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Analysis

1 / 1
1.WO/2024/153953mRNA COMPOSITIONS
WO - 25.07.2024
Int.Class A61K 39/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
12Viral antigens
 Appl.No PCT/GB2024/050155 Applicant SISAF LTD Inventor SAFFIE-SIEBERT, Roghieh Suzanne
Disclosed is an mRNA vector composition, comprising: mRNA; one or more particles comprising hydrolysable silicon; and one or more lipids, characterised in that the mRNA is mRNA which is not chemically modified. Also disclosed are related products, methods and uses.
2.118019981用于表征肿瘤的方法
CN - 10.05.2024
Int.Class G01N 33/574
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
574for cancer
 Appl.No 202280065175.3 Applicant 蒙彼利埃大学医疗中心 Inventor 埃里克·里瓦尔
本发明涉及用于表征肿瘤的体外方法，该方法基于对从生物样品中提取的细胞总RNA、细胞外RNA和/或分离的核苷中修饰和未修饰的核苷的定量分析。更具体地，本发明涉及用于预测神经胶质肿瘤等级的方法。更具体地，本发明还涉及用于检测肿瘤的方法。因此，本发明属于肿瘤学和分子生物学领域，更具体地应用于医学诊断。
3.1020240035609종양을 특성화하기 위한 방법
KR - 15.03.2024
Int.Class G01N 33/574
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
574for cancer
 Appl.No 1020247006194 Applicant 상트르 하스피탈리에 유니베르시테르 드 몽펠리에 Inventor 라이벌즈 에릭
본 발명은 생물학적 샘플로부터 추출된 전체 세포 RNA, 세포 외 RNA 및/또는 단리된 뉴클레오시드로부터의 변형 및 비변형 뉴클레오시드의 정량적 분석을 기반으로 종양을 특성화하기 위한 시험관 내 방법에 관한 것이다. 보다 구체적으로, 본 발명은 신경교 종양의 등급을 예측하기 위한 방법에 관한 것이다. 더 구체적으로, 본 발명은 또한 종양을 검출하기 위한 방법에 관한 것이다. 따라서, 본 발명은 특히 의학적 진단에 적용되는 암종학 및 분자생물학 분야에 속한다.
4.WO/2023/183569METHODS AND APPARATUS FOR SYNTHESIZING NUCLEIC ACIDS
WO - 28.09.2023
Int.Class C12N 15/11
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
11DNA or RNA fragments; Modified forms thereof
 Appl.No PCT/US2023/016226 Applicant MOLECULAR ASSEMBLIES, INC. Inventor HOPKINS, Patrycja A.
Methods for the synthesis of polynucleotides using polymerases nucleotide analogs with labile terminator groups that allow stepwise addition of nucleotides are described. These nucleotide analogs may have a modification on 3', 2', or 3'-2'- bridged hydroxyl groups or on nucleobase moieties and can be used in the synthesis of natural or modified polynucleotides suitable for use in biological systems. The labile terminator groups are removed under mild conditions or by enzymes. They are accepted as substrates by polymerases. The synthesis may be carried out on a surface.
5.WO/2023/118456SYNTHETIC TRANSFER RNA WITH MODIFIED NUCLEOTIDES
WO - 29.06.2023
Int.Class C12N 15/11
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
11DNA or RNA fragments; Modified forms thereof
 Appl.No PCT/EP2022/087512 Applicant UNIVERSITÄT HAMBURG Inventor IGNATOVA, Zoya
The invention relates to a synthetic transfer RNA with at least one modified nucleotide or combination of modified nucleotides at a unique position or a unique pattern of modified nucleotides.
6.4202045SYNTHETIC TRANSFER RNA WITH MODIFIED NUCLEOTIDES
EP - 28.06.2023
Int.Class C12N 15/11
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
11DNA or RNA fragments; Modified forms thereof
 Appl.No 21216959 Applicant UNIV HAMBURG Inventor IGNATOVA ZOYA
The invention relates to a synthetic transfer RNA with at least one modified nucleotide or combination of modified nucleotides at a unique position or a unique pattern of modified nucleotides.
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