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IC:A61K31/00

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Analysis

1 / 80,055
1.3031785TRIAMTERENE OR NOLATREXED FOR USE IN THE TREATMENT OF PHENYLKETONURIA
ES - 11.07.2025
Int.Class A61K 45/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
45Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
 Appl.No 20704533 Applicant Som Innovation Biotech, S.A. Inventor INSA BORONAT, Raúl
2.3031815ANTIMICROBIAL COMPOSITIONS CONTAINING POLYQUATERNIUM
ES - 11.07.2025
Int.Class A01N 33/12
AHUMAN NECESSITIES
01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF ; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES ; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
33Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
02Amines; Quaternary ammonium compounds
12Quaternary ammonium compounds
 Appl.No 17712578 Applicant Kenvue Brands LLC Inventor BAI, Mingqi
3.20250221948Complex of 3-hydroxybutyric acid and sodium 3-hydroxybutyrate and preparation method thereof
US - 10.07.2025
Int.Class A61K 31/19
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
31Medicinal preparations containing organic active ingredients
185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
19Carboxylic acids, e.g. valproic acid
 Appl.No 19089543 Applicant NANJING NUTRABUILDING BIO-TECH CO., LTD. Inventor Liang RONG

The invention discloses a complex of 3-hydroxybutyric acid and sodium 3-hydroxybutyrate and a preparation method thereof. The complex provided by the invention effectively solves the acid/salt load and gastrointestinal side effects associated with the existing products, has good taste comfort, and has a good ketogenic effect, and can be better used as a dietary or nutritional supplement.

4.20250221954METHODS TO TREAT, PREVENT, OR REDUCE HYPERAMMONEMIA
US - 10.07.2025
Int.Class A61K 31/222
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
31Medicinal preparations containing organic active ingredients
21Esters, e.g. nitroglycerine, selenocyanates
215of carboxylic acids
22of acyclic acids, e.g. pravastatin
222with compounds having aromatic groups, e.g. dipivefrine, ibopamine
 Appl.No 18978528 Applicant Darren Alexander Rubin Inventor Darren Alexander Rubin

Methods, formulations, and applications of treating and preventing hyperammonemia by reducing ammonia levels are provided, which also have implications for reducing hemodialysis.

5.20250223381An Auricularia Auricula Polysaccharide, Its Application And Preparation Method Thereof
US - 10.07.2025
Int.Class C08B 37/00
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
BPOLYSACCHARIDES; DERIVATIVES THEREOF
37Preparation of polysaccharides not provided for in groups C08B1/-C08B35/110; Derivatives thereof
 Appl.No 18015393 Applicant BEIJING BEIQING BOYU INFORMATION TECHNOLOGY RESEARCH CO. LTD Inventor Sun Sun Chan

The invention provides an Auricularia auricula polysaccharide, its application and preparation method thereof, which belong to the technical field of improving polysaccharide. After being degreased, the Auricularia auricula is subjected to preliminary enzymolysis under the effect of helicase, is further subjected to deep enzymolysis under the effect of complex enzyme through synergetic ultrasound-assisted degradation and extraction with H2O2, and is subjected to mixed fermentation by Lactobacillus bulgaricus, Streptococcus thermophilus and Bifidobacterium longum, the obtained fermented Auricularia auricula polysaccharide is subjected to a phosphorylation reaction under the effect of a phosphorylation reagent, and after further deproteinization and decolorization, the obtained fermented Auricularia auricula polysaccharide is chelated with zinc salt to obtain a polysaccharide-zinc compound, and the amount of the extracted Auricularia auricula polysaccharide is improved. The finished product of the invention has the effects of reducing blood sugar and blood fat, regulating total cholesterol and effectively improving HDL cholesterol.

