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Results 1-10 of 158 for Criteria:ALLNAMES:("howard university") Office(s):all Language:EN Stemming: true maximize
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TitleCtrPubDate
Int.ClassAppl.NoApplicantInventor
1. 20170240698 Biodegradable Stealth Polymeric Particles Fabricated Using The Macromonomer Approach By Free Radical Dispersion PolymerizationUS24.08.2017
C08G 63/78
15590239Emmanuel Oyekanmi AkalaEmmanuel Oyekanmi Akala

The present invention is directed to a crosslinked or non-crosslinked polymer particle, wherein the crosslinked polymer particle comprises a copolymer of poly(alkylene glycol-graft-lactate) that is crosslinked by at least one hydrolysable monomer. Another embodiment of the present invention is a polymer particle comprising a crosslinked polymer particle that is a product of starting materials comprising (a) a hydrophilic monomer, (b) a hydrophobic monomer, and (c) a hydrolysable crosslinking agent. Another embodiment of the present invention is a polymer particle comprising, a crosslinked copolymer comprising structures represented by Formulas (I), (II), and (III), where Formulas (I), (II) and (III) are defined in the specification. Yet other embodiments of the present invention include a method of preparing a methacrylate terminated macromonomer, a method of preparing a crosslinking agent, and a method of preparing a therapeutic agent loaded nanosphere by dispersion polymerization.


2. 112015010675 copolímeros em bloco para a proteção do esmalte do denteBR11.07.2017
A61K 6
112015010675COLGATE-PALMOLIVE COMPANYJAMES W. MITCHELL
resumo“copolímeros em bloco para a proteção do esmalte do dente”aqui são descritos copolímeros de bloco tendo blocos hidrófobos e blocos hidrófilos que são eficazes na ligação à superfície do tecido duro; composições compreendendo os mesmos, bem como métodos para produzir e utilizar os mesmos.

3. 112014022863 síntese química verde do medicamento amodiaquina e de seus análogos no tratamento da maláriaBR20.06.2017
A61K 31
112014022863Howard UniversityAmol Anant Kulkarni
síntese de química verde do medicamento amodiaquina e de seus análogos no tratamento da malária o presente pedido de patente se refere a processos fornecidos para uma síntese de química verde em um único recipiente de amodiaquina e análogos de amodiaquina. os processos têm um menor impacto ambiental, menor custo de investimento, quantidades reduzidas de subprodutos e impurezas, e um tempo mais curto de síntese em comparação com os atuais processos de síntese convencionais. os processos reduzem o número total de etapas na síntese de quatro a cinco para até duas, simplificando, desta forma, a produção; e permitem que um número reduzido de solventes e reagentes seja utilizado na produção, reduzindo, assim, os resíduos gerados na síntese. os processos podem reduzir os resíduos para cerca de 3-5 quilogramas de resíduos gerados por quilograma de produto produzido; e, surpreendentemente, melhorar o rendimento total de 60-65% para mais de 90% em comparação com os atuais processos de síntese convencionais para amodiaquina e seus análogos.1/1

4. WO/2017/100192 SYSTEM AND METHOD FOR PROTECTION OF ELECTRONIC BOX UNDER LIGHTNING STRIKEWO15.06.2017
H02H 9/02
PCT/US2016/065152HOWARD UNIVERSITYMOMOH, James
An airport lighting system includes one or more lighting elements, a transient protection apparatus, and one or more electrical control cabinets. The transient protection apparatus is coupled to the one or more lighting elements. One or more electrical control cabinets are coupled to the transient protection apparatus. Each of the control cabinets produces one or more of control and power signals that are effective to operate the one or more lighting elements. The transient protection apparatus is configured to provide protection for one or more of the electrical control cabinets and the one or more lighting elements from electrical surges.

5. WO/2017/087835 COMPOSITION, METHOD OF MANUFACTURE, AND USE OF SITE-SPECIFIC DELIVERY OF BRUCEOLIDES FOR TREATMENT OF CANCER AND OTHER DISEASESWO26.05.2017
A61K 31/35
PCT/US2016/062833HOWARD UNIVERSITYADESINA, Simeon Kolawole
Disclosed are bruceolides for the treatment of cancer, and other diseases, selectively targeting unwanted cells. The disclosed bruceolides may include a site specific cleavable moiety inhibiting the chemotoxic activity until cleaved, i.e., removed, within and/or near a cancer to be treated. As to facilitate selective delivery to cancer tumors, the disclosed bruceolides may be loaded into, attached to or otherwise carried by nanoparticles.

