WO/2016/132343 PROCESS AND INTERMEDIATES FOR THE PREPARATION OF PERAMPANEL||WO||25.08.2016|
||PCT/IL2015/050180||MAPI PHARMA LTD.||MAROM, Ehud|
The present invention describes a process for the synthesis of 3-(2-cyanophenyl)-5-(2- pyridyl)-1-phenyl-1,2-dihydro-pyridin-2-one (Perampanel) represented by the structure of formula (1), and salts thereof, especially salts with pharmaceutically acceptable acids. The present invention further relates to certain intermediates formed and/or used in such process.
WO/2016/132351 POE POWER UTILIZATION ARRANGEMENT AND METHOD||WO||25.08.2016|
||PCT/IL2016/050176||MICROSEMI CORP. - ANALOG MIXED SIGNAL GROUP, LTD.||DARSHAN, Yair|
A PoE power utilization method constituted of: detecting a first function of a voltage between a current path node (20) and a current return path node (30) during a first time period and during a second time period, the second time period different than the first time period; sensing a second function of the magnitude of a current flowing through the current path (70) during the second time period; responsive to the detected first time period voltage function, the detected second time period voltage function and the sensed second time period current magnitude function, determining a third function of a resistance seen by the current path (70); and outputting an indication of the determined resistance function.
WO/2016/132349 TRANSIENT BRAGG GRATINGS IN OPTICAL WAVEGUIDES AND THEIR APPLICATIONS||WO||25.08.2016|
||PCT/IL2016/050171||B. G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD., AT BEN-GURION UNIVERSITY||ISHAAYA, Amiel|
A method for obtaining transient Bragg gratings in optical waveguides and several different applications of the transient Bragg gratings obtained using this method are presented. The basic mechanisms for obtaining the transient gratings in the waveguides are refractive index change due to Kerr nonlinearity, free carrier generation, and gratings formed by linear or non-linear absorption of thermal energy. The exemplary applications include an ultra-fast fiber laser source at any central wavelength, a fast spectral switch/modulator, transient pulse stretchers based on transient chirped gratings, Q-switching based on transient gratings, and time reversal of ultra-short pulses and low power sub-nanosecond pulse generations.
WO/2016/132348 HEAVY-DUTY FOLDABLE STORAGE BIN||WO||25.08.2016|
||PCT/IL2016/050165||DOLAV PLASTIC PRODUCTS COOPERATIVE SOCIETY LTD.||MALLAN, Lee|
A heavy-duty, thermoplastic storage bin comprises a rectilinear base, spaced columns integrally formed with the base, and rectangular end and side panels that are foldable and erectable with respect to the base. At least one of the panels is detachable from the base. At least one central column having an integral portion protrudes upwardly from an upper base surface and is interlockable with a corresponding side panel at a bottom center region, for generating a sufficiently high sagging resisting moment. In a method for emptying the bin, the base is supported by a forklift, after the bin has been loaded with desired products. Following a material handling operation by the forklift, a tilting device carried by the forklift is operated to sufficiently change a disposition of the bin such that the loaded products are caused to be emptied while a side panel remains engaged with the central and corner columns.
WO/2016/132362 POWER CONTACT ASSEMBLY FOR A TRACK LIGHTING SYSTEM||WO||25.08.2016|
||PCT/IL2016/050190||CHOCOLATE LIGHTING COMPANY LTD||TUCHLER, Gideon|
A power contact assembly for use with a system comprising track-mounted luminaires and track is disclosed. In some embodiments, electrical power for illumination is accessed by a luminaire through a power contact assembly in contact with an electrified railing recessed within a relatively narrow slot of the track. In some embodiments, mounting means are provided separately from and/or additional to the interaction of the power contact assembly with the power slot, comprising, for example, a magnetic mount. The track is optionally mounted flush and/or recessed with a mounting surface such as a ceiling and/or wall. In some embodiments, a recessed surface of the track is formed with an arc. Optionally luminaires conform with the curvature of the arc. Additionally or alternatively, the track is at least partially masked and/or decorated, for example by plastering and/or a face plate.
