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IC:A61B5/08 AND EN_ALLTXT:(coronavirus OR coronaviruses OR coronaviridae OR coronavirinae OR orthocoronavirus OR orthocoronaviruses OR orthocoronaviridae OR orthocoronavirinae OR betacoronavirus OR betacoronaviruses OR betacoronaviridae OR betacoronavirinae OR sarbecovirus OR sarbecoviruses OR sarbecoviridae OR sarbecovirinae OR "severe acute respiratory syndrome" OR sars OR "2019 ncov" OR covid)

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Analysis

1 / 80
1.20250107725REAL-TIME BREATH ANTIGEN DETECTION SYSTEM AND METHOD THEREOF
US - 03.04.2025
Int.Class A61B 5/08
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes ; Identification of persons
08Measuring devices for evaluating the respiratory organs
 Appl.No 18833034 Applicant Charité – Universitätmedizin Berlin Inventor Tim Bierewirtz

A system for antigen detection is provided that includes a first container configured to collect aerosols out of exhaled air of a human and a second container suitable for a solvent, wherein nanoparticles are dissolved in the solvent and the nanoparticles are linked to antibodies. A change of optical properties of the solvent is detectable upon contact between the antibodies and matching antigens. Aerosols exhaled in the air stick in a filter on one side of the first container. Thereupon, the first container is incooperable in the second container, in which a solvent with nanoparticles dissolved therein and antibodies coupled thereto are located. If antigens matching the antibodies are present on the aerosols, the nanoparticles agglomerate around the antigen, changing the optical properties of the solvent, which is irradiated by a light source and detectable by a light sensor.

2.WO/2023/144291REAL-TIME BREATH ANTIGEN DETECTION SYSTEM AND METHOD THEREOF
WO - 03.08.2023
Int.Class A61B 5/08
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes ; Identification of persons
08Measuring devices for evaluating the respiratory organs
 Appl.No PCT/EP2023/051983 Applicant CHARITÉ - UNIVERSITÄTSMEDIZIN BERLIN Inventor BIEREWIRTZ, Tim
The invention relates to a system for antigen detection comprising a first container configured to collect aerosols out of exhaled air of a human and a second container suitable for a solvent, wherein nanoparticles are dissolved in the solvent and the nanoparticles are linked to antibodies, further wherein a change of optical properties of the solvent is detectable upon contact between the antibodies and matching antigens. Here, a person can exhale air into the first container, and the aerosols exhaled in the air stick in a filter on one side of the first container. Thereupon, the first container is incooperable in the second container, in which a solvent with nanoparticles dissolved therein and antibodies coupled thereto are located. The incooperability, in particular a shuttling stroke motion, flushes the aerosols into the solvent. If antigens matching the antibodies are present on the aerosols, the nanoparticles agglomerate around the antigen, changing the optical properties of the solvent, which is irradiated by a light source and detectable by a light sensor. In further aspects, the invention relates to a method using the system according to the invention. The invention further relates to corresponding medical uses and therapeutic methods of administering a prevention of a medical condition associated with a SARS Coronavirus, in addition to diagnostic uses and methods.
3.2023213096REAL-TIME BREATH ANTIGEN DETECTION SYSTEM AND METHOD THEREOF
AU - 25.07.2024
Int.Class A61B 5/08
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes ; Identification of persons
08Measuring devices for evaluating the respiratory organs
 Appl.No 2023213096 Applicant CHARITÉ - UNIVERSITÄTSMEDIZIN BERLIN Inventor BIEREWIRTZ, Tim
4.4218562REAL-TIME BREATH ANTIGEN DETECTION SYSTEM AND METHOD THEREOF
EP - 02.08.2023
Int.Class A61B 5/08
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes ; Identification of persons
08Measuring devices for evaluating the respiratory organs
 Appl.No 22153898 Applicant UNIV BERLIN CHARITE Inventor BIEREWIRTZ TIM
The invention relates to a system for antigen detection comprising a first container configured to collect aerosols out of exhaled air of a human and a second container suitable for a solvent, wherein nanoparticles are dissolved in the solvent and the nanoparticles are linked to antibodies, further wherein a change of optical properties of the solvent is detectable upon contact between the antibodies and matching antigens. Here, a person can exhale air into the first container, and the aerosols exhaled in the air stick in a filter on one side of the first container. Thereupon, the first container is incooperable in the second container, in which a solvent with nanoparticles dissolved therein and antibodies coupled thereto are located. The incooperability, in particular a shuttling stroke motion, flushes the aerosols into the solvent. If antigens matching the antibodies are present on the aerosols, the nanoparticles agglomerate around the antigen, changing the optical properties of the solvent, which is irradiated by a light source and detectable by a light sensor.In further aspects, the invention relates to a method using the system according to the invention.The invention further relates to corresponding medical uses and therapeutic methods of administering a prevention of a medical condition associated with a SARS Coronavirus, in addition to diagnostic uses and methods.
5.20240277252MULTIPLEXED ANTIGEN-BASED DETECTION OF SARS-COV-2 AND OTHER DISEASES USING NANOMECHANICAL SENSORS
US - 22.08.2024
Int.Class A61B 5/08
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes ; Identification of persons
08Measuring devices for evaluating the respiratory organs
 Appl.No 18572345 Applicant Northwestern University Inventor Vinayak P. Dravid

