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Analysis

1.WO/2022/109537APPARATUS AND METHODS FOR MOLECULAR DIAGNOSTICS
WO 27.05.2022
Int.Class C12M 1/34
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
34Measuring or testing with condition measuring or sensing means, e.g. colony counters
Appl.No PCT/US2021/072418 Applicant NUCLEIN, LLC Inventor CROCKETT, Richard
This disclosure relates to apparatus and methods for molecular diagnostics. Certain embodiments include a piston cycled from a first position proximal to a first end of a housing, to a second position proximal to a second end of the housing, and back to the first position proximal to the first end of the housing. In some embodiments, the present disclosure relates to devices, methods, and systems for molecular diagnostics that do not comprise a piston.
2.WO/2022/109612CENTRIFUGAL SEPARATORS AND SKID FOR SEPARATING BIOCOMPONENTS AND METHODS OF USE
WO 27.05.2022
Int.Class B04B 7/02
BPERFORMING OPERATIONS; TRANSPORTING
04CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
BCENTRIFUGES
7Elements of centrifuges
02Casings; Lids
Appl.No PCT/US2021/072534 Applicant LIFE TECHNOLOGIES CORPORATION Inventor SMITH, Mark T.
A skid (700) for use in separating biocomponents includes a housing (701) bounding a compartment (708), the compartment being partially bounding by a mounting platform (709); and a loading assembly (800) secured to the housing so as to communicate with the compartment. The loading assembly (800) includes an alignment plate (808) having a top surface with cavity (814) recessed therein, the cavity communicating with the compartment; a drive rotor (15) rotatably disposed below the alignment plate and at least partially encircling the cavity, the drive rotor including one or more magnets; a motor (169) coupled to the drive rotor for selectively rotating the drive rotor about the cavity; and a mount at least partially encircling the drive rotor and communicating with the compartment, the mount including a mounting plate having one or more mounting elements upstanding therefrom, the mount being movable between a raised position wherein the mounting plate is aligned with the alignment plate and a second lowered position wherein the mounting plate is disposed at an elevation lower than the alignment plate.
3.WO/2022/109371FILTRATION SYSTEMS,COMPONENTS AND METHODS
WO 27.05.2022
Int.Class B01D 61/14
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
DSEPARATION
61Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
14Ultrafiltration; Microfiltration
Appl.No PCT/US2021/060264 Applicant ABEC, INC. Inventor KLOPP, Chris
This disclosure generally relates to purification systems using tangential flow filtration ("TFF") ("TFF systems") that include at least one single-use, disposable flow path wherein the disposable flow path is comprised of a disposable cassette manifold, disposable tubing (including associated components) and a disposable reactor vessel.
4.WO/2022/107067CUVETTE FOR MACROSCALE 3D GROWTH AND TREATMENT OF CELLS
WO 27.05.2022
Int.Class C12M 3/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
3Tissue, human, animal or plant cell, or virus culture apparatus
Appl.No PCT/IB2021/060753 Applicant REAL RESEARCH SP. Z O. O. Inventor KRZYKAWSKI, Marcin
The subject of the invention is a cuvette (3) for 3D cell culture growth comprising a main container (5) comprising a means for macroscale 3D growth of cells and two end covers (4) at inlet and outlet ends of the main container (5), connected with cell culture media input and output tubing, wherein fluid transportation ports (7) placed at the inlet and outlet end covers (4), wherein the cuvette is preferably transparent and filled with transparent hydrogel.
5.WO/2022/108117CEREBRAL ORGANOID-MOTOR NEURON SPHEROID STRUCTURE AND FABRICATION METHOD THEREFOR
WO 27.05.2022
Int.Class C12N 5/0793
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
07Animal cells or tissues
071Vertebrate cells or tissues, e.g. human cells or tissues
079Neural cells
0793Neurons
Appl.No PCT/KR2021/014097 Applicant SOGANG UNIVERSITY RESEARCH & BUSINESS DEVELOPMENT FOUNDATION Inventor CHOI, Jeong-Woo
The present invention relates to a cerebral organoid-motor neuron spheroid structure and a fabrication method therefor. The structure can be fabricated by co-culturing a cerebral organoid and motor neuron spheroids in a co-culture chip which is designed to bring the cerebral organoid and the motor neuron spheroids into independent contact with a proper culture medium. The structure can be effectively used for screening drugs for prevention or treatment of brain diseases causative of motor disturbance or for a toxicity assay because electrical signal change of motor neurons according to specific substances stimulating the cerebrum can be observed from the structure.
