The invention concerns a method for the production of nitrate containing products (fertilizers, technical products) from undercooling melts, wherein a XN - water solution is evaporated up to a content of 50-99.8 weight % XN, where X is one or more selected from Ca, Mg, NH4, Na and K, and N means nitrate. The preferred range of XN is 70-99.5 weight %. The melt is cooled down to and kept at a temperature at or below the crystallisation point and finely divided solid XN powder consisting of the equilibrium phases is added to the melt. Melt drops are then formed and allowed to cool and solidify during up to 70 seconds. It is preferred to use a cooling belt for solidification of the particles. The belt is cooled by air, water, oil or another medium.

Intermediates represented by the following general formula (I), etc. which are useful in producing phenoxyacetic acid derivatives represented by the following general formula (X) or pharmaceutically acceptable salts thereof having an effect of stimulating β3-adrenalin receptor and being useful as preventives or remedies for obesity, hyperglycemia, diseases caused by enteric movement disorders, urinary frequency, urinary incontinence, depression or biliary calculus; a process for producing these intermediates; and a method of using the same: (I) (X) wherein R1 and R2 independently represent each lower alkyl.

The doubly prestressed roof-ceiling construction with grid flat soffit for extremely large-span is prefabricated element intended for assembling roofs of extremely large-span buildings with flat soffit. The construction comprises the grid soffit construction (1) and the upper concrete girder (2) of a modified 'T' shaped or of an inverse 'V' shaped cross section, interconnected by slender steel pipe-rods (3) that stabilize the upper girder (2) against lateral buckling. The empty openings within elements of the horizontal grid (1) are fulfilled with plates (6) wherewith a flat soffit is achieved. The construction is prestressed by the double prestressing. The grid-soffit (1) is prestressed centrically and the upper girder (2) is prestressed by the wedge (5) at the midspan.

The method and process for producing youthful appearing, small-pored, and smooth skin comprises pretreating the skin topically with retinoic acid, applying a contaminate in oil to the skin, and removing the contaminate by exploding or rupturing it with laser light. When treating the face, removing the contaminate requires only about 4 minutes. The laser light itself does not injure the skin but the rupture of the contaminant produces thermal injury in the high dermis leaving the epidermis intact. Repeated intermittent laser treatments and applications of topical retinoic acid produces the desired results in the skin indefinitely as long as the treatments and applications are continued.

The indirectly prestressed concrete roof-ceiling construction is prefabricated element for constructing industrial large-span buildings. The construction comprises distinctly wide and thin concrete soffit plate (1) and upper concrete girder (2), of the inverse 'V'-shaped cross section, interconnected by slender steel pipe-rods (3) that are used to stabilize the upper girder (2) against lateral buckling and to prevent parts (1) and (2) to get closer or apart each to another. Prestressing of the soffit plate (1) causes compression in the upper girder (2) which passively (indirectly) pushes the ends of the construction, acting on some eccentricity over the center of gravity of the cross section, causing rotation of its ends bending in that way the soffit plate upwards. There are two efficient methods of prestressing these constructions.

The present invention relates to a composition comprising a catechin compound, ascorbic acid, proline and lysine. The present invention also relates to a method for treating neoplastic disease using a composition comprising a catechin compound, ascorbic acid, proline and lysine.

This invention concerns compositions of estrogen and related hormones in combination with ascorbate, lysine, proline and other substances effecting connective tissues, their ability and their use in contraception, hormonal replacement therapy during menopause, and for other use in medicine, physiology, pharmacology, pharmaceuticals and cosmetic application.

The present invention relates to novel stable solution formulations comprising oxaliplatin, an effective stabilizing amount of lactic acid and/or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable carrier. A method for manufacturing such formulations ready for administration and their use in the antitumor therapy are also within the scope of the invention.

Pharmaceutical compositions effective in alleviating or reducing the effects of fatigue and weakness associated with cancer and cytotoxic cancer chemotherapy are disclosed. The pharmaceutical compositions of the present invention comprise riboflavin, effectors of the urea cycle in free form or pharmacologically acceptable salts thereof, and amino acids selected from the gorups of essential and non-essential amino acids, in free form or pharmaceutically acceptable salts thereof, suitably combined with appropriate carriers, diluents, or excipients. Also disclosed are methods of alleviating or reducing the effects of fatigue and weakness associated with cancer and cytotoxic cancer chemotherapy by administration of pharmaceutical compositions of the present invention.

The invention relates to a rotor (10) with a rotor spider (11) which rotates about an axis, comprising a number of webs (12) and a laminated rim (14), made from individual rim sheets (16), concentrically surrounding the rotor spider (11) and connected to the rotor spider (11), by means of taper keys (13) in a laminated rim keyway. A simplified connection of laminated rim (14) to rotor spider (11) is achieved, whereby the keys (13) and the laminated sheets (16) are embodied such as to engage by forming a rigid positive fit.