6. 20170008839 BENZENDE SULFONAMIDE DERIVATIVES AS HIV INTEGRASE INHIBITORSUS12.01.2017
C07C 311/41
15114289HOWARD UNIVERSITYXiang Simon WANG

Methods for treating retroviral infection or inhibiting HIV integrase in target cells or in a patient involve administering to target cells or to a patient in need of treatment an effective amount of at least one having a disulfonamide scaffold which is represented by the formula:

embedded image

wherein, independent of each other,

    • each X independently represents hydrocarbyl, halogeno, amino, substituted amino, or alkoxy, wherein substituted amino is represented by —NR3,R4 wherein R3 and R4, are not both hydrogen and independently represent alkyl or alkenyl,
    • n is an integer of 0, 1, 2, or 3,
    • each Y independently represents hydrocarbyl, halogeno, amino, substituted amino or alkoxy,wherein substituted amino is represented by —NR3,R4 wherein R3 and R4, are not both hydrogen and independently represent alkyl or alkenyl,
    • m is an integer of 0, 1, 2, or 3, and
    • R represents di-valent hydrocarbyl, substituted or unsubstituted.


7. 20160347739 5-OXOPYRROLIDINE DERIVATIVES AS HIV INTEGRASE INHIBITORSUS01.12.2016
C07D 403/06
15220049Xiang Simon WANGXiang Simon WANG

A method for treating against HIV, such as by inhibiting HIV integrase, in target cells or in a patient involves administering to target cells or to a patient in need of treatment an effective amount of at least one compound having an N-indol heteroarylcarboxamide scaffold which compound is represented by the formula:

embedded image

wherein, independent of each other,

    • R independently represents hydrocarbyl, halogeno, amino, substituted amino, or alkoxy,
    • R1 represents di-valent hydrocarbyl, substituted or unsubstituted, and
    • R2 represents an ether moiety.


8. 20160308996 Apparatus and Method for Context-Aware Mobile Data ManagementUS20.10.2016
H04L 29/08
15189160Legand L. Burge, IIILegand L. Burge, III

The context of a first electronic device is automatically determined, and the first electronic device has a display unit. Information is displayed at the display unit based upon the context. The context is transmitted from the first electronic device to a second electronic device, and from the first electronic device and to a third electronic device. A first consistency of information is maintained between the first electronic device and a second electronic device based at least upon the context, and a second consistency is maintained between the first electronic device and a third electronic device based at least upon the context. The first consistency is greater than the second consistency.


9. WO/2016/154043 POLYSACCHARIDE-POLYAMINE COPOLYMERS FOR REMOVAL OF PHOSPHATEWO29.09.2016
A61K 31/715
PCT/US2016/023237HOWARD UNIVERSITYMITCHELL, James W.
Covalently cross-linked copolymers are described herein. More specifically, polysaccharide-polyamine copolymeric matrices or structures and cationic copolymeric matrices are described herein. The polysaccharide-polyamine copolymers, when protonated, can form cationic copolymeric matrices having exceptionally high densities of cationic sites. In one form, the covalently cross-linked copolymers provide a three-dimensional structure, especially when hydrated.

10. WO/2016/154048 MICROCARRIERS, MATRICES AND SCAFFOLDS FOR CULTURING MAMMALIAN CELLS AND METHODS OF MANUFACTUREWO29.09.2016
A61K 31/715
PCT/US2016/023248HOWARD UNIVERSITYMITCHELL, James W.
Microcarriers, matrices and scaffolds for growing mammalian cells are provided which include copolymer particles and matrices comprising of polysaccharide-polyamine copolymers. The copolymeric particles and matrices have a pore size of at least 50 microns and permit the mammalian cells to grow both on an exterior surface of the particles and matrices and within an interior of the particles and matrices. Methods for making such microcarriers, matrices and scaffolds, and compositions are also provided. Methods for growing mammalian cells utilizing such microcarriers, matrices and scaffolds and compositions are also provided.


Results 1-10 of 158 for Criteria:ALLNAMES:("howard university") Office(s):all Language:EN Stemming: true maximize
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