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Analysis

1 / 9
1.2024204505Motion monitoring using projection imaging with rotating views
AU - 11.07.2024
Int.Class Appl.No 2024204505 Applicant Sydney Local Health District, Northern Inventor BOOTH, Jeremy
2.20240123259SYSTEM AND METHOD FOR DOSE GUIDANCE AND REPEATED ESTIMATION OF FINAL DELIVERED RADIATION DOSE FOR A RADIOTHERAPY SYSTEM
US - 18.04.2024
Int.Class A61N 5/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
5Radiation therapy
10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
 Appl.No 18272962 Applicant Ardos ApS Inventor Thomas Lyhne Ravkilde

A method for dose guidance for a radiotherapy system during a radiotherapy session includes the steps of: performing substantially real-time dose reconstruction to obtain a delivered radiation dose generated by a radiotherapy beam of the radiotherapy system in at least one volume; repeatedly estimating a remaining radiation dose based on an observed and/or simulated motion of the at least one volume; repeatedly estimating a final delivered radiation dose as a sum of the delivered radiation dose and the estimated remaining radiation dose; and providing dose guidance for a remaining part of the radiotherapy session based on the estimated final delivered radiation dose. A method of continuous estimation of final delivered radiation dose during a radiotherapy session and a decision support system for a radiotherapy system are also provided.

3.20230404504KALMAN FILTER FRAMEWORK TO ESTIMATE 3D INTRAFRACTION MOTION FROM 2D PROJECTION
US - 21.12.2023
Int.Class A61B 6/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
6Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
 Appl.No 18251341 Applicant SEETREAT PTY LTD Inventor Doan Trang NGUYEN

An iterative Kalman Filter method was developed to address the need for estimating randomly moving targets during cancer radiotherapy on a standard equipped linear accelerator. Extensive evaluation of this method using different treatment scenarios shows sub-mm accuracy and precision. In addition, the system and method allows the target (or surrogates of the target) to be monitored without the need of a learning arc, reducing additional imaging dose to the patient. In addition, the method and system performs robustly against imaging and segmentation noise.

4.WO/2023/235923MARKERLESS ANATOMICAL OBJECT TRACKING DURING AN IMAGE-GUIDED MEDICAL PROCEDURE
WO - 14.12.2023
Int.Class A61B 34/20
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
34Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
20Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
 Appl.No PCT/AU2023/050495 Applicant SEETREAT PTY LTD Inventor MYLONAS, Adam
An image guidance method for treatment by a medical device. The method comprises imaging a target area to which the treatment is to be delivered. During the interventional procedure, an image from the imaging is analysed by a patient-specific, individually trained artificial neural network to determine the position of at least one or more anatomical objects of interest present in the target area. The determined position(s) is output to the medical device for the delivery of treatment.
5.4284500SYSTEM AND METHOD FOR DOSE GUIDANCE AND REPEATED ESTIMATION OF FINAL DELIVERED RADIATION DOSE FOR A RADIOTHERAPY SYSTEM
EP - 06.12.2023
Int.Class A61N 5/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
5Radiation therapy
10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
 Appl.No 22702673 Applicant ARDOS APS Inventor MUURHOLM CASPER GAMMELMARK

The present disclosure relates to a method for dose guidance for a radiotherapy system during a radiotherapy session, comprising the steps of: performing substantially real-time dose reconstruction to obtain a delivered radiation dose generated by a radiotherapy beam of the radiotherapy system in at least one volume; repeatedly estimating a remaining radiation dose based on an observed and/or simulated motion of the at least one volume; repeatedly estimating a final delivered radiation dose as a sum of the delivered radiation dose and the estimated remaining radiation dose; and providing dose guidance for a remaining part of the radiotherapy session based on the estimated final delivered radiation dose. The present disclosure further relates to a method of continuous estimation of final delivered radiation dose during a radiotherapy session and a decision support system for a radiotherapy system.