6.WO/2022/107006METHODS AND DEVICES FOR RAPID DETECTION OF COVID-19 AND OTHER PATHOGENS
WO 27.05.2022
Int.Class C12Q 1/6844
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
6844Nucleic acid amplification reactions
Appl.No PCT/IB2021/060631 Applicant KHALIFA UNIVERSITY OF SCIENCE AND TECHNOLOGY Inventor ALAZZAM, Anas
A device (10) and method for detecting COVID-19 and other pathogens includes a sample compartment (26) contained within an interior of the device and having multiple apertures (32) for releasably receiving one or more test tubes (42) containing a biological sample. A bottom portion (48) of the test tube (42) is contained within the interior (22) of the device (10) and a top portion (46) of the test tube (42) is exposed to atmosphere. The biological sample is lysed using the device (10); the lysed sample is mixed with one or more primers and then amplification (RT-LAMP) is performed using the device (10). A thermally conductive material on or in proximity to the sample compartment (26) can facilitate precise heating of the compartment (26) and sample. A thermally insulative material can be inside the interior of the compartment housing (30). Multiple samples can be tested simultaneously. The results can be interpreted by a color change of the sample. The device (10) is efficient, portable, reliable, and re-usable.
7.WO/2022/106480APPARATUS FOR BIO-PRODUCT PROCESSING
WO 27.05.2022
Int.Class B01D 15/22
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
DSEPARATION
15Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
08Selective adsorption, e.g. chromatography
10characterised by constructional or operational features
22relating to the construction of the column
Appl.No PCT/EP2021/082008 Applicant CYTIVA SWEDEN AB Inventor ERIKSSON, Stefan, K
The present invention relates to an apparatus (200) for bio-product processing. The apparatus (200) comprise a processing column (201) comprising an upper column tube (202B) releasably coupled to a lower column tube (202A). The lower column tube (202A) has a processing chamber (218) provided therein. The apparatus (200) additionally comprises an adapter (222) for moving within the processing column (201) so as to vary the volume of the processing chamber (218) within the lower column tube (202A), and a column stand (214) for supporting the adapter (222).
8.WO/2022/106165SYSTEM AND METHOD FOR ASEPTIC SAMPLING AND FLUID ADDITION
WO 27.05.2022
Int.Class C12M 1/26
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
26Inoculator or sampler
Appl.No PCT/EP2021/079802 Applicant GLOBAL LIFE SCIENCES SOLUTIONS USA LLC Inventor TIMMINS, Mark, R
A sampling system includes a graduated sampling chamber configured for fluid connection to a sample source, a pump device configured for fluid connection with the sampling chamber, and a sterile air filter intermediate the pump device and the sampling chamber, wherein the pump device is selectively actuatable to draw a volume of fluid from the sample source into the sampling chamber.
9.WO/2022/107604PROCESSING DEVICE, NUCLEIC ACID EXTRACTION SYSTEM, AND NUCLEIC ACID ANALYSIS SYSTEM
WO 27.05.2022
Int.Class C12M 1/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
Appl.No PCT/JP2021/040563 Applicant YOKOGAWA ELECTRIC CORPORATION Inventor KUWATA Masahiro
In the present invention, a container 30 has a plurality of accommodation portions (310) for accommodating samples and a lid (320) for closing the plurality of accommodation portions (310). A processing device (6) has: a container support portion (41) that supports the plurality of accommodation portions (310); and a container fixing portion (42) that overlaps the lid (320), sandwiches the container (30) together with the container support portion (41), and is provided so as to be capable of opening and closing with respect to the container support portion (41). A plurality of holes (411) are provided in the container support portion (41), and a plurality of hook portions (420) that are inserted into the plurality of holes (411) and engage with edges (411a) of the plurality of holes (411) are provided to the container fixing portion (42).
10.WO/2022/104708DEPTH-ADJUSTABLE MARINE LIFE MEASURING AND COLLECTING APPARATUS
WO 27.05.2022
Int.Class C12M 1/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
Appl.No PCT/CN2020/130455 Applicant TANGSHAN HARBIN SHIP TECHNOLOGY CO., LTD. Inventor WANG, Xiaoxi
A depth-adjustable marine life measuring and collecting apparatus, comprising a base (1), a column (2) fixedly mounted on the top part of the base (1), a first through hole provided on the column (2), a first rotatable rod (4) rotatably mounted in the first through hole, an electric motor (3) fixedly mounted at one side of the column (2), an output shaft of the electric motor (3) being fixedly connected to one end of the first rotatable rod (4), a roller (5) fixedly mounted at the other end of the first rotatable rod (4), and a steel cable (6) reeled on the roller (5). The marine life measuring and collecting apparatus, during a process collecting marine life samples, adjusts the depth at which measurements and collections are done, prevents a filter plate from being blocked during the collecting process, increases the amount collected, is structurally simple, and is convenient to use.