6.WO/2025/146415IMPROVEMENT IN ATHEROSCLEROTIC PLAQUE CHARACTERISTICS WITH OBICETRAPIB
WO - 10.07.2025
Int.Class A61K 31/397
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
397having four-membered rings, e.g. azetidine
 Appl.No PCT/EP2024/088467 Applicant NEWAMSTERDAM PHARMA B.V. Inventor KASTELEIN, Johannes Jacob Pieter
Methods are presented for improving atherosclerotic plaque characteristics in a patient with atherosclerotic cardiovascular disease (ASCVD). The method comprises administering an effective amount of obicetrapib, or pharmaceutically acceptable salt, solvate, or co-crystal thereof, and optionally co-administering an effective amount of ezetimibe, or pharmaceutically acceptable salt or solvate thereof, to the patient. Methods are also provided for reducing coronary artery inflammation in a patient with atherosclerotic cardiovascular disease (ASCVD). The method comprises administering an effective amount of obicetrapib, or pharmaceutically acceptable salt, solvate, or co-crystal thereof, and optionally co-administering an effective amount of ezetimibe, or pharmaceutically acceptable salt of solvate thereof, to the patient. In preferred embodiments, obicetrapib is administered as amorphous obicetrapib hemicalcium. In particularly preferred embodiments, amorphous obicetrapib hemicalcium and ezetimibe are administered daily in a fixed dose combination (FDC) oral dosage form.
7.WO/2025/147600AMINO QUINOLINE COMPOUNDS AND USES THEREOF
WO - 10.07.2025
Int.Class A61K 31/13
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
31Medicinal preparations containing organic active ingredients
13Amines, e.g. amantadine
 Appl.No PCT/US2025/010223 Applicant DEWPOINT THERAPEUTICS, INC. Inventor RIGUET, Eric
Provided herein are compounds of formula (I) or a stereoisomer or tautomer thereof, or a pharmaceutically acceptable salt, hydrate, or solvate of any of the foregoing, wherein R1, R2, n, L, R4, R5, R6, R7, and R8 are as defined elsewhere herein. Also provided are methods of preparing compounds of formula (I). Also provided herein are methods of modulating TDP-43 and methods of treating a disease or condition mediated by TDP-43 in an individual in need thereof.
8.WO/2025/147555REC-4881 (TAK-733) FOR USE IN TREATING OR PREVENTING COLORECTAL CANCER AND RELATED DISEASES
WO - 10.07.2025
Int.Class A61K 31/4184
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
41having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
41641,3-Diazoles
4184condensed with carbocyclic rings, e.g. benzimidazoles
 Appl.No PCT/US2025/010152 Applicant RECURSION PHARMACEUTICALS, INC. Inventor TOUTOUNCHIAN, Jordan
Methods are provided for treating or preventing colorectal cancer, related diseases, or symptoms of any of the foregoing, e.g., familial adenomatous polyposis (FAP), in subjects of 55 years or older. The methods include administering 3-[(2R)-2,3-dihydroxypropyl]-6-fluoro-5-(2-fluoro-4-iodoanilino)-8-methylpyrido[2,3-d]pyrimidine-4, 7-dione or a pharmaceutically acceptable salt thereof.
9.WO/2025/145965PYRROLE SULFONAMIDE ANTACID CRYSTAL AND PREPARATION METHOD THEREFOR AND USE THEREOF, AND PHARMACEUTICAL COMPOSITION
WO - 10.07.2025
Int.Class C07D 401/12
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
401Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
02containing two hetero rings
12linked by a chain containing hetero atoms as chain links
 Appl.No PCT/CN2024/142891 Applicant ZHEJIANG MEDICINE CO., LTD XINCHANG PHARMACEUTICAL FACTORY Inventor LI, Nanxing
The present invention relates to a pyrrole sulfonamide antacid crystal and a preparation method therefor and the use thereof, and a pharmaceutical composition. Specifically, disclosed in the present invention is a pyrrole sulfonamide antacid crystal of a compound of formula (I), and the chemical structural formula of the crystal is as represented by formula (I), wherein n=0.1 to 2.0. The crystal form has good stability, fluidity and humidity resistance; and the preparation method for the crystal form involves a simple process, is easy to control and is suitable for large-scale production.
10.WO/2025/145725UNSATURATED OLEFIN ALDEHYDE COMPOUND HAVING ANTI-INFLAMMATORY AND PHLