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CHEM:(ANQBLZWUYBPVED-UHFFFAOYSA-N)

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Analysis

1 / 1
1.2011178806NITROGENOUS FUSED HETEROAROMATIC RING DERIVATIVE
JP - 15.09.2011
Int.Class C07D 487/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
487Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/-C07D477/183
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
 Appl.No 2011106955 Applicant MSD KK Inventor TAKAHASHI TOSHIYUKI

PROBLEM TO BE SOLVED: To provide a compound which has a histamine-H3 receptor antagonistic effect or a histamine-H3 receptor inverse-agonistic effect and is useful for remedy of metabolic system diseases, circulatory system diseases or nervous system diseases.

SOLUTION: There is provided a compound or its pharmaceutically-acceptable salt of formula (I), [in the formula, A1 is hydrogen or the like; j and k each is 0 or 1, P and Q each forms a double bond or the like, with an adjacent carbon atom, one of W1 and W2 is E-O-W or the like, and the other is a hydrogen atom or the like, E is a divalent group derived from a benzene ring or the like, by removing two hydrogen atoms therefrom, and W is a specific aminoalkyl group or the like].

COPYRIGHT: (C)2011,JPO&INPIT

2.20070167453Nitrogenous fused heteroaromatic ring derivative
US - 19.07.2007
Int.Class C07D 487/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
487Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/-C07D477/183
 Appl.No 10589832 Applicant Banyu Pharmaceutical Co. Ltd. Inventor Takahashi Toshiyuki

The invention provides a compound or its pharmaceutically-acceptable salt of formula

embedded image
wherein A1 is a hydrogen, etc.; j and k are 0 or 1; custom character is a double bond, etc.; custom character is a double bond, etc.;
one of W1 and W2 is E—O—W, etc., and the other is a hydrogen atom, etc.; E is a divalent group derived from a benzene ring, etc., by removing two hydrogen atoms therefrom; W is a group of formula (II-1):

embedded image
which has a histamine-H3 receptor antagonistic effect or a histamine-H3 receptor inverse-agonistic effect and is useful for prevention or remedy of metabolic system diseases, circulatory system diseases or nervous system diseases.

3.1719756NITROGENOUS FUSED HETEROAROMATIC RING DERIVATIVE
EP - 08.11.2006
Int.Class C07D 487/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
487Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/-C07D477/183
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
 Appl.No 05710600 Applicant BANYU PHARMA CO LTD Inventor TAKAHASHI TOSHIYUKI
The invention provides a compound or its pharmaceutically-acceptable salt of formula (I): wherein A 1 is a hydrogen, etc.; j and k are 0 or 1; is a double bond, etc.; is a double bond, etc.; one of W 1 and W 2 is E-O-W, etc., and the other is a hydrogen atom, etc.; E is a divalent group derived from a benzene ring, etc., by removing two hydrogen atoms therefrom; W is a group of formula (II-1): which has a histamine-H3 receptor antagonistic effect or a histamine-H3 receptor inverse-agonistic effect and is useful for prevention or remedy of metabolic system diseases, circulatory system diseases or nervous system diseases.
4.WO2005077953含窒素縮合ヘテロ芳香環誘導体
JP - 25.08.2005
Int.Class C07D 487/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
487Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/-C07D477/183
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
 Appl.No 2005518077 Applicant ＭＳＤ株式会社 Inventor 高橋　敏行
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