Processing

Please wait...

Settings

Settings

Goto Application

Offices all Languages Stemming false Single Family Member true Include NPL false

Save query

A private query is only visible to you when you are logged-in and can not be used in RSS feeds

Query Tree

Refine Options

Offices
All
Specify the language of your search keywords
Stemming reduces inflected words to their stem or root form.
For example the words fishing, fished,fish, and fisher are reduced to the root word,fish,
so a search for fisher returns all the different variations
Returns only one member of a family of patents
Include Non-Patent literature in results

Full Query

IC:C12P19/34

Side-by-side view shortcuts

General
Go to Search input
CTRL + SHIFT +
Go to Results (selected record)
CTRL + SHIFT +
Go to Detail (selected tab)
CTRL + SHIFT +
Go to Next page
CTRL +
Go to Previous page
CTRL +
Results (First, do 'Go to Results')
Go to Next record / image
/
Go to Previous record / image
/
Scroll Up
Page Up
Scroll Down
Page Down
Scroll to Top
CTRL + Home
Scroll to Bottom
CTRL + End
Detail (First, do 'Go to Detail')
Go to Next tab
Go to Previous tab

Analysis

1.20210130799PRODUCTION OF CYCLIC ADENYLATES AND THEIR USE AS ALLOSTERIC REGULATORS
US 06.05.2021
Int.Class C12N 9/22
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
14Hydrolases (3.)
16acting on ester bonds (3.1)
22Ribonucleases
Appl.No 16618238 Applicant VILNIUS UNIVERSITY Inventor Virginijus SIKSNYS

A method of synthetizing cyclic oligoadenylates using a novel catalytic activity of a protein possessing the Palm domain, such as the Cas10 protein, and using such compounds for activation of proteins possessing the CARF doman, such as the Csm6 protein.

2.WO/2021/081472SYSTEMS AND METHODS FOR MEASURING COLORIMETRIC REACTIONS
WO 29.04.2021
Int.Class B01L 3/00
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
3Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
Appl.No PCT/US2020/057261 Applicant FABRICO TECHNOLOGY INC Inventor KASKIN, Alex
A system includes a cartridge and an instrument. The cartridge includes a cartridge body defining an input port aligned with a central axis of the cartridge body, a plurality of channels in fluidic communication with the input port and extending radially to a plurality of reaction chamber connectors, a plurality of reaction chambers disposed at a radial distance from the central axis of the cartridge body and distributed at angles relative to the others of the plurality of reaction chambers. The system further includes an instrument including an incubation block configured to receive the plurality of reaction chambers; a motor and socket to connect with the cartridge; an illumination source having an illumination pathway; and a camera disposed in a signal pathway intersecting the illumination pathway.
3.20210123096COMPOSITIONS AND METHODS FOR NUCLEIC ACID AMPLIFICATION
US 29.04.2021
Int.Class C12Q 1/6853
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
6844Nucleic acid amplification reactions
6853using modified primers or templates
Appl.No 17139127 Applicant AMPLIWISE INC. Inventor Kai Wu

An embodiment relates to system comprising: (i) a reaction mixture comprises: a) a target nucleic acid molecule; b) a forward primer complementary to a strand of the target nucleic acid molecule, the forward primer comprises a first molecular moiety at a 3′ end, wherein the first molecular moiety is non-complementary to the strand of the target nucleic acid molecule; c) a reverse primer complementary to a complementary sequence of the strand of the target nucleic acid molecule, the reverse primer comprises a second molecular moiety at a 3′ end, wherein the second molecular moiety is non-complementary to the complementary sequence of the strand of the target nucleic acid molecule; d) a polymerase with 3′-5′ exonuclease activity; and (ii a device suitable of detecting an amplification products.

4.WO/2021/076423DETECTION OF SEQUENCES UNIQUELY ASSOCIATED WITH A DNA TARGET REGION
WO 22.04.2021
Int.Class C12Q 1/68
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
Appl.No PCT/US2020/055079 Applicant PIONEER HI-BRED INTERNATIONAL, INC. Inventor ACHARYA, Ananta
The disclosed embodiments concern methods for determining sequences of interest using targeted unique molecular index (TUMI) sequences that are uniquely associated with individual polynucleotide fragments in plants, such as those present in a transgenic event, a site-specific mutation or a wild type variant. System, apparatus, and computer program products are also provided for determining a sequence of interest implementing the methods disclosed.
5.20210115437IN VITRO SYNTHESIS METHOD FOR SGRNA AND KIT THEREOF
US 22.04.2021
Int.Class C12N 15/11
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
11DNA or RNA fragments; Modified forms thereof
Appl.No 17043119 Applicant SHANGHAI SINOBIO BIOTECH CO. LTD. Inventor Huaxing ZHU

The present invention provides an in vitro synthesis method for an sgRNA and a kit thereof. Specifically, the present invention provides a nucleic acid construct having a structure represented by formula I from 5′ to 3′: Y1-L1-Y2-L2-Y3-Y4 (I), wherein Y1 is an RNA polymerase promoter region; L1 is absent or a linking sequence; Y2 is a target DNA sequence; L2 is absent or a linking sequence; Y3 is a downstream primer binding region; Y4 is absent or a nucleotide sequence; and each “-” is independently a bond or a nucleotide linking sequence.

