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Analysis

1.20230033215SYSTEM AND METHOD FOR ENHANCED ETHANOL PRODUCTION
US 02.02.2023
Int.Class C07C 29/84
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
29Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
74Separation; Purification; Stabilisation; Use of additives
76by physical treatment
80by distillation
84by extractive distillation
Appl.No 17875197 Applicant ICM, Inc. Inventor David VanderGriend

A system for producing ethanol comprises a rectifier column that receives a first process stream comprising from about 42% to about 60% ethanol, wherein the rectifier column purifies the first process stream to provide an ethanol product stream that is at least about 90% ethanol, and one or more evaporators configured to evaporate water from a second process stream, wherein the one or more evaporators generate vapor, and wherein at least a portion of the vapor supplies heat energy for separation of ethanol from water in the rectifier column.

2.WO/2023/005119SYSTEM DEVICE FOR AUTOMATED SUSTAINABLE LARGE-SCALE 3D CELL PRODUCTION
WO 02.02.2023
Int.Class C12M 1/38
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
36including condition or time responsive control, e.g. automatically controlled fermentors
38Temperature-responsive control
Appl.No PCT/CN2021/139756 Applicant SHANGHAI NATIONAL ENGINEERING RESEARCH CENTER FOR NANOTECHNOLOGY LTD. Inventor CUI, Daxiang
A system device for automated sustainable large-scale 3D cell production and an application thereof, said device comprising an intelligent gas distribution system, a production system, and a collection system; the intelligent gas distribution system can meet gas requirements for cell culture; and the production system comprises production cells, a temperature control system, a microcarrier, an agitator, and a delivery pump.
3.WO/2023/006576METHOD FOR PRODUCING A BIOPRODUCT
WO 02.02.2023
Int.Class C12M 1/26
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
26Inoculator or sampler
Appl.No PCT/EP2022/070502 Applicant SARTORIUS STEDIM BIOTECH GMBH Inventor SABALLUS, Martin
The invention is directed to a method for producing a bioproduct using a bioprocess installation (1 ), wherein the bioprocess installation (1) comprises an electronic process control (2) and a bioprocess unit (3), wherein the bioprocess unit (3) comprises a receptacle (4), a clarification unit (5) with a centrifuge (6) and a chromatography unit (8) with a chromatograph (10), wherein cell broth obtained from the receptacle (4) is being lead through the clarification unit (5) and the chromatography unit (8) sequentially in a liquid stream (9), wherein the clarification unit (5) with its centrifuge (6) is being operated in a centrifugation cycle comprising centrifugation steps, such as loading-, washing- and discharging-steps, wherein the chromatography unit (8) with its chromatograph (10) is being operated in a chromatography cycle comprising chromatography steps, such as equilibration-, loading-, washing-, elution- and regeneration¬ steps, It is proposed that particle depletion between the liquid stream section leaving the clarification unit (5) and the liquid stream section leaving the chromatography unit (8) is less than 10% in particle concentration and that the execution of the steps assigned to the centrifugation cycle and the execution of the steps assigned to the chromatography cycle are at least partly being synchronized with each other by the electronic process control (2) in synchronization routines (13) based on assigned synchronization strategies (14).
4.WO/2023/008270BIO-RELATED SUBSTANCE EXTRACTING DEVICE AND PROCESSING SYSTEM
WO 02.02.2023
Int.Class G01N 1/28
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
1Sampling; Preparing specimens for investigation
28Preparing specimens for investigation
Appl.No PCT/JP2022/028147 Applicant UNIVERSAL BIO RESEARCH CO., LTD. Inventor TAJIMA Hideji
An extracting device 200 comprises: a plurality of extraction vessels 210 for holding a solution containing magnetic particles and a sample; an oscillating mechanism 220 for causing the extraction vessels 210 to oscillate; a magnetic body which exerts a magnetic force on the extraction vessels 220; magnet moving mechanisms 258, 259 for moving the magnetic body between a contacting position in which the magnetic body is in contact with the extraction vessels 210 and a non-contacting position in which the magnetic body is not in contact with the extraction vessels 210; a temperature regulating unit for regulating the temperature of the extraction vessels 210; temperature regulating unit moving mechanisms 248, 249 for moving the temperature regulating unit between a contacting position in which the temperature regulating unit is in contact with the extraction vessels 210 and a non-contacting position in which the temperature regulating unit is not in contact with the extraction vessels 210; and a control portion for controlling the operation of each mechanism.
5.WO/2023/008525CELL IMAGE ANALYSIS METHOD
WO 02.02.2023
Int.Class C12M 1/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
Appl.No PCT/JP2022/029115 Applicant SHIMADZU CORPORATION Inventor SAWADA, Ryuji
This cell image analysis method comprises: a step for acquiring a cell image (10) in which a cell (90) is shown; a step for generating, by performing filter processing on the cell image, a background component image (14) from which a distribution of luminance components of the background (91) is extracted; a step for generating, on the basis of the cell image and the background component image, a corrected cell image (11) in which correction has been performed in order to reduce luminance unevenness; and a first estimation step for estimating whether the cell in the image is a normal cell or an abnormal cell by using the corrected cell image and a trained model (6) trained with cell analysis.
6.WO/2023/007985CELL TRANSPORT APPARATUS, METHOD FOR PRODUCING CULTURED CELLS, AND CELL TRANSPORT METHOD
WO 02.02.2023
Int.Class C12M 3/06
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
3Tissue, human, animal or plant cell, or virus culture apparatus
06with filtration, ultrafiltration, inverse osmosis or dialysis means
Appl.No PCT/JP2022/024581 Applicant NATIONAL AGRICULTURE AND FOOD RESEARCH ORGANIZATION Inventor TAKEZAWA Toshiaki
Provided is a cell transport apparatus (100) provided with a first container (110) having a first accommodation space (111) in which cultured cells (C) are accommodated and a second container (120) having a second accommodation space (121), the cell transport apparatus (100) being characterized in that the second container (120) is configured in such a manner that at least one sterilization filter (122) is provided at at least a part of the bottom surface of the second container (120) and the second container (120) can be attached to the upper part of the first container (110), and the first accommodation space (111) is surrounded by the first container (110) and the second container (120) and is communicated with the second accommodation space (121) through the at least one sterilization filter (122) in the state where the second container (120) is attached to the upper part of the first container (110).
7.WO/2023/008180IMAGE PROCESSING METHOD, COMPUTER PROGRAM, AND RECORDING MEDIUM
WO 02.02.2023
Int.Class C12M 1/34
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
34Measuring or testing with condition measuring or sensing means, e.g. colony counters
Appl.No PCT/JP2022/027419 Applicant SCREEN HOLDINGS CO., LTD. Inventor TOKISUE, Shogo
This image processing method comprises the steps of: acquiring a plurality of original images obtained by capturing a sample including cells at mutually different depths of focus; creating a composite image including images of the sample included in the respective original images in one image plane; and inputting the composite image to a classification model constructed in advance to acquire an output thereof. The classification model is constructed by performing machine learning in advance using a teacher image including, in one image plane, a plurality of images that are images of the same cell or cell cluster and are mutually different in depth of focus. The present invention makes it possible to automatically acquire information relating to a sample including cells from a plurality of images obtained by capturing the sample at mutually different depths of focus.
8.WO/2023/007805TEST METHOD AND TEST SYSTEM
WO 02.02.2023
Int.Class C12M 1/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
Appl.No PCT/JP2022/009372 Applicant SHIMADZU CORPORATION Inventor HARADA, Tomoyuki
One embodiment of a test method according to the present invention is carried out through specimen pooling using a test system equipped with a pre-treatment device for mixing a plurality of individual specimens to prepare a pooled specimen, a test device for analyzing the pooled specimen or an individual specimen, a management terminal capable of communicating with each of the pre-treatment device and the test device, a database that can be accessed from the management terminal, and a display unit, wherein: before preparation of the pooled specimen, software for pre-treatment device management that is installed in the management terminal has a step for receiving input of specimen information relating to the individual specimens and the pooled specimen through a user operation, a step for saving the received specimen information in the database, and a step for displaying the results of analysis of one or a plurality of pooled specimens on the display unit (S16); and when at least one pooled specimen is positive, the software for test device management that is installed in the management terminal has a specimen designation step (S18) for receiving designation or selection of a specific pooled specimen, and a specimen information input step (S19) for acquiring specimen information about the plurality of individual specimens associated with the designated or selected pooled specimen from the database, inserting the acquired specimen information at a prescribed position in a specimen information input screen image for setting the specimen information on a specimen to be tested, and displaying the specimen information on the display unit.
9.WO/2023/005941CLOSED CELL CULTURING AND HARVESTING SYSTEM
WO 02.02.2023
Int.Class C12M 3/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
3Tissue, human, animal or plant cell, or virus culture apparatus
Appl.No PCT/CN2022/108034 Applicant SHANGHAI LONGEVITY CO., LTD. Inventor XIA, Tian
Provided is a bioreactor including a base and a lid. The base includes two opposing curved or convoluted surfaces, two opposing flat surfaces, a window disposed on one of the flat one of the flat surfaces, the window having a higher degree of transparency compared to other portions of the base, wherein images or videos of cells are captured through the window by non-invasive ISM device, and a rounded bottom. The lid is attachable to the base. The lid includes a shaft and a semipermeable membrane attached to the shaft. The semipermeable membrane is permeable to oxygen but impermeable to viruses and bacteria. The PAT-based online analysis directs the adaptive manipulations of bioreactor towards efficient, automated, and GMP-compliant clinical protocols of cell culture.
10.WO/2023/008219METHOD AND APPARATUS FOR RAPIDLY TESTING MICROORGANISM
WO 02.02.2023
Int.Class C12Q 1/04
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
02involving viable microorganisms
04Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
Appl.No PCT/JP2022/027760 Applicant HITACHI HIGH-TECH CORPORATION Inventor ISHIMARU Masako
The present invention provides a technique for rapidly detecting a microorganism in a sample. Specifically, the present invention relates to a method for detecting a microorganism in a sample, the method comprising: a step for preparing a test sample; a step for dividing the test sample to prepare at least two partial samples; a step for applying different treatments for a first partial sample and a second partial sample; a step for measuring, in the first partial sample, a marker substance present in the microorganism or secreted by the microorganism to obtain a first measured value; a step for measuring, in the second partial sample, the marker substance to obtain a second measured value; a step for calculating a threshold value from the first measured value; and a step for comparing the second measured value with the threshold value to determine whether the sample contains the microorganism.