A nebulizer (1) is proposed which comprises an insertable container (3) and a counter device (23) for counting operations of the nebulizer. The nebulizer can be opened for replacing the container. A securing device (32) having locking portions (33b) forcing apart is provided to prevent reconnection of an already used container. The nebulizer shows the current container number and alternately symbols indicating container replacement. An indicator member (50) is driven by the force of an internal spring (20). The indicator member controls also a lock (57) of the container for locking the container against further actuation. The lock is resetted after container replacement.

The invention relates to a method for physically working and/or heating media, in particular liquids. The high expenditure of energy of the known methods can be avoided, with reduced environmental impact, by the hydrodynamically worked medium being exposed to polar and/or ionic electrochemical potentials and electrochemical signals RC AC.

The present invention relates to a system (1) and method (100) which enables the SMSs to be sent encrypted and to be opened only in the mobile devices (2), wherein the SIM card belonging to the MSISDN, to which they are sent, is installed. The inventive system (1) comprises a mobile device (2) which can run mobile application and in which a SIM card can be installed, a content sender (3) which sends the confidential information of its clients via SMS, a database (4) wherein the encryption keys produced specific to the SIM card by the SIM card producer are stored, an SMSC (5) which transmits the information it receives to the mobile device (2), an encryption platform (6) which encrypts the SMS that will be sent, and an OTP sending platform (7) which receives the SMS content from the content sender (3), sends it to the encryption platform (6) and sends the encrypted SMS it receives from the encryption platform (6) to the SMSC (5).

The present invention provides a mixed crystal agomelatine (Form-VIII), the preparation method and use thereof and a pharmaceutical composition containing the same, wherein the mixed crystal mainly contains an agomelatine crystal form VI. The mixed crystal is stable and has good reproducibility, and is found through a stability test to be superior to a crystal form VI in terms of stability. Therefore, the Form-VIII of the present invention has an advantage in terms of preparation.

The present invention provides a new crystal form VII of agomelatine, the preparation method and use thereof and a pharmaceutical composition containing the same. The new crystal form has a good purity, a stable crystal form and good reproducibility; the preparation method thereof is easy to amplify; and it is superior to most previously reported crystal forms in terms of stability and solubility. Therefore, the crystal form VII of the present invention has an advantage in terms of preparation.

A piece (5) is set in a required orientation via rotations about at least two mutually transverse axes (52, 57), on the basis of the differences between the required orientation and the position represented in a captured image while the piece (5) is arriving on a resting plane (29), and on the basis of the outcome of a comparison between the data of the captured image and the data stored of images that show a sample element equal to the piece (5) to be transferred and set in respective different stable resting positions.

The invention relates to a novel use of the antimuscarinic agent glycopyrrolate, for example the salt glycopyrronium bromide. In particular, the invention relates to glycopyrrolate for use as a heart rate lowering agent and more particularly, but not exclusively, for use in patients suffering from respiratory conditions such as chronic obstructive pulmonary disease.

A device for closing containers (C) including a first (CI) and a second (C2) vat-shaped half-shell and to be coupled with their respective mouth portions in a frontal mating relationship (C12) as a result of a turnover movement leading the second half-shell (C2), initially arranged sideways of the first half-shell (CI), to overturn closing onto the first half-shell (CI). The device includes a support body (12) with a holder structure (14) for receiving the first half- shell (CI) of one of the containers (C) with the second half-shell (C2) hinged (C3) to the first half-shell (CI) and protruding from one side of the support body (12), as well a turnover element (112) with at least one pusher member (120) selectively actuatable to advance towards the support body (12) for imparting to the second half-shell (C2) the aforementioned turnover closing movement.

A device for inserting sheet-like elements (F) in respective containers (C) including: - first pick-up members (12) for picking up the sheet-like elements (F) in a flat condition, a transfer device (16) including reception cavities (164) wherein the first pick-up members (12) insert the sheet-like elements (F) carried thereby in a flat condition allowing them to take a U-shape as a result of being inserted in the reception cavities (164), and - second pick-up members (200) with a finger-like shape adapted to be inserted in the reception cavities (164) for picking up the sheet-like elements (F) and insert them in respective containers (C).

At present, many herbicidal compositions have been developed and used, but there are a variety of types of weeds to be controlled, and their development lasts for a long period of time. Thus, a high active and long-residual herbicidal composition having a broad herbicidal spectrum has been desired. The present invention provides a synergistic herbicidal composition comprising (A) flazasulfuron or its salt and (B) at least one urea compound selected from the group consisting of tebuthiuron, diuron and metobromuron or its salt. According to the synergistic herbicidal composition of the present invention, a high active and long-residual herbicidal composition having a broad-spectrum can be provided.