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Analysis

1 / 19
1.20250304669RGMC-SELECTIVE INHIBITORS AND USE THEREOF
US - 02.10.2025
Int.Class C07K 16/18
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
 Appl.No 19178027 Applicant SCHOLAR ROCK, INC. Inventor Samantha NICHOLLS

Selective inhibitors of repulsive guidance molecule C (RGMc), are described. Related methods, including methods for making, as well as therapeutic use of these inhibitors in the treatment of disorders, such as anemia, are also provided.

2.WO/2025/207985COMPOUNDS, COMPOSITIONS, AND METHODS OF TREATING RNA VIRAL INFECTIONS
WO - 02.10.2025
Int.Class A61K 31/395
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
 Appl.No PCT/US2025/021929 Applicant MODEL MEDICINES, INC. Inventor HADERS, Daniel
Disclosed herein are broad-spectrum antiviral compounds that can prevent or treat disorders related to RNA viral infections. Also disclosed are methods and composition for treating RNA viral infections, including symptoms of the RNA viral infections. The methods, for example, can include administering pharmaceutical compositions comprising one or more of the compounds disclosed herein to a patient in need.
3.20250296936SARS-COV2 MAIN PROTEASE INHIBITORS
US - 25.09.2025
Int.Class C07D 491/048
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
491Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/-C07D459/290
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
044with only one oxygen atom as ring hetero atom in the oxygen-containing ring
048the oxygen-containing ring being five-membered
 Appl.No 19045761 Applicant Gilead Sciences, Inc. Inventor Stephen E. Ammann

The present disclosure relates to compounds of Formula (I):

embedded image

and pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof, useful in the treatment of treating viral infections, for example, coronaviridae infections.

4.20250288561NEZULCITINIB FOR DELIVERY BY NEBULIZED ORAL INHALATION
US - 18.09.2025
Int.Class A61K 31/437
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
4353ortho- or peri-condensed with heterocyclic ring systems
437the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
 Appl.No 18862868 Applicant THERAVANCE BIOPHARMA R&D IP, LLC Inventor Nathan David PFEIFER

Provided herein is a method of treating a subject with a respiratory disorder when the subject is receiving high-flow oxygen through a nasal cannula, comprising administering a pharmaceutical composition comprising a therapeutic agent (such as nezulcitinib), or a pharmaceutically acceptable salt thereof, to the subject by oral nebulized inhalation.

5.20250276979SARS-COV2 MAIN PROTEASE INHIBITORS
US - 04.09.2025
Int.Class C07D 495/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
495Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
 Appl.No 19047099 Applicant Gilead Sciences, Inc. Inventor Stephen Ammann

The present disclosure relates to compounds of Formula I:

embedded image

and pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof, useful in the treatment of treating viral infections, for example, coronaviridae infections.

6.WO/2025/170972SARS-COV2 MAIN PROTEASE INHIBITORS
WO - 14.08.2025
Int.Class C07D 405/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
405Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
02containing two hetero rings
04directly linked by a ring-member-to-ring- member bond
 Appl.No PCT/US2025/014549 Applicant GILEAD SCIENCES, INC. Inventor AMMANN, Stephen E.
The present disclosure relates to compounds of Formula (I): and pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof, useful in the treatment of treating viral infections, for example, coronaviridae infections.
7.WO/2025/171130SARS-COV2 MAIN PROTEASE INHIBITORS
WO - 14.08.2025
Int.Class C07D 495/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
495Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
 Appl.No PCT/US2025/014787 Applicant GILEAD SCIENCES, INC. Inventor AMMANN, Stephen
The present disclosure relates to compounds of Formula I and pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof, useful in the treatment of treating viral infections, for example, coronaviridae infections.
8.12357577Pharmaceutical formulations and uses thereof
US - 15.07.2025
Int.Class A61K 9/20
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
9Medicinal preparations characterised by special physical form
20Pills, lozenges or tablets
 Appl.No 18431038 Applicant Gilead Sciences, Inc. Inventor Kimberly T. Barrett

Pharmaceutical formulations, particularly solid oral dosage forms (e.g., tablets) comprising (i) the compound of Formula I in an amount of about 40 wt % to about 70 wt %, (ii) a filler, (iii) a disintegrating agent, (iv) and a lubricant are disclosed, as are uses thereof.

9.20250205243SOLID FORMS OF A NUCLEOSIDE ANALOGUE AND USES THEREOF
US - 26.06.2025
Int.Class A61K 31/53
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
53having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
 Appl.No 18989013 Applicant Gilead Sciences, Inc. Inventor Stefani Kocevska

The disclosure provides solid forms of the compound of Formula (I) and uses thereof. Also provided are the methods of making the solid forms and pharmaceutical formulations comprising the solid forms.

10.WO/2025/137446SOLID FORMS OF A NUCLEOSIDE ANALOGUE AND USES THEREOF
WO - 26.06.2025
Int.Class C07H 19/23
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
19Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro derivatives thereof
02sharing nitrogen
04Heterocyclic radicals containing only nitrogen as ring hetero atom
23Heterocyclic radicals containing two or more heterocyclic rings condensed among themselves or condensed with a common carbocyclic ring system, not provided for in groups C07H19/14-C07H19/22222
 Appl.No PCT/US2024/061278 Applicant GILEAD SCIENCES, INC. Inventor KOCEVSKA, Stefani
The disclosure provides solid forms of the compound of Formula (I) and uses thereof. Also provided are the methods of making the solid forms and pharmaceutical formulations comprising the solid forms.
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