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IC:A61K39/12

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Analysis

1 / 3,275
1.WO/2025/143714DIAGNOSTIC KIT FOR BOVINE DIARRHEA-CAUSING VIRUS
WO - 03.07.2025
Int.Class C07K 14/005
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
005from viruses
 Appl.No PCT/KR2024/020949 Applicant BOREDA BIOTECH Inventor CHOI, Dong Ok
The present invention relates to a diagnostic kit for bovine viral diarrhea virus (BVDV), which enables rapid on-site identification and diagnosis of BVDV1 and BVDV2, which are genotypes of the BVD virus that are pathogens causing bovine diarrhea, within a short time of approximately 15 minutes.
2.WO/2025/144655IDENTIFICATION OF ACTIVE CORONAVIRUS INFECTION BY TARGETING THE NEGATIVE RNA STRAND
WO - 03.07.2025
Int.Class C12N 15/113
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
11DNA or RNA fragments; Modified forms thereof
113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
 Appl.No PCT/US2024/060772 Applicant HOWARD UNIVERSITY Inventor ULLAH, Hemayet
A method for detecting a coronavirus in a sample, the method containing i) isolating RNA from a sample; ii) contacting the isolated RNA with a first primer in the presence of a reverse transcriptase and dNTP under conditions permissive for cDNA synthesis, thereby generating cDNA; iii) contacting the cDNA with forward and reverse primers in the presence of a DNA polymerase and dNTP under condition permissive for cDNA amplification, thereby generating an amplified product, and iv) identifying the amplified product, thereby detecting the presence or absence of the virus, wherein the first primer binds to or hybridizes with a negative-strand RNA molecule produced by the virus.
3.WO/2025/140246MPOX VIRUS NUCLEIC ACID VACCINE
WO - 03.07.2025
Int.Class C07K 19/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
19Hybrid peptides
 Appl.No PCT/CN2024/142122 Applicant SUZHOU ABOGEN BIOSCIENCES CO., LTD. Inventor TIAN, Siyu
The present invention relates to the fields of biomedicine and virology, and in particular to a nucleic acid vaccine for preventing and/or treating mpox virus infections. In particular, provided in the present invention are a polypeptide or a polypeptide combination, a nucleic acid or a nucleic acid combination (in particular an mRNA or an mRNA combination), a composition, a pharmaceutical composition, a kit and the use thereof for preventing and/or treating mpox virus infections. Further provided in the present invention are an expression vector containing the nucleic acid or the nucleic acid combination and a host cell containing the nucleic acid or the nucleic acid combination or the expression vector.
4.WO/2025/141521LIPIDS HAVING DENDRITIC MOIETIES
WO - 03.07.2025
Int.Class A61K 39/145
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
39Medicinal preparations containing antigens or antibodies
12Viral antigens
145Orthomyxoviridae, e.g. influenza virus
 Appl.No PCT/IB2024/063236 Applicant SANOFI Inventor BAZIN, Emilie
Provided herein are dendritic lipids or pharmaceutically acceptable salts thereof. The dendritic lipids provided herein can be useful for delivery and expression of mRNA and encoded protein, e.g., as a component of liposomal delivery vehicle, and accordingly can be useful for treating various diseases, disorders and conditions, such as those associated with deficiency of one or more proteins.
5.WO/2025/144717COMPOSITIONS AND METHODS FOR INDUCING IMMUNE RESPONSE AGAINST EPSTEIN-BARR VIRUSES
WO - 03.07.2025
Int.Class A61K 39/245
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
39Medicinal preparations containing antigens or antibodies
12Viral antigens
245Herpetoviridae, e.g. herpes simplex virus
 Appl.No PCT/US2024/061315 Applicant REPLICATE BIOSCIENCE, INC. Inventor ALIAHMAD, Parinaz
The present disclosure relates to nucleic acids molecules, e.g., self-replicating RNA (srRNA) expressing antigenic determinant(s) derived from Epstein-Barr virus (EBV), recombinant cells and pharmaceutical compositions containing the same, as well as the use of such srRNA molecules, recombinant cells, and compositions for eliciting a pharmacodynamic effect in a subject. Also provided are methods for preventing and/or treating various health conditions associated with EBV infection.
6.WO/2025/139352DABIE BANDAVIRUS MRNA VACCINE AND PREPARATION METHOD THEREFOR
WO - 03.07.2025
Int.Class A61K 39/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
39Medicinal preparations containing antigens or antibodies
12Viral antigens
 Appl.No PCT/CN2024/128947 Applicant NANJING MEDICAL UNIVERSITY Inventor LIU, Xinjian
Provided are a Dabie bandavirus mRNA vaccine and a preparation method therefor. Specifically an optimized mRNA molecule is provided, and is cloned into a pGEM-3Zf(+)mRNA vaccine vector; the plasmid is linearized by means of enzyme digestion, and subjected to capping and poly(A) tail addition by means of an in-vitro transcriptase method to prepare an mRNA; the obtained mRNA is transfected into eukaryotic cells, and it is verified by means of an immunoblotting experiment that the mRNA can be expressed in vitro; and the mRNA is encapsulated by a lipid nanoparticle delivery system to obtain the mRNA vaccine, which, after immunizing mice, can induce the generation of a relatively high antibody level in serum. A viral neutralization test further proves that the immune serum can bind to viruses to prevent the viruses from infecting cells.
7.WO/2025/138665NATURAL ATTENUATED STRAIN OF INFECTIOUS LARYNGOTRACHEITIS VIRUS WITH GOOD SAFETY AND GOOD IMMUNOGENICITY AND USE
WO - 03.07.2025
Int.Class C12N 7/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
7Viruses, e.g. bacteriophages; Compositions thereof; Preparation or purification thereof
 Appl.No PCT/CN2024/102158 Applicant INSTITUTE OF ANIMAL HUSBANDRY AND VETERINARY MEDICINE, FUJIAN ACADEMY OF AGRICULTURAL SCIENCES Inventor HOU, Bo
A natural attenuated strain of infectious laryngotracheitis virus with good safety and good immunogenicity. The natural attenuated strain is named infectious laryngotracheitis virus ILTV FJ19, and has been deposited in the China Center for Type Culture Collection on November 29, 2023, with the deposit number of CCTCC NO: V2023109, and the deposit address of No. 299, Bayi Road, Wuchang District, Wuhan City, Hubei Province. Experiments show that the avian infectious laryngotracheitis virus ILTV FJ19 strain has stable passage ability, can adapt to inoculation via the allantoic cavity route, has very good safety and immunogenicity when inoculated in 14-day-old SPF chickens, can be used for eye-drop inoculation or oral inoculation, and can be used as a candidate strain of a live attenuated vaccine against ILTV.
8.WO/2025/144636ENGINEERED hMPV F PROTEIN IMMUNOGENS AND RELATED VACCINES
WO - 03.07.2025
Int.Class A61K 39/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
39Medicinal preparations containing antigens or antibodies
12Viral antigens
 Appl.No PCT/US2024/060449 Applicant THE SCRIPPS RESEARCH INSTITUTE Inventor HE, Linling
The present invention provides engineered human metapneumovirus (hMPV) F protein trimer immunogens. These engineered proteins are stabilized via specific modifications introduced into both the F2 subunit and the F1 subunit of a wildtype hMPV soluble F sequence, e.g., shortened F2 subunit C -terminus and interprotomer disulfide bond in the F1 subunit. Also provided in the invention are nanoparticle vaccines that contain the engineered hMPV soluble F immunogens displayed on self-assembling nanoparticles. The invention also provides methods of using such vaccine compositions in various therapeutic applications, e.g., for preventing or treating hMPV infections.
9.WO/2025/144801VACCINES FOR THE TREATMENT AND PREVENTION OF INFECTIOUS DISEASES IN INVERTEBRATES
WO - 03.07.2025
Int.Class A61K 39/125
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
39Medicinal preparations containing antigens or antibodies
12Viral antigens
125Picornaviridae, e.g. calicivirus
 Appl.No PCT/US2024/061728 Applicant DALAN ANIMAL HEALTH, INC. Inventor WEINBERG, Isaac
The disclosure provides compositions and methods for treating and vaccinating invertebrates and invertebrate populations from diseases.
10.2636832Uses, methods, polypeptides and polynucleotides
GB - 02.07.2025
Int.Class A61K 39/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
39Medicinal preparations containing antigens or antibodies
12Viral antigens
 Appl.No 202319922 Applicant UNIV TARTU Inventor ALAR AINTS
Polypeptides comprising bacteriophage polypeptides for use in preventing or treating autoimmune diseases, for example type 1 diabetes. Polypeptides comprising fragments or variants of bacteriophage polypeptides may also be used for this purpose. Nucleic acid molecules encoding such polypeptides may also be used for this purpose. The present invention also relates to vaccine compositions comprising such a polypeptide or comprising a nucleic acid molecule encoding such a polypeptide. Certain isolated peptides comprising fragments of bacteriophage polypeptides also form part of the present invention. The present invention also relates to methods of screening for an autoimmune disease by determining the level, in a body fluid sample obtained from a subject, of an antibody that binds to a bacteriophage polypeptide or fragment or variant thereof.
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