WO/2016/132369 A CAPSULE FOR STORING A SUBSTANCE IN A DISPOSABLE CUP AND USES THEREOF||WO||25.08.2016|
||PCT/IL2016/050197||AMSEL, Haim, Simcha||AMSEL, Haim, Simcha|
The present invention provides a capsule for enclosing a substance on a bottom of a first disposable cup comprising a bottom and a rim deformed from the bottom of the first cup, the capsule comprising: a bottom having a circumference; a wall extending from the circumference; and an opening, wherein the capsule is configured to be accommodated in a space defined by the bottom and the rim of a second disposable cup inserted inside the first disposable cup. The capsule may further comprise at least one handle and at least one inner wall. Furthermore the present invention provides a method for packaging a plurality of disposable cup, capsules and substance in a manner that keeps the substance fresh for an extended period of time.
WO/2016/132370 HIGH-AMYLOSE STARCH- FORMATE ELECTROSPUN FIBERS||WO||25.08.2016|
||PCT/IL2016/050201||NANOSPUN TECHNOLOGIES LTD.||ZUSSMAN, Eyal|
Starch-based fibers, compositions comprising same, method of preparing said starch-based fibers, kits and methods for use of said starch-based fibers including but not limited to oral delivery of cells (e.g., probiotic microorganisms) and/or molecules of interest (e.g., nutrients) are provided.
WO/2016/132366 COMBINATION IMMUNE THERAPY AND CYTOKINE CONTROL THERAPY FOR CANCER TREATMENT||WO||25.08.2016|
||PCT/IL2016/050194||ENLIVEX THERAPEUTICS LTD.||NOVIK, Shai|
Compositions disclosed herein, and methods of use thereof included those for inhibiting or reducing the incidence of cytokine release syndrome or cytokine storm in a subject undergoing CAR T-cell therapy, wherein the subjects are administered compositions including apoptotic cells or apoptotic cell supernatants. In certain instances compositions and methods of use thereof disclosed herein do not reduce the efficacy of the CAR T-cell cancer therapy. Disclosed herein are also compositions and methods of use thereof for decreasing or inhibiting cytokine production in a subject experiencing cytokine release syndrome or cytokine storm including administration of a composition including apoptotic cells or an apoptotic cell supernatant.
WO/2016/132350 A-FRAME LADDER WORKING AID KIT||WO||25.08.2016|
||PCT/IL2016/050172||WISSE, Yossef||WISSE, Yossef|
In one aspect, the present invention is directed to a working aid kit for an A-framed ladder (11), the kit comprising: a removable seat (12), to be placed on a top of the ladder; adjustable seat connecting means (21), for connecting and securing the seat to a step of the ladder; a removable tool tray (14), attachable to the removable seat; and tool tray connecting means (50, 52), for connecting the tray to the seat (12) such that the tool tray (14) being situated symmetrically on a symmetry axis (16) passing through the pivots connecting the rails (10) of the ladder (1 1 ), in front of a user sitting on the seat such that each of his legs lean on a different step of the ladder; thereby providing comfort and safety for a worker sitting on the ladder.
WO/2016/132352 BREAST IMPLANTS||WO||25.08.2016|
||PCT/IL2016/050178||IMPLITE LTD.||GLICKSMAN, Ami|
There is provided herein a breast implant comprising: an internal skeleton element comprising a base configured to face a subject's chest wall when implanted, a dome configured to face a subject's nipple-areola complex when implanted, and a projecting structure extending between the base and the dome; and a shell enclosing the internal skeleton element and filled with a filler substance. The breast implant is configured to be inserted into a sub-glandular plane, a sub-muscular plane or a subcutaneous plane of a subject's breast, to affect the projection and volume of the breast.