wide association study (eGWAS) data. Apparatuses, systems, and methods are also provided that may verify putative novel cis-regulatory elements based on a comparison of natural language processing (NLP) model output data and other model output data.
6.WO/2018/017467DISTRIBUTED MACHINE LEARNING SYSTEMS, APPARATUS, AND METHODS
WO 25.01.2018
Int.Class G06N 99/00
GPHYSICS
06COMPUTING; CALCULATING OR COUNTING
NCOMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
99Subject matter not provided for in other groups of this subclass
Appl.No PCT/US2017/042356 Applicant NANTOMICS, LLC Inventor SZETO, Christopher
A distributed, online machine learning system is presented. Contemplated systems include many private data servers, each having local private data. Researchers can request that relevant private data servers train implementations of machine learning algorithms on their local private data without requiring de-identification of the private data or without exposing the private data to unauthorized computing systems. The private data servers also generate synthetic or proxy data according to the data distributions of the actual data. The servers then use the proxy data to train proxy models. When the proxy models are sufficiently similar to the trained actual models, the proxy data, proxy model parameters, or other learned knowledge can be transmitted to one or more non-private computing devices. The learned knowledge from many private data servers can then be aggregated into one or more trained global models without exposing private data.
7.2017300259Distributed machine learning systems, apparatus, and methods
AU 25.01.2018
Int.Class G06N 99/00
GPHYSICS
06COMPUTING; CALCULATING OR COUNTING
NCOMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
99Subject matter not provided for in other groups of this subclass
Appl.No 2017300259 Applicant Nant Holdings IP, LLC Inventor Benz, Stephen Charles
A distributed, online machine learning system is presented. Contemplated systems include many private data servers, each having local private data. Researchers can request that relevant private data servers train implementations of machine learning algorithms on their local private data without requiring de-identification of the private data or without exposing the private data to unauthorized computing systems. The private data servers also generate synthetic or proxy data according to the data distributions of the actual data. The servers then use the proxy data to train proxy models. When the proxy models are sufficiently similar to the trained actual models, the proxy data, proxy model parameters, or other learned knowledge can be transmitted to one or more non-private computing devices. The learned knowledge from many private data servers can then be aggregated into one or more trained global models without exposing private data.
8.3031067DISTRIBUTED MACHINE LEARNING SYSTEMS, APPARATUS, AND METHODS
CA 25.01.2018
Int.Class G06N 99/00
GPHYSICS
06COMPUTING; CALCULATING OR COUNTING
NCOMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
99Subject matter not provided for in other groups of this subclass
Appl.No 3031067 Applicant NANTOMICS, LLC Inventor SZETO, CHRISTOPHER
A distributed, online machine learning system is presented. Contemplated systems include many private data servers, each having local private data. Researchers can request that relevant private data servers train implementations of machine learning algorithms on their local private data without requiring de-identification of the private data or without exposing the private data to unauthorized computing systems. The private data servers also generate synthetic or proxy data according to the data distributions of the actual data. The servers then use the proxy data to train proxy models. When the proxy models are sufficiently similar to the trained actual models, the proxy data, proxy model parameters, or other learned knowledge can be transmitted to one or more non-private computing devices. The learned knowledge from many private data servers can then be aggregated into one or more trained global models without exposing private data.
9.20220405644Distributed machine learning systems, apparatus, and methods
US 22.12.2022
Int.Class G06N 20/00
GPHYSICS
06COMPUTING; CALCULATING OR COUNTING
NCOMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
20Machine learning
Appl.No 17890953 Applicant NantOmics, LLC Inventor Christopher W. Szeto

A distributed, online machine learning system is presented. Contemplated systems include many private data servers, each having local private data. Researchers can request that relevant private data servers train implementations of machine learning algorithms on their local private data without requiring de-identification of the private data or without exposing the private data to unauthorized computing systems. The private data servers also generate synthetic or proxy data according to the data distributions of the actual data. The servers then use the proxy data to train proxy models. When the proxy models are sufficiently similar to the trained actual models, the proxy data, proxy model parameters, or other learned knowledge can be transmitted to one or more non-private computing devices. The learned knowledge from many private data servers can then be aggregated into one or more trained global models without exposing private data.

10.WO/2022/155555SYSTEMS AND METHODS FOR DERIVING HEALTH INDICATORS FROM USER-GENERATED CONTENT
WO 21.07.2022
Int.Class G16H 50/20
GPHYSICS
16INFORMATION AND COMMUNICATION TECHNOLOGY SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
50ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
20for computer-aided diagnosis, e.g. based on medical expert systems
Appl.No PCT/US2022/012645 Applicant MY LUA LLC Inventor CONWARD, Michael
The present disclosure relates to systems and methods for generating priority lists and/or predictions or identifications of root causes of acute or chronic conditions. In one exemplary embodiment, a method comprises aggregating data corresponding to a plurality of individuals, the data comprising, for each individual, user-generated content and/or biometric data; generating, from a machine learning model that utilizes the aggregated user-generated content and/or biometric data as input, one or more of a priority list for the plurality of individuals, or, for each individual, a prediction, diagnosis, or identification of one or more root causes of one or more acute or chronic conditions of the individual.