6.WO/2023/215936METHOD AND SYSTEM FOR IMAGE REGISTRATION AND VOLUMETRIC IMAGING
WO - 16.11.2023
Int.Class G06T 7/33
GPHYSICS
06COMPUTING; CALCULATING OR COUNTING
TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
7Image analysis
30Determination of transform parameters for the alignment of images, i.e. image registration
33using feature-based methods
 Appl.No PCT/AU2023/050380 Applicant HINDLEY, Nicholas Inventor HINDLEY, Nicholas
The invention provides a system for image registration and volumetric imaging of a patient, the system comprising: a first interface adapted to receive 3D and/or 4D images of the patient; a second interface adapted to receive 2D images during a procedure carried out on the patient; and a processing unit wherein the processing unit is adapted to carry out a method comprising the steps of a method for image registration and volumetric imaging.
7.4240236A KALMAN FILTER FRAMEWORK TO ESTIMATE 3D INTRAFRACTION MOTION FROM 2D PROJECTION
EP - 13.09.2023
Int.Class A61B 5/11
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
103Measuring devices for testing the shape, pattern, size or movement of the body or parts thereof, for diagnostic purposes
11Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
 Appl.No 21888783 Applicant SEETREAT PTY LTD Inventor NGUYEN DOAN TRANG

An iterative Kalman Filter method was developed to address the need for estimating randomly moving targets during cancer radiotherapy on a standard equipped linear accelerator. Extensive evaluation of this method using different treatment scenarios shows sub-mm accuracy and precision. In addition, the system and method allows the target (or surrogates of the target) to be monitored without the need of a learning arc, reducing additional imaging dose to the patient. In addition, the method and system performs robustly against imaging and segmentation noise.

8.20230248442SYSTEM AND METHOD FOR CARDIAC STRUCTURE TRACKING
US - 10.08.2023
Int.Class A61B 34/20
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
34Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
20Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
 Appl.No 18014691 Applicant UNIVERSITY OF SYDNEY Inventor Nicholas HINDLEY

Systems, methods, and apparatus are disclosed for cardiac structure tracking. An example method includes segmenting a diaphragm or respiratory surrogate, heart, and target. The method also includes performing a peak-exhale to peak-inhale registration and generating a respiratory motion model. The method further includes tracking the diaphragm using X-ray imaging and estimating a target position for an x-ray guided cardiac radioablation treatment. The example method provides directly, precisely controlled x-ray guided cardiac radioablation that accurately targets the substrates of cardiac ablation while minimizing doses to healthy tissue.

9.WO/2023/115120DOSE-BASED OPTIMIZATION FOR MULTI-TARGET MULTI-LEAF COLLIMATOR ("MLC") TRACKING DURING RADIATION THERAPY METHODS AND APPARATUS
WO - 29.06.2023
Int.Class A61N 5/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
5Radiation therapy
10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
 Appl.No PCT/AU2022/051543 Applicant THE UNIVERSITY OF SYDNEY Inventor MEJNERTSEN, Lars
Methods, apparatuses and systems are disclosed for dose-based optimization related to multi-target multi-leaf collimator ("MLC") tracking during radiation therapy. In an example, a method includes calculating a planned radiation dose volume using an MLC plan and assigning dose voxels from the planned radiation dose volume to two or more patient tissue targets. The method also includes shifting the dose voxels such that the dose voxels that are assigned to one of the patient tissue targets are shifted according to motion of the respective patient tissue target, and integrating a delivered three-dimensional dose into a two-dimensional beam's eye view ("BEV") grid for each of the dose voxels. The method further includes fitting, for each leaf track, an MLC aperture by minimizing a cost function, accumulating a delivered dose based on the fitted leaf positions, and updating a gantry position and MLC leaf positions to update a next planned dose.
10.20230191152DOSE-BASED OPTIMIZATION FOR MULTI-LEAF COLLIMATOR ("MLC") TRACKING DURING RADIATION THERAPY METHODS AND APPARATUS
US - 22.06.2023
Int.Class A61N 5/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
5Radiation therapy
10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
 Appl.No 18014455 Applicant THE UNIVERSITY OF SYDNEY Inventor Lars MEJNERTSEN

Methods, apparatuses and systems are disclosed for dose-based optimization related to multi-leaf collimator (“MLC”) tracking during radiation therapy. In an example, a method includes calculating a planned radiation dose using an MLC plan in an unshifted dose volume, acquiring, using a radiation machine, a target position through motion tracking, and shifting the dose volume by the target position. The method also includes integrating a three-dimensional dose into a two-dimensional beam’s eye view grid and fitting, using the radiation machine for each leaf track, an MLC aperture by minimizing a cost function. The method further includes calculating and accumulating a delivered dose based on the fitted leaf positions of the MLC and updating a gantry position and MLC leaves to update a next planned dose.

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