6.WO/2021/073627USING PROTEASES TO CONTROL RESTRICTION ENZYME ACTIVITY
WO 22.04.2021
Int.Class C12N 9/22
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
14Hydrolases (3.)
16acting on ester bonds (3.1)
22Ribonucleases
Appl.No PCT/CN2020/121723 Applicant ABCLONAL BIOTECHNOLOGY CO., LTD Inventor ZHU, Zhenyu
Provided is a method of using proteases including proteinase K, endoproteinase LysC and/or trypsin to control the activity of restriction enzymes and/or eliminate or reduce production of unwanted DNA or RNA fragments.
7.WO/2021/075293MRNA AND METHOD FOR PRODUCING SAME, AND APPARATUS FOR PRODUCING PROTEIN AND METHOD FOR PRODUCING PROTEIN
WO 22.04.2021
Int.Class C12N 15/11
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
11DNA or RNA fragments; Modified forms thereof
Appl.No PCT/JP2020/037706 Applicant JAPAN SCIENCE AND TECHNOLOGY AGENCY Inventor ABE Hiroshi
Provided is a mRNA that is used for protein synthesis, and contains a translated region having a start codon and a stop codon and an untranslated region located on the 5'-terminal side of the start codon, wherein some of phosphate groups in at least the range from the 5'-terminal of the untranslated region to 15 nts on the 3'-terminal side of the start codon have replaced with phosphorothioate groups. This method for producing mRNA comprises a step for preparing a DNA template; a step for preparing unmodified NTPs comprising ATP, GTP, CTP, and UTP and preparing modified NTPs in which phosphate groups of at least one kind of these unmodified NTPs are replaced with the phosphorothioate group; and a step for carrying out a transcription reaction using RNA polymerase and using the DNA template as the template and the unmodified NTPs and modified NTPs as substrates.
8.112661861重组聚合酶、编码基因、制备方法、载体、试剂盒及应用
CN 16.04.2021
Int.Class C07K 19/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
19Hybrid peptides
Appl.No 202011560453.1 Applicant 湖北大学 Inventor 王亚平
本发明属于分子生物学和蛋白质工程技术领域,公开了一种重组聚合酶、编码基因、制备方法、载体、试剂盒及应用,重组聚合酶来源于Thermus aquaticus YT‑1菌株中的Taq DNA聚合酶蛋白序列N端以柔性连接序列共价连接蛋白Cl7而得到的杂合DNA聚合酶,氨基酸序列如SEQ ID No.4所示,或该序列经替换、缺失或添加一个或几个氨基酸形成的具有同等功能的氨基酸序。本发明表达载体pET30a‑Cl7‑Taq转化大肠杆菌、诱导表达得到目的蛋白Cl7‑Taq。本发明大大提高TaqDNA聚合酶在PCR核酸扩增的持续合成能力,具有广泛的应用前景。
9.WO/2021/070616TRANSLATION PROMOTER, TEMPLATE NUCLEIC ACID, METHOD FOR PRODUCING TRANSLATION TEMPLATE, AND METHOD FOR PRODUCING PROTEIN
WO 15.04.2021
Int.Class C12P 19/34
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
19Preparation of compounds containing saccharide radicals
26Preparation of nitrogen-containing carbohydrates
28N-glycosides
30Nucleotides
34Polynucleotides, e.g. nucleic acids, oligoribonucleotides
Appl.No PCT/JP2020/035949 Applicant NUPROTEIN CO., LTD. Inventor TADA Hiroaki
The present invention addresses the problem of providing a translation promoter which improves the synthesis efficiency of a target protein. This problem can be solved by a translation promoter in a cell-free protein synthesis system, the translation promoter comprising a nucleic acid which is a 3'-untranslated region linked adjacent to the 3'-end of a coding region encoding the amino acid sequence of a target protein, wherein: the 3'-untranslated region is configured of a first region, which is adjacent to the 3'-end of the coding region and comprises a nucleic acid sequence consisting of 10 to 40 bases, and a second region which comprises a poly A sequence consisting of consecutive 2 to 40 A's linked to the first region; and the first region has a hairpin structure.
10.WO/2021/072035COMPOSITIONS, METHODS AND KITS FOR BIOLOGICAL SAMPLE AND RNA STABILIZATION
WO 15.04.2021
Int.Class C12N 15/10
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
10Processes for the isolation, preparation or purification of DNA or RNA
Appl.No PCT/US2020/054719 Applicant LIQUID BIOPSY RESEARCH LLC Inventor MODLIN, Irvin Mark
The present disclosure provides a buffer comprising at least one chaotropic agent, at least one chelating agent and at least one non-ionic surfactant, wherein the buffer stabilizes a biological sample at about room temperature for at least about one day.