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Analysis

1.WO/2022/012607INCUBATOR
WO 20.01.2022
Int.Class C12M 1/36
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
36including condition or time responsive control, e.g. automatically controlled fermentors
Appl.No PCT/CN2021/106395 Applicant SHANGHAI WOLWO CELLTEK CO., LTD. Inventor HU, Gengxi
Provided in the present invention is an incubator capable of producing pressure fluctuations. The incubator comprises an incubator body and a variable pressure apparatus, the incubator body having a variable pressure interface, the variable pressure apparatus being connected to the incubator body by means of the variable pressure interface, and the variable pressure apparatus being used for inputting fluctuating or constant air pressure into the incubator body.
2.WO/2022/013057BIOPROCESSING SYSTEM AND TUBING AND COMPONENT MANAGEMENT APPARATUS FOR A BIOPROCESSING SYSTEM
WO 20.01.2022
Int.Class C12M 3/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
3Tissue, human, animal or plant cell, or virus culture apparatus
Appl.No PCT/EP2021/068988 Applicant GLOBAL LIFE SCIENCES SOLUTIONS USA LLC Inventor STEGNER, Elizabeth
A component management apparatus for a bioprocessing system includes a frame having a plurality of segments, including at least a first segment and a second segment pivotably connected to the first segment such that at least the second segment is movable between a closed position and an open position, and at least one mounting bracket connected to the frame for connection of a bioprocess component.
3.WO/2022/011706BIOCHEMICAL REACTION APPARATUS AND APPLICATION THEREOF
WO 20.01.2022
Int.Class B01L 3/14
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
3Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
14Test tubes
Appl.No PCT/CN2020/102791 Applicant MGI TECH CO., LTD. Inventor ZHAO, Jing
A biochemical reaction apparatus (100), comprising a reaction vessel (10) and a separation portion (30). The reaction vessel (10) comprises a first end wall (11) and a second end wall (13) which are arranged oppositely, and a side wall (15) connecting the first end wall (11) and the second end wall (13); the first end wall (11), the second end wall (13), and the side wall (15) define a sealed cavity (16). The separation portion (30) is provided on the side wall (15) and separates the sealed cavity (16) into a first reaction chamber (161) and a second reaction chamber (163); the first reaction chamber (161) is used for containing a first reaction reagent, and the second reaction chamber (163) is used for containing a second reaction reagent. The separation portion (30) can be opened to mix the second reaction reagent with the first reaction reagent. Also provided is a CRISPR technology-based detection system comprising the biochemical reaction apparatus (100).
4.WO/2022/014436CELL CULTURING CONTAINER, METHOD FOR MANUFACTURING CELL CULTURING CONTAINER, CELL PRODUCTION METHOD, CELL CULTURING DEVICE, AND CELL CULTURING JIG
WO 20.01.2022
Int.Class C12M 1/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
Appl.No PCT/JP2021/025607 Applicant TOYO SEIKAN GROUP HOLDINGS, LTD. Inventor KOSEKI Osamu
Provided is a cell culturing container that is for culturing cells at a high density and has excellent gas permeability and strength. A bag-like, closed-system cell culturing container 1 has at least one port and is formed from opposing planar members 11. At least one of the planar members 11 comprises a gas permeable film, an outer surface of at least one gas permeable film has protrusions 111 of a shape that differs from an inner surface shape of the gas permeable film, and a culturing space S for culturing cells is provided on the inner surface side of the gas permeable film. When the gas permeable film is caused to contact a planar surface, a space that can be ventilated is formed between the gas permeable film and the planar surface by virtue of the presence of the protrusions 111.
5.WO/2022/014622METHOD FOR PRODUCING CARDIOMYOCYTE CELL MASS
WO 20.01.2022
Int.Class C12N 5/071
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
07Animal cells or tissues
071Vertebrate cells or tissues, e.g. human cells or tissues
Appl.No PCT/JP2021/026374 Applicant KANEKA CORPORATION Inventor KAWAI Yoshikazu
The present invention addresses the problem of conveniently acquiring a large amount of a cardiomyocyte cell mass within a short period of time from single-celled cardiomyocytes with the use of neither a special medium component nor a container having a complicated shape, nor a micro size container. This problem can be solved by a method for producing a cardiomyocyte cell mass, said method being characterized by comprising allowing single-celled cardiomyocytes to flow in an acyclic container under suspension conditions and thus inducing the aggregation of the cells together. Also, the aforesaid problem can be solved by a method for producing a cardiomyocyte cell mass, said method being characterized in that the single-celled cardiomyocytes have a history of stabilization culture after thawing.
6.WO/2022/013166GROWTH MODULATION
WO 20.01.2022
Int.Class B01L 3/00
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
3Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
Appl.No PCT/EP2021/069369 Applicant BIOMILLENIA SAS Inventor DAJKOVIC, Aleksander
The present invention uses microfluidics droplets for studying the growth dynamics of communities of bacteria in the presence of various perturbations such as various chemicals or other microorganisms and to establish microbial assemblies model which is representative of a microbiota of interest and to examine their growth dynamics after perturbations such as with an array of chemicals or other microorganisms. In particular, the present invention refers to a method and apparatus for assessing the effect of a chemical or biological substance on the growth of microorganisms.
