Described herein are compounds that are estrogen receptor modulators. Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such estrogen receptor modulators, alone and in combination with other compounds, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.

The proposed invention relates to the field of power engineering and makes it possible to provide highly efficient electrical power generation in extreme weather conditions. A system for controlling electrical power generation is proposed which comprises power generating units that are connected to a network via a parallel circuit and comprise a power house, an electrical generator, switches and programmable control and protection means. At least one active loading device is connected to the electrical network in parallel with the power generating units. The programmable control and protection means include a microprocessor-based excitation system with an insulated gate bipolar transistor converter, an automatic gain control controller and an electrical generator differential protection controller. The controllers are connected to one another and to the microprocessor-based excitation system, the switches and a station computer for controlling the power generating units, said station computer being the end point in a two-way wireless communication link with a dispatch computer for remotely controlling and monitoring the power generating units.

The invention relates to methods for producing carbon dioxide chemical adsorbent which is based on hydroxides of alkali and/ or alkali-earth metals and can be used in means for protecting respiratory organs. The method for producing carbon dioxide chemical adsorbent for respiratory systems involves combining alkali and/ or alkali-earth metal hydroxides with a fibrous material, shaping adsorbent in the form of a sheet and drying it. The alkali and/or alkali-earth metal hydroxides are used in the form of an aqueous dispersion and the alkali and/ or alkali-earth metal hydroxides is combined with the fibrous material by accommodating the aqueous dispersion between the layers of a porous fibrous material. The alkali and/or alkali-earth metal hydroxides such as potassium hydroxide, sodium hydroxide, lithium hydroxide, calcium hydroxide, magnesium hydroxide and the similar hydroxides chemically active to carbon dioxide can be used as metal hydroxides. The aqueous dispersion can be of a paste or suspension consistency or in the form of a solution. The following materials can be used as a porous fibrous material: fibre paper, glass-fiber mat, heat resistant non-flammable materials such as Nomex, Kevlar (Du Pont, USA), Rusar and Arselon (Russia) and any other alkali-proof low specific density materials. The invention makes it possible to increase by 20-40% the reaction capacity of the adsorbent, thereby extending the possibilities of using it in systems for removing carbon dioxide from air, the adsorbent production method being technologically simple.

The invention relates to the field of genetic engineering and can be used in the treatment of diseases associated with the human papillomavirus. The mucosal vaccine contains, in an effective amount, a hybrid protein consisting of the human papillomavirus oncoprotein E7 fused with the mycobacterial heat shock protein Hsp70, chitosan in a ratio with the hybrid protein of 1:0.1-10, and pharmacologically acceptable additives for the manufacture of suppositories. The proposed invention makes it possible to increase by many times the effectiveness of the treatment of diseases associated with the human papillomavirus, significantly reduce the cost of treatment compared to known methods for treating cervical cancer and rectal cancer, eliminate undesirable and life-threatening side effects to the patient of injection preparations, for example anaphylactic shock, due to topical application, and simplify the treatment process since the patient can carry out the course of treatment as an outpatient, administering the preparation independently.

The invention relates to the field of electronic engineering and can be used in electrical equipment. The separable electrical contact connection comprises contact elements, the current-conducting surfaces of which are coated with a gallium-based alloy having the following composition in weight percent: 64-99.9999 gallium, 0.001-35 indium, 0.001-28 tin, 0.001-7.5 silver, 0.001-5 cadmium, 0.001-25 zinc, 0.0001-10 copper and 0.0001-12 aluminium. A method for processing contact surfaces involves etching said contact surfaces to remove an oxide film using a first etchant, subsequently neutralizing said etchant and cleaning the surfaces to remove the etching products, mechanically cleaning the surfaces by polishing, heating the contact surfaces within a range of 10-70ºC and applying the gallium alloy in the medium of a second solution, the remainder of which is neutralized once processing is complete. The invention makes it possible to improve the quality of preparation of a contact surface in order to produce a reliable separable electrical contact connection while increasing the load-carrying capacity thereof and providing for stable electrical transition resistance characteristics during use.