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Analysis

1.WO/2023/007985CELL TRANSPORT APPARATUS, METHOD FOR PRODUCING CULTURED CELLS, AND CELL TRANSPORT METHOD
WO 02.02.2023
Int.Class C12M 3/06
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
3Tissue, human, animal or plant cell, or virus culture apparatus
06with filtration, ultrafiltration, inverse osmosis or dialysis means
Appl.No PCT/JP2022/024581 Applicant NATIONAL AGRICULTURE AND FOOD RESEARCH ORGANIZATION Inventor TAKEZAWA Toshiaki
Provided is a cell transport apparatus (100) provided with a first container (110) having a first accommodation space (111) in which cultured cells (C) are accommodated and a second container (120) having a second accommodation space (121), the cell transport apparatus (100) being characterized in that the second container (120) is configured in such a manner that at least one sterilization filter (122) is provided at at least a part of the bottom surface of the second container (120) and the second container (120) can be attached to the upper part of the first container (110), and the first accommodation space (111) is surrounded by the first container (110) and the second container (120) and is communicated with the second accommodation space (121) through the at least one sterilization filter (122) in the state where the second container (120) is attached to the upper part of the first container (110).
2.WO/2023/005941CLOSED CELL CULTURING AND HARVESTING SYSTEM
WO 02.02.2023
Int.Class C12M 3/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
3Tissue, human, animal or plant cell, or virus culture apparatus
Appl.No PCT/CN2022/108034 Applicant SHANGHAI LONGEVITY CO., LTD. Inventor XIA, Tian
Provided is a bioreactor including a base and a lid. The base includes two opposing curved or convoluted surfaces, two opposing flat surfaces, a window disposed on one of the flat one of the flat surfaces, the window having a higher degree of transparency compared to other portions of the base, wherein images or videos of cells are captured through the window by non-invasive ISM device, and a rounded bottom. The lid is attachable to the base. The lid includes a shaft and a semipermeable membrane attached to the shaft. The semipermeable membrane is permeable to oxygen but impermeable to viruses and bacteria. The PAT-based online analysis directs the adaptive manipulations of bioreactor towards efficient, automated, and GMP-compliant clinical protocols of cell culture.
3.WO/2023/007500THREE-DIMENSIONAL TUMOR MODEL OF GLIOBLASTOMA AND BRAIN METASTASIS, METHODS OF MANUFACTURING SAME AND USES THEREOF
WO 02.02.2023
Int.Class C12N 5/071
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
07Animal cells or tissues
071Vertebrate cells or tissues, e.g. human cells or tissues
Appl.No PCT/IL2022/050824 Applicant RAMOT AT TEL-AVIV UNIVERSITY LTD. Inventor SATCHI-FAINARO, Ronit
A three dimensional (3D) model of a glioblastoma tumor made of a synthetic material and a plurality of cell types, including malignant cells and non-malignant cells of the tumor. Methods of forming the 3D tumor model are also provided, as well as systems in which the 3D tumor model can be perfused and fluidly connected to a medium containing immune cells and/or other cells and factors present in the tumor's microenvironment. Methods utilizing the 3D tumor model or the system in, for example, personalized therapy, are also provided.
4.20230034007METHODS OF PRESERVING TISSUES FOR TRANSPLANTATION
US 02.02.2023
Int.Class A01N 1/02
AHUMAN NECESSITIES
01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
1Preservation of bodies of humans or animals, or parts thereof
02Preservation of living parts
Appl.No 17791187 Applicant The Regents of the University of California Inventor Koichi Masuda

Provided herein are systems and methods for preserving and transporting tissues for transplantation. In particular, tissue to be implanted is encapsulated in an alginate gel, which is exposed to culture medium to improve cell viability and suppress inflammatory factors during long-term storage and transport.

5.20230032623Tumor-on-a-chip
US 02.02.2023
Int.Class G01N 33/50
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
Appl.No 17816152 Applicant NEW YORK UNIVERSITY Inventor Weiqiang Chen

The present invention provides devices that replicate tumor microenvironments in a microfluidic chip. The devices can be used to model certain disease states related to tumor microenvironments. The devices can be adapted to replicate tumor microenvironments from patient-specific cells such that treatment conditions can be modeled and tailored to individual patients. In some embodiments, the devices are suitable for evaluating cancer therapies on a patient-specific basis.

6.WO/2023/008076GENETICALLY MODIFIED POTATO WITH REDUCED GLYCOALKALOID AND METHOD FOR PRODUCING SAME
WO 02.02.2023
Int.Class A01H 1/00
AHUMAN NECESSITIES
01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
HNEW PLANTS OR PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
1Processes for modifying genotypes
Appl.No PCT/JP2022/026124 Applicant KANEKA CORPORATION Inventor NAGIRA, Yozo
This genetically modified potato is characterized in that a deletion, an insertion, or a substitution is introduced into the CSLM gene, and this method for producing a genetically modified potato is characterized by comprising a step of introducing a deletion, an insertion, or a substitution into the CSLM gene of a potato.
7.WO/2023/008692CELL EXTRUSION SYSTEM, AND CELL EXTRUSION METHOD USING SAME
WO 02.02.2023
Int.Class C12M 1/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
Appl.No PCT/KR2022/006147 Applicant MDIMUNE INC. Inventor JUNG, Jik Han
The present invention relates to a cell extrusion system and a cell extrusion method using same, the cell extrusion system comprising: a filter provided with a porous membrane and a holder which supports the membrane; a tube in which a cell suspension flows, the tube being connected to both sides of the filter such that the cell suspension flows through the membrane; and an extrusion unit provided with a pump that is connected to one side of the tube to transport the cell suspension. The present invention has the effect of making it possible to mass-produce cell-derived vesicles reliably and economically.
8.WO/2023/009772BAFFLE FOR MICROCAVITY CELL CULTURE VESSELS
WO 02.02.2023
Int.Class C12M 1/24
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
24tube or bottle type
Appl.No PCT/US2022/038751 Applicant CORNING INCORPORATED Inventor CLOUTIER, Thomas Albert
A baffle (130) configured to be disposed in a cell culture vessel is provided. The cell culture vessel (100) may comprise a vessel body (101) comprising a bottom wall (110) and a plurality of side walls (107) that define a cell culture chamber, the bottom wall comprising a cell culture surface (111). The baffle (130) may be configured to be disposed parallel to the cell culture surface (111) within the vessel body, the baffle comprising a first baffle crossbar (133) extending across a length of the cell culture surface; a second baffle crossbar intersecting (135) the first baffle crossbar; and a third crossbar disposed (137) at an end of the first baffle crossbar.
9.WO/2023/009007PREPARATION OF CELL-CONTAINING HYDROGEL.
WO 02.02.2023
Int.Class C12M 3/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
3Tissue, human, animal or plant cell, or virus culture apparatus
Appl.No PCT/NL2022/050452 Applicant MOSA MEAT B.V. Inventor BREEMHAAR, Jonathan Jan
A method of preparing a cell-containing hydrogel for use in the production of cultured meat is provided, along with examples of device for performing the method. The method comprises steps of positioning a central body inside a circumferential member, thereby forming an annular volume, filling the annular volume with a cell-containing fluid, moving the central body relative to the circumferential member such that the central body moves through an outlet opening of the circumferential member, thereby creating an access area between the central body and the circumferential member, and exposing the access area to a cross-linking fluid to allow crosslinking of the cell-containing fluid to obtain a cell-containing hydrogel.
10.WO/2023/008108CONTAINER AND CELL TRANSPORT APPARATUS
WO 02.02.2023
Int.Class C12M 1/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
Appl.No PCT/JP2022/026658 Applicant NATIONAL AGRICULTURE AND FOOD RESEARCH ORGANIZATION Inventor TAKEZAWA Toshiaki
A container for observation of cells, the container comprising a bottom wall and a lateral wall, wherein an observation surface is formed in the bottom wall, and the observation surface has, displayed therein, a reference line and an indication part indicating a specific region near the reference line.