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Analysis

1.20230033215SYSTEM AND METHOD FOR ENHANCED ETHANOL PRODUCTION
US 02.02.2023
Int.Class C07C 29/84
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
29Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
74Separation; Purification; Stabilisation; Use of additives
76by physical treatment
80by distillation
84by extractive distillation
Appl.No 17875197 Applicant ICM, Inc. Inventor David VanderGriend

A system for producing ethanol comprises a rectifier column that receives a first process stream comprising from about 42% to about 60% ethanol, wherein the rectifier column purifies the first process stream to provide an ethanol product stream that is at least about 90% ethanol, and one or more evaporators configured to evaporate water from a second process stream, wherein the one or more evaporators generate vapor, and wherein at least a portion of the vapor supplies heat energy for separation of ethanol from water in the rectifier column.

2.20230033717PROCESS FOR TREATING WATERS, SOILS, SEDIMENTS AND/OR SLUDGES
US 02.02.2023
Int.Class C01B 25/37
CCHEMISTRY; METALLURGY
01INORGANIC CHEMISTRY
BNON-METALLIC ELEMENTS; COMPOUNDS THEREOF
25Phosphorus; Compounds thereof
16Oxyacids of phosphorus; Salts thereof
26Phosphates
37Phosphates of heavy metals
Appl.No 17864154 Applicant OASE GmbH Inventor Thorsten Muck

The present invention relates to a process for forming or obtaining vivianite in or from a phosphorus-containing waterbody, sediment and/or sludge, to an apparatus for obtaining vivianite from a phosphorus-containing waterbody, sediment and/or sludge, and to the use of a composition comprising at least one alkaline earth metal peroxide and a magnetic separating apparatus for obtaining vivianite from a phosphorus-containing waterbody, sediment and/or sludge.

3.WO/2023/004969ESTERASE MUTANT AND USE THEREOF
WO 02.02.2023
Int.Class C12N 9/16
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
14Hydrolases (3.)
16acting on ester bonds (3.1)
Appl.No PCT/CN2021/119423 Applicant ASYMCHEM LABORATORIES (TIANJIN) CO., LTD. Inventor HONG, Hao
Provided are an esterase mutant and the use thereof. The esterase mutant obtained by means of rational design and several rounds of evolution screening with enzymes on the basis of an amino acid sequence as shown in SEQ ID NO: 1 is changed in terms of protein structure and functions compared with a wild-type esterase; in practical use, the catalytic activity and/or stereoselectivity of the esterase mutant is greatly improved; and when a system contains some organic cosolvents, the esterase mutant still has relatively stable catalytic activity and/or stereoselectivity. In addition, the improvement of the catalytic activity and/or stereoselectivity of the esterase mutant reduces the use amount of the enzyme to a certain extent and reduces the difficulty of post-treatment, and therefore the esterase mutant is suitable for industrial production.
4.WO/2023/005779SUCROSE SYNTHETASE AND USE THEREOF
WO 02.02.2023
Int.Class C12N 9/10
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
10Transferases (2.)
Appl.No PCT/CN2022/106920 Applicant ABIOCHEM BIOTECHNOLOGY CO., LTD. Inventor WU, Yan
Provided are a sucrose synthetase and the use thereof. Compared with SEQ ID NO: 11, an amino acid sequence of the sucrose synthetase contains differences in amino acid residues selected from one or more of the following residue positions: an amino acid at position 36 being V, an amino acid at position 43 being E, an amino acid at position 179 being A, an amino acid at position 395 being R, an amino acid at position 447 being P, an amino acid at position 455 being L, and an amino acid at position 654 being R; and the sucrose synthetase has an activity not lower than that of a sucrose synthetase having an amino acid sequence as shown in SEQ ID NO: 11. By means of catalyzing the synthesis of rebaudioside A, rebaudioside D or rebaudioside M by using a glucosyltransferase and the sucrose synthetase in a combined manner, a cascade reaction is achieved, thereby providing a variety of possibilities for the selection of raw materials.
5.WO/2023/006109HIGHLY SPECIFIC GLYCOSYLTRANSFERASE FOR RHAMNOSE, AND USE THEREOF
WO 02.02.2023
Int.Class C12N 9/10
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
10Transferases (2.)
Appl.No PCT/CN2022/109355 Applicant SYNBIOTECH (SUZHOU) CO., LTD. Inventor YAN, Xing
Provided in the present invention are a highly specific glycosyltransferase for rhamnose, and the use thereof. A specific glycosyltransferase is disclosed in the present invention for the first time, which glycosyltransferase can catalyze rhamnosylation at a specific position of a substrate, and has high catalytic activity. Specifically, the specific glycosyltransferase of the present invention can specifically and efficiently catalyze the glycosylation of the C-6 position of a tetracyclic triterpene compound substrate on a first glycosyl so as to extend a rhamnose group. Also provided in the present invention is a mutant of the specific glycosyltransferase. The specific glycosyltransferase of the present invention has good specificity and high efficiency, can be applied to the construction of artificially synthesized ginsenoside, various new ginsenosides and derivatives thereof, and has good application value in the fields of pharmacy, etc.
6.WO/2023/008404REAGENT CONTAINING HUMANIZED ANTIBODY
WO 02.02.2023
Int.Class C07K 16/46
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
46Hybrid immunoglobulins
Appl.No PCT/JP2022/028698 Applicant DENKA COMPANY LIMITED Inventor ISHIKAWA Haruto
Provided are a reagent using an antibody that is capable of reducing a nonspecific reaction, a kit for measuring an antigen, and a method for measuring an antigen. An immunological assay reagent that contains a humanized antibody against a substance to be assayed.
7.WO/2023/006995COLLINOLACTONE BIOSYNTHESIS AND PRODUCTION
WO 02.02.2023
Int.Class C12N 15/52
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
11DNA or RNA fragments; Modified forms thereof
52Genes encoding for enzymes or proenzymes
Appl.No PCT/EP2022/071442 Applicant EBERHARD KARLS UNIVERSITÄT TÜBINGEN Inventor GROND, Stephanie
The present invention relates to isolated nucleic acids, proteins or peptides, sets thereof, gene clusters, expression vectors, host cells, biosynthesis methods, a process of genetic engineering for optimizing product yield, biotechnologically produced collinolactone and its derivatives, and their use for producing a pharmaceutical composition for the treatment, diagnosis and/or prophylaxis of diseases, more particularly neurodegenerative diseases.
8.20230035767METHOD FOR PRODUCING BIOPRODUCTS FRONT STREAMS OF ORGANIC MATERIAL
US 02.02.2023
Int.Class C12P 21/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
21Preparation of peptides or proteins
Appl.No 17792857 Applicant DRANCO, naamloze vennootschap Inventor Sylvia Marie-Pascale G Gildemyn