7.WO/2022/016136MICROFLUIDIC SYSTEMS FOR MULTIPLE BIOREACTORS AND APPLICATIONS OF SAME
WO 20.01.2022
Int.Class C12M 3/06
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
3Tissue, human, animal or plant cell, or virus culture apparatus
06with filtration, ultrafiltration, inverse osmosis or dialysis means
Appl.No PCT/US2021/042141 Applicant VANDERBILT UNIVERSITY Inventor SCHAFFER, David K.
A fluidic device includes a fluidic chip having a fluidic network comprising a plurality of fluidic channels in fluidic communication with a plurality of input ports, at least one output port, and at least one sensing port; and an actuator configured to engage with the fluidic network to control each fluidic channel to switch between an open state in which fluidic flow through said fluidic channel is permitted and a closed state in which no fluidic flow through said fluidic channel is permitted, so as to selectively collect fluid from multiple inputs via the plurality of input ports, and direct either all of the multiple inputs to the at least one output port, or all but a single selected input to the at least one output port and the single selected input to the at least one sensing port to which an analytical instrument is operably connected.
8.WO/2022/016143MICROFLUIDIC SYSTEMS FOR MULTIPLE BIOREACTORS AND APPLICATIONS OF SAME
WO 20.01.2022
Int.Class C12M 1/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
Appl.No PCT/US2021/042179 Applicant VANDERBILT UNIVERSITY Inventor REISERER, Ronald S.
A fluidic system includes a fluid distribution network, and a fluid collection and sampling network; a plurality of fluidic modules fluidically coupled between the fluid distribution network and the fluid collection and sampling network in parallel; a systemic circulation and mixing reservoir; and a first pump, and a second pump, wherein the first pump is fluidically coupled between the systemic circulation and mixing reservoir and the fluid distribution network for withdrawing media from the systemic circulation and mixing reservoir and delivering the media to the fluid distribution network; and wherein the second pump is fluidically coupled between the fluid collection and sampling network and a sample vial for withdrawing effluent of the plurality of fluidic modules from the fluid collection and sampling network and delivering the effluent to one or more sample vials.
9.WO/2022/013607CELL MICROPORATOR
WO 20.01.2022
Int.Class C12M 3/06
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
3Tissue, human, animal or plant cell, or virus culture apparatus
06with filtration, ultrafiltration, inverse osmosis or dialysis means
Appl.No PCT/IB2020/059497 Applicant UAB "FEMTIKA“ Inventor JONUŠAUSKAS, Linas
The invention falls within the field of biomedicine, more specifically cell transfection devices. A cell microporator consisting of a fluid microchannel (1) and mechanical action elements housed therein, which are made as two rotating rollers (2, 2a, 2b) (synonym "rolls") and are mounted in the recesses (1a, 1b) of the microchannel (1) at a distance from each other less than the size of the cells to be processed, one or both of the rollers (2, 2a, 2b) are made with teeth (3) or spikes (5) (needles), the rollers being passive, rotated by the flowing liquid and are in contact with the cells on one side. Various roller-shaped options are offered: cylindrical, convex-concave (pair), concave, stepped cylindrical.
10.WO/2022/011729MULTI-EFFICIENCY ACCURATE ELECTRICAL STIMULATION DEVICE AND METHOD FOR EGG CELL
WO 20.01.2022
Int.Class C12M 3/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
3Tissue, human, animal or plant cell, or virus culture apparatus
Appl.No PCT/CN2020/103160 Applicant SOOCHOW UNIVERSITY Inventor HUANG, Haibo
Disclosed in the present invention is a multi-efficiency accurate electrical stimulation device for an egg cell. The multi-efficiency accurate electrical stimulation device comprises: a base; an electrical stimulation mechanism comprising two first electrical stimulation assemblies and two second electrical stimulation assemblies, wherein each first electrical stimulation assembly comprises a liquid metal capillary micro-needle electrode and a first needle holding instrument connected to the liquid metal capillary micro-needle electrode, and each second electrical stimulation assembly comprises a metal parallel plate micro-electrode and a second needle holding instrument connected to the metal parallel plate micro-electrode; a cell pose adjusting chip mounted on the base and configured for adjusting the pose of a cell; and a rotating mechanism mounted on the base, connected to the cell pose adjusting chip and configured for driving the cell pose adjusting chip to rotate. Further disclosed is a multi-efficiency accurate electrical stimulation method for an egg cell. According to the present invention, accurate electrical stimulation can be carried out on specific parts of an egg cell at different stages during an entire cloning process, multiple effects of targeted electrical stimulation are achieved at all stages of a somatic cell cloning process, and the success rate of the entire somatic cell cloning process is increased.