WO/2015/130222 ANTIBODY PURIFICATION PROCESS||WO||03.09.2015|
||PCT/SG2014/000086||AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH||GAGNON, Peter Stanley|
A method of purifying a target antibody includes contacting a cell culture harvest or a protein preparation including at least one target antibody with at least one fatty acid having 7 to 10 carbon atoms to form a mixture, contacting this mixture with allantoin, and then separating solid materials to provide a solution comprising the target antibody. Solid materials can be removed by filtration, sedimentation or centrifugation, and the fatty acids can be enanthic, caprylic, pelargonic, nonenoic or capric acid. The invention is also directed to kits used to facilitate this method of antibody purification.
WO/2015/130223 METHODS FOR REDUCING CHROMATIN CONTENT IN PROTEIN PREPARATIONS BY TREATMENT WITH ALKYL CATIONS||WO||03.09.2015|
||PCT/SG2014/000087||AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH||GAGNON, Peter Stanley|
A method of reducing aggregate content in a preparation having a target protein includes contacting the preparation with an alkyl cation to form a mixture, and contacting the mixture with at least one functionalized solid to remove excess alkyl cation.
WO/2015/130221 METHODS FOR REDUCING AGGREGATE CONTENT OF PROTEIN PREPARATIONS BY TREATMENT WITH ARYL ANIONS||WO||03.09.2015|
||PCT/SG2014/000085||AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH||GAGNON, Peter Stanley|
A method of reducing the aggregate content in a preparation having a target protein includes contacting the preparation with an aryl anion to form a mixture and contacting the mixture with at least one electropositive solid to remove excess aryl anion.
WO/2015/130224 A COMPUTER IMPLEMENTED METHOD AND PLATFORM FOR MERGING AT LEAST TWO ANIMATED WORK PRODUCTS||WO||03.09.2015|
||PCT/SG2014/000096||TOOOOON PTE LTD||HO, Wei Siong|
There is provided a computer implemented method and platform for merging at least two animated work products. The method includes creating a first animated work product at a storage and viewing portal on at least one server; creating a second animated work product at the storage and viewing portal; merging the first animated work product and the second animated work product in a desirable manner to create a third animated work product at the storage and viewing portal; and providing a list of contributors for the third animated work product, the list of contributors including a creator for each of the first, and the second animated work products. The platform facilitates the carrying out of the aforementioned method.
WO/2015/130225 URINALYSIS DEVICE AND DRY REAGENT FOR QUANTITATIVE URINALYSIS||WO||03.09.2015|
||PCT/SG2014/000269||NITTO DENKO CORPORATION||CHEN, Xiaojun|
There is disclosed herein a method of quantitatively determining the concentration of at least one analyte in a sample, the method comprising the steps of either: (i) adding a portion of the sample to a first analyte assay formulation and to an analyte assay reference formulation to generate a first analyte sample and analyte reference sample and determining the concentration of the at least one analyte in the sample and/or (ii) adding a portion of the sample to a second analyte assay formulation and determining the concentration of the at least one analyte in the sample. Also disclosed herein are formulations, kits of parts, systems and computer implemented methods associated with said method.
WO/2015/130235 BUCK-BOOST POWER AMPLIFIER WITH INDEPENDENTLY CONTROLLED POWER STAGES AND COMPENSATED NONLINEAR PULSE WIDTH MODULATOR||WO||03.09.2015|
||PCT/SG2015/050027||AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH||YU, Jun|
A buck-boost power amplifier receiving a supply voltage and providing an output having a voltage swing higher than the supply voltage is provided. The buck-boost power amplifier comprises a buck power stage, a boost power stage, an inductor, and a non-linear pulse width modulator. The buck power stage and the boost power stage are independently controlled by the non-linear pulse width modulator. The non-linear pulse width modulator switches the buck-boost power amplifier between a buck mode wherein the output provides a voltage lower than the supply voltage and a boost mode wherein the output provides a voltage higher than the supply voltage.
WO/2015/130232 MASSAGE CHAIR AND METHOD OF DRIVING THE SAME||WO||03.09.2015|
||PCT/SG2015/000063||OSIM INTERNATIONAL LTD||TAN, Kia Tong|
A massage chair includes a backrest, and two sets of massage arms assembled with the backrest and spaced apart from each other along a transversal axis of the backrest, each set including a first and a second massage arm that respectively have a first and a second contact member and are movable relative to each other. The method includes positioning the two sets of the massage arms such that at least the first contact members of the first massage arms contact a desired region of a user's body, actuating the two sets of the massage arms to perform a sequence of kneading pulses or a continuous kneading displacement from a wide state to a narrow state to apply a gripping action on the user's body, and stopping the two sets of the massage arms in the narrow state for a period of time to maintain the gripping action on the user's body.
WO/2015/130231 SEGMENTATION OF CARDIAC MAGNETIC RESONANCE (CMR) IMAGES USING A MEMORY PERSISTENCE APPROACH||WO||03.09.2015|
||PCT/SG2015/000062||AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH||YANG, Xulei|
A method is proposed for identifying an anatomical structure within a spatial-temporal image (i.e. a series of frames captured as respective times). A current frame of spatial- temporal medical image is processed using information from one or more previous and/or subsequent temporal frames, to aid in the segmentation of an object or a region of interest (ROI) in a current frame. The invention is applicable to both two- and three-dimensional spatial-temporal images (i.e., 2D + time or 3D + time), and in particular to cardiac magnetic resonance (CMR images). An initialisation process for this method segments the left ventricle (LV) in a CMR image by a fuzzy c-means (FCM) clustering algorithm which employs a circular shape function as part of the definition of the dissimilarity measure.
WO/2015/130230 AN IN SITU REAL TIME MONITORING SYSTEM FOR TRACE ANALYTES IN WATER||WO||03.09.2015|
||PCT/SG2015/000061||NATIONAL UNIVERSITY OF SINGAPORE||LI, Weijia|
There is disclosed a preconcentration device for measuring the amount of a trace analyte in a water body, the device comprising a vessel having an opening, a hydrated polymer membrane that covers the opening in the vessel, an aqueous solution of a polyelectrolyte polymer provided in the vessel and in direct contact with the membrane. There is also disclosed the use of an aqueous solution of a polyelectrolyte polymer to detect an analyte and a method of analysing the amount of a trace analyte in a water body.
WO/2015/130228 CATHODE MATERIALS CONTAINING OLIVINE STRUCTURED NANOCOMPOSITES||WO||03.09.2015|
||PCT/SG2015/000057||NANYANG TECHNOLOGICAL UNIVERSITY||YAZAMI, Rachid|
The invention relates to cathode materials containing olivine structured nanocomposites for lithium batteries. In particular, the olivine structured nanocomposites include a mixture of lithium metal phosphates.