Method for producing bioproducts from streams of organic material, comprising the following steps: (i) the physical-biological pre-treating of the organic stream with water and one or more mechanical steps; (ii) setting the pH value of the mixture between pH 5 and pH 9; iii) adding an inoculum of a natural anaerobic culture that releases organic compounds; iv) a first separation step which splits the mixture into a solid and a liquid fraction, after which an anaerobic fermentation processes the solid fraction, with formation of biogas and digestate; v) an aerobic treatment of the separated liquid fraction with biological conversion of the organic compounds to a protein-rich bioproduct; vi) a second separation step with separation of the formed protein-rich bioproduct; vii) recirculating the liquid phase; viii) drying the formed protein-rich bioproduct, such that in the end a dry, protein-rich bioproduct is obtained as well as the bioproducts biogas and digestate.

9.WO/2023/006179METHOD TO PRODUCE RETINYL ACETATE
WO 02.02.2023
Int.Class C12P 23/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
23Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
Appl.No PCT/EP2021/070909 Applicant DSM IP ASSETS B.V. Inventor HOUSTON, Peter, Louis
The present invention is related to a novel process for production of retinyl acetate in a host cell, particularly oleaginous yeast such as e.g. Yarrowia, wherein the product purity could be increased with reduction of unwanted side- products. Particularly, the novel process comprises fermentation in the presence of ethanol, such as e.g. in a fed-batch fermentation process. Such process is especially useful in a biotechnological process for production of vitamin A.
10.WO/2023/004772FRUCTOSAMINE DEGLYCASE VECTOR, TRANSGENIC CELL LINE AND GENETICALLY ENGINEERED BACTERIUM EXPRESSING FRUCTOSAMINE DEGLYCASE, AND USE OF FRUCTOSAMINE DEGLYCASE
WO 02.02.2023
Int.Class C12P 7/40
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
7Preparation of oxygen-containing organic compounds
40containing a carboxyl group
Appl.No PCT/CN2021/109679 Applicant WUHAN BAI'ANHUIJI BIOTECHNOLOGY CO., LTD Inventor WANG, Huaiying
The present invention relates to a fructosamine deglycase vector, a transgenic cell line and a genetically engineered bacterium expressing fructosamine deglycase, and the use of fructosamine deglycase, which belong to the technical field of biological enzymatic production. Provided in the present invention is a method for catalyzing the transfer of an amino group from an amino donor compound to an amino acceptor compound. The method comprises: catalyzing the transfer of an amino group from an amino donor compound to an amino acceptor compound by means of using an enzyme (fructosamine deglycase), or an expression vector or a cloning vector expressing the enzyme, or a transgenic cell line expressing the enzyme, or a genetically engineered bacterium expressing the enzyme. The method of the present invention has the advantages of a sufficient substrate source, no limitations on raw materials, mild preparation conditions, low environmental pollution, a high reaction specificity, few impurities in the system, ease of downstream separation and purification, and a low production cost.