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Analysis

1.20230037035BIOCHEMICAL DETECTION DEVICE
US 02.02.2023
Int.Class B01L 3/00
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
3Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
Appl.No 17443549 Applicant TAIWAN SWABS TECHNOLOGY COMPANY Inventor CHIH-PING WEI

A biochemical detection device is revealed. The biochemical detection device includes a cap and a base arranged at two ends of a test tube correspondingly and a driving member disposed on the base. A sample-mounting slot and a test-paper-mounting slot separated from each other are formed in the test tube. After sampling, a sample obtained is placed into the sample-mounting slot and mixed with an extraction solution therein. A thin-film on the sample-mounting slot is penetrated by the driving member to allow the extraction solution mixed with the sample flowing into a cavity of the test tube to react with a test strip in the test-paper-mounting slot. The test cost is reduced and the detection efficiency is improved due to simple structure and easy operation. Moreover, the sample and the extraction solution are sealed in the test tube to prevent environmental pollution caused by spread of viruses.

2.20230030032METHODS AND SYSTEMS FOR TREATING OR PREVENTING PREGNANCY-RELATED HYPERTENSIVE DISORDERS
US 02.02.2023
Int.Class C07K 16/28
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
Appl.No 17783783 Applicant Aggamin, LLC Inventor Woo S. Joo

Disclosed are methods and apparatuses for treating a pregnancy related hypertensive disorder, such as pre-eclampsia and eclampsia, using ex vivo treatment with an anti-sEng antibody bound to a solid support in order to reduce blood levels of sEng. The present invention provides a method of treating or preventing a disorder associated with soluble Endoglin (sEng), such as a pregnancy-related hypertensive disorder, in a subject in need thereof comprising providing ex vivo to the subject anti-sEng antibodies or sEng-binding fragments thereof in an amount sufficient and for a time sufficient to decrease the subject's blood levels of sEng to treat or prevent the disorder associated with sEng in the subject.

3.20230030983FGFR/PD-1 COMBINATION THERAPY FOR THE TREATMENT OF CANCER
US 02.02.2023
Int.Class A61K 39/395
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
Appl.No 17655519 Applicant ASTEX THERAPEUTICS LTD Inventor Jayaprakash KARKERA

Provided herein are combination therapies for the treatment of cancer. In particular, the disclosed methods are directed to treatment of cancer in a patient comprising administering an antibody that blocks the interaction between PD-1 and PD-L1 and an FGFR inhibitor, wherein the antibody that blocks the interaction between PD-1 and PD-L1 and the FGFR inhibitor are administered if one or more FGFR variants are present in a biological sample from the patient.

4.20230037040BUILT-IN MULTI-ZONE FAST EVENLY MIXED SAMPLING DEVICE OF SCR OUTLET FLUE
US 02.02.2023
Int.Class G01N 1/22
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
1Sampling; Preparing specimens for investigation
02Devices for withdrawing samples
22in the gaseous state
Appl.No 17840647 Applicant HUANENG SHANGHAI SHIDONGKOU SECOND POWER PLANT Inventor Qingwen ZHANG

A built-in multi-zone fast evenly mixed sampling device of a Selective Catalytic Reduction (SCR) outlet flue is provided. The device includes: a sampling component, comprising a sampling branch pipe disposed on an outer wall of the SCR outlet flue, a sampling pool connected with the sampling branch pipe and a slanting branch pipe connected between the sampling pool and the sampling branch pipe, wherein a sampling probe is disposed on the sampling pool; a dust cleaning component, comprising a flange disposed on an upper end of the sampling branch pipe, a connecting line disposed on the flange and a suspension iron disposed on a lower end of the connecting line, wherein a lower end of the suspension iron extends out of the sampling branch pipe; and a replacement component, disposed at the sampling pool.

5.20230030639BIOLUMINESCENT SENSOR FOR ISOTHIOCYANATES
US 02.02.2023
Int.Class G01N 21/76
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
76Chemiluminescence; Bioluminescence
Appl.No 17386917 Applicant The United States of America, as represented by the Secretary of Agriculture Inventor CATHERINE L. REARDON

Disclosed are isothiocyanate (ITC)-detecting biosensors that utilize recombinant host cells containing an ITC responsive genetic element such as a saxA promoter, operably linked with a reporter element, such as a luxCDABE operon or ilux operon. Such biosensors can detect the presence of diverse ITCs in samples such as plant extracts, biofumigated soils and seed meal amended soils.

6.20230031535VISCOMETER AND A METHOD FOR DETERMINING A CONCENTRATION OF A COMPONENT IN A FLUID USING SUCH A VISCOMETER
US 02.02.2023
Int.Class G01N 11/14
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
11Investigating flow properties of materials, e.g. viscosity or plasticity; Analysing materials by determining flow properties
10by moving a body within the material
14by using rotary bodies, e.g. vane
Appl.No 17855404 Applicant Levitronix GmbH Inventor Daniel STEINERT

A viscometer for inline determination of the viscosity of a fluid includes a drive device and a measuring device including a housing and a chamber. The drive device includes a housing in which a stator is arranged. The stator has and having a plurality of coil cores delimited by an end face, and carrying a concentrated winding, and being a bearing and drive stator with which the rotor is magnetically driven without contact and magnetically levitated without contact with respect to the stator. A control device actuates the stator and determines the viscosity based on an operating parameter of the electromagnetic rotary drive.

7.20230032805APPARATUS AND METHOD FOR TESTING DYNAMIC SEALABILITY OF FLUID IN THE DOWNHOLE MINOR LEAKS
US 02.02.2023
Int.Class G01N 19/04
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
19Investigating materials by mechanical methods
04Measuring adhesive force between materials, e.g. of sealing tape, of coating
Appl.No 17388126 Applicant Zhejiang Ocean University Inventor Lin XU

A method and apparatus for determining the sealability of an oil & gas well sealant fluid, whereby a cylindrical cell assembly capable of withstanding high temperature and high pressure with an electromagnetic heater positioned radially outside the cell body while partly filled with said sealant fluid. A minor-leak assembly in connection to said cylindrical cell assembly allows said sealant fluid to continuously flow through a leak sample at a desired differential pressure, and the residual fluid is drained into said cell by a cycling pipeline system. The real-time pressure may be recorded to transmitted to a control system comprised of data acquisition and control units so as to monitor and measure the sealability of fluid in the downhole minor leaks.

8.20230031669HSD17B13 VARIANTS AND USES THEREOF
US 02.02.2023
Int.Class C12N 9/04
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
02Oxidoreductases (1.), e.g. luciferase
04acting on CHOH groups as donors, e.g. glucose oxidase, lactate dehydrogenase (1.1)
Appl.No 17930180 Applicant Regeneron Pharmaceuticals, Inc. Inventor Noura S. Abul-Husn

Provided are compositions related to HSD17B13 variants, including isolated nucleic acids and proteins related to variants of HSD17B13, and cells comprising those nucleic acids and proteins. Also provided are methods related to HSD17B13 variants. Such methods include methods for modifying a cell through use of any combination of nuclease agents, exogenous donor sequences, transcriptional activators, transcriptional repressors, and expression vectors for expressing a recombinant HSD17B13 gene or a nucleic acid encoding an HSD17B13 protein. Also provided are therapeutic and prophylactic methods for treating a subject having or at risk of developing chronic liver disease.

9.20230032587METHOD, APPARATUS, AND PROGRAM FOR DETERMINING CONDITION RELATED TO CAPTURED IMAGE OF CHARGED PARTICLE BEAM APPARATUS
US 02.02.2023
Int.Class H01J 37/22
HELECTRICITY
01BASIC ELECTRIC ELEMENTS
JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
37Discharge tubes with provision for introducing objects or material to be exposed to the discharge, e.g. for the purpose of examination or processing thereof
02Details
22Optical or photographic arrangements associated with the tube
Appl.No 17855888 Applicant Hitachi High-Tech Corporation Inventor Takahiro NISHIHATA

A method, an apparatus, and a program for more appropriately determining a condition for appropriately recognizing a semiconductor pattern are provided. A method for determining a condition related to a captured image of a charged particle beam apparatus including: acquiring, by a processor, a plurality of captured images, each of the captured images being an image generated by irradiating a pattern formed on a wafer with a charged particle beam, and detecting electrons emitted from the pattern, each of the captured images being an image captured according to one or more imaging conditions, the method further including: acquiring teaching information for each of the captured images; acquiring, by the processor, one or more feature determination conditions; calculating, by the processor, a feature for each of the captured images based on each of the feature determination conditions, at least one of the imaging condition and the feature determination condition being plural.

10.WO/2023/004474PRE-MIX TEST VESSEL
WO 02.02.2023
Int.Class G01N 1/38
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
1Sampling; Preparing specimens for investigation
28Preparing specimens for investigation
38Diluting, dispersing or mixing samples
Appl.No PCT/AU2022/050812 Applicant ATOMO DIAGNOSTICS LIMITED Inventor KETKAR, Rohit
The present invention provides a pre-mix device for use with a test unit. The device includes a vessel, an integrated reservoir of test fluid, and a discharge port. A sample may be received into the vessel and the test fluid may be discharged from the reservoir into the vessel, so that a mixture of the sample and the test fluid may be released from the discharge port to a test unit.