Nanomechanical sensors comprising an antibody-functionalized microcantilever and methods of using the same are described herein.

6.2023243036RAPID, SINGLE-USE METHODS AND SYSTEMS FOR ELECTROCHEMICAL ANALYSIS OF PATHOGENS IN EXHALED BREATH
AU - 05.10.2023
Int.Class A61B 5/08
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes ; Identification of persons
08Measuring devices for evaluating the respiratory organs
 Appl.No 2023243036 Applicant WASHINGTON UNIVERSITY Inventor CHAKRABARTY, Rajan
7.WO/2022/013877METHOD AND SYSTEM FOR PREPARING A SAMPLE FOR DETECTION OF PROTEINS
WO - 20.01.2022
Int.Class A61B 5/08
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes ; Identification of persons
08Measuring devices for evaluating the respiratory organs
 Appl.No PCT/IL2021/050869 Applicant BREATH OF HEALTH LTD. Inventor LAOR, Marsel Arie
The present invention provides a system including a pump configured to pump an air sample, from a container to a cooling chamber, at a capacity of at least 0.5 liter/sec, the cooling chamber is configured to cool the exhaled air sample to a sub-zero temperature, and is in fluid connection to a spectrometer test chamber; an inert gas source, configured to supply an inert gas to the test chamber at a pressure higher than the atmospheric pressure; and a heating unit for heating said air sample. Further provided is a method for preparing an air sample for detection of a mixture of proteins.
8.20250172523RAPID, SINGLE-USE METHODS AND SYSTEMS FOR ELECTROCHEMICAL ANALYSIS OF PATHOGENS IN EXHALED BREATH
US - 29.05.2025
Int.Class G01N 27/327
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
27Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
26by investigating electrochemical variables; by using electrolysis or electrophoresis
28Electrolytic cell components
30Electrodes, e.g. test electrodes; Half-cells
327Biochemical electrodes
 Appl.No 18851157 Applicant Washington University Inventor Benjamin Sumlin

The present disclosure is directed to an exhaled breath condensate (EBC) collection device for collecting pathogens for analysis, the device comprising including: a breathing tube; and a condensing chamber located downstream from and in flow communication with the breathing tube, wherein where the condensing chamber includes an upper chamber and a lower chamber separated by a superhydrophobic surface.

9.WO/2024/116103METHOD AND SYSTEM FOR DETECTING NON-VOLATILE AND SEMI-VOLATILE ORGANIC COMPOUNDS IN MID-IR SPECTROMETRY GAS CELL CONFIGURATIONS
WO - 06.06.2024
Int.Class G01N 1/38
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
1Sampling; Preparing specimens for investigation
28Preparing specimens for investigation
38Diluting, dispersing or mixing samples
 Appl.No PCT/IB2023/062047 Applicant BREATH OF HEALTH LTD. Inventor LAOR, Marsel Arie
The embodiments provide a system including a pump configured to pump an air sample, from a container to a cooling chamber, the cooling chamber configured to cool the exhaled air sample to a sub-zero temperature, and is in fluid communication with an injector unit. The injector unit mixes the cooled air sample and inert gas and injects the mixed air sample at a high velocity to a test chamber. Further provided is a method for preparing an air sample for detection of a mixture of proteins.
10.WO/2023/192433RAPID, SINGLE-USE METHODS AND SYSTEMS FOR ELECTROCHEMICAL ANALYSIS OF PATHOGENS IN EXHALED BREATH
WO - 05.10.2023
Int.Class A61B 5/08
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes ; Identification of persons
08Measuring devices for evaluating the respiratory organs
 Appl.No PCT/US2023/016822 Applicant WASHINGTON UNIVERSITY Inventor SUMLIN, Benjamin
The present disclosure is directed to an exhaled breath condensate (EBC) collection device for collecting pathogens for analysis, the device comprising: a breathing tube; and a condensing chamber located downstream from and in flow communication with the breathing tube, wherein the condensing chamber includes an upper chamber and a lower chamber separated by a superhydrophobic surface.
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