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IC:C07D

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Analysis

1.20210127725AN ISOMALTULOSE BASED SWEETENER
US 06.05.2021
Int.Class A23L 27/30
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D91; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
27Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
30Artificial sweetening agents
Appl.No 16635820 Applicant Evonik Operations GmbH Inventor Thomas HAAS

The present invention relates to a sweetener comprising

20 wt. % to 75 wt. % of α-D-glucopyranosyl-1,6-D-sorbitol,

20 wt. % to 75 wt. % of α-D-glucopyranosyl-1,1-D-mannitol,

0.02 wt. % to 15 wt. % of α-D-glucopyranosyl-1,1-D-sorbitol,

0.02 wt. % to 15 wt. % of sorbitol

0.02 wt. % to 15 wt. % of mannitol,

less than 0.3 wt. % of sucrose, and

less than 0.0002 wt. % furan and derivatives thereof in each case relative to the total weight of dry matter of the sweetener and a method of producing the same.

2.20210128532HETEROCYCLIC CARBOXYLATE COMPOUNDS AS GLYCOLATE OXIDASE INHIBITORS
US 06.05.2021
Int.Class A61K 31/4192
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
41having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
41921,2,3-Triazoles
Appl.No 17081940 Applicant GyanRx Sciences, Inc. Inventor Julian A. Codelli

The present disclosure relates generally to modulators of human glycolate oxidase enzyme and methods of use and manufacture thereof.

3.20210128578CHARGED ION CHANNEL BLOCKERS AND METHODS FOR USE
US 06.05.2021
Int.Class A61K 31/55
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
55having seven-membered rings, e.g. azelastine, pentylenetetrazole
Appl.No 17098678 Applicant Nocion Therapeutics, Inc. Inventor Bridget McCarthy Cole

The invention provides compounds of Formula (I), or pharmaceutically acceptable salts thereof:

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The compounds, compositions, methods and kits of the invention are useful for the treatment of pain, itch, and neurogenic inflammation.

4.WO/2021/083879BROMODOMAIN INHIBITORS
WO 06.05.2021
Int.Class A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
Appl.No PCT/EP2020/080156 Applicant RHEINISCH-WESTFÄLISCHE TECHNISCHE HOCHSCHULE (RWTH) AACHEN Inventor BOLM, Carsten
The invention relates to compounds according to the general formula (1), to their use for producing a medicament, in particular for the treatment of bromodomain-related diseases, such as cancers.
5.WO/2021/0853192,6-NAPHTHALENEDIOL-BIS(TRIMELLITATE ANHYDRIDE) POWDER AND METHOD FOR PRODUCING SAME
WO 06.05.2021
Int.Class C07B 61/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
61Other general methods
Appl.No PCT/JP2020/039834 Applicant HONSHU CHEMICAL INDUSTRY CO., LTD. Inventor KANO, Ryoto
This invention addresses the problem of providing: a 2,6-naphthalenediol-bis(trimellitate anhydride) powder that is easy to handle; and a method for producing the same. This invention solves the problem by providing: a 2,6-naphthalenediol-bis(trimellitate anhydride) powder characterized by having a median diameter within a range from 10 to 100 µm; and a method for producing the same.
6.WO/2021/086069COMPOUND COMPRISING EZH2 INHIBITOR AND E3 LIGASE BINDER AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING EZH2-ASSOCIATED DISEASE COMPRISING SAME AS ACTIVE INGREDIENT
WO 06.05.2021
Int.Class C07D 405/14
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
405Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
14containing three or more hetero rings
Appl.No PCT/KR2020/014936 Applicant DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION Inventor YU, Ji-Hoon
The present invention relates to a compound comprising an EZH2 inhibitor and an E3 ligase binder, and a pharmaceutical composition for preventing or treating EZH2-associated disease and a pharmaceutical composition for selectively degrading protein, each containing the compound as an active ingredient. The compound is capable of selectively degrading EZH2, and thus can be usefully applied for treatment of EZH2-associated disease or cancer, specifically a cancer in which EZH2 is overexpressed.
7.WO/2021/086099ANTHRACENE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME
WO 06.05.2021
Int.Class C07D 307/91
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
307Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
77ortho- or peri-condensed with carbocyclic rings or ring systems
91Dibenzofurans; Hydrogenated dibenzofurans
Appl.No PCT/KR2020/015006 Applicant LG CHEM, LTD. Inventor KIM, Hoon Jun
The present specification relates to an anthracene compound represented by chemical formula 1 and an organic light-emitting device comprising same.
8.WO/2021/086234NOVEL CHEMICAL COMPOUND L-LYSINE 9-OXOACRIDINYL-10-ACETATE
WO 06.05.2021
Int.Class C07D 219/06
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
219Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
04with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
06Oxygen atoms
Appl.No PCT/RU2020/050289 Applicant SCIENTIFIC TECHNOLOGICAL PHARMACEUTICAL FIRM "POLYSAN" LTD. Inventor KOVALENKO, Alexey Leonidovich
The invention relates to chemistry, pharmaceuticals and medicine, and specifically to a new chemical compound of the class of derivatives of 9-oxoacridinyl-10-acetate: L-lysine 9-oxoacridinyl-10-acetate, which stimulates production of interleukin-24 (IL-24) and tumor necrosis factor beta (TNF-β) and has anti-tumor activity. The invention may be used in anti-tumor therapy, in particular, as an adjuvant in the complex treatment of oncological diseases. The invention addresses the problem of creating a novel chemical compound which stimulates production of the cytokines interleukin-24 and tumor necrosis factor beta and exhibits anti-tumor activity with low toxicity. The stated problem is solved by a novel chemical compound: L-lysine 9-oxoacridinyl-10-acetate of formula (I) or (II).
9.WO/2021/087299SOLID FORMS OF AN S1P-RECEPTOR MODULATOR
WO 06.05.2021
Int.Class C07D 498/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
498Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
Appl.No PCT/US2020/058269 Applicant E-SCAPE BIO, INC. Inventor DE LOMBAERT, Stéphane
This application relates to solid forms of an SIP-receptor modulator of the formula below, which are useful in the treatment of diseases or disorders associated with activity of SIP, including CNS disorders. Compound 1.
10.WO/2021/085635REACTION AGENT FOR AMIDE REACTION AND METHOD FOR PRODUCING AMIDE COMPOUND USING SAME
WO 06.05.2021
Int.Class C07C 231/22
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
231Preparation of carboxylic acid amides
22Separation; Purification; Stabilisation; Use of additives
Appl.No PCT/JP2020/040951 Applicant CHUBU UNIVERSITY EDUCATIONAL FOUNDATION Inventor YAMAMOTO, Hisashi
The present invention provides a novel means capable of producing an amide compound by highly stereoselectively and/or highly efficiently causing an amide reaction in various substrates having a carboxyl group and an amino group. This reaction agent causes an amide reaction between a carboxyl group and an amino group, and contains a silane compound represented by general formula (C1) or the like. (In general formula (C1), each substituent is as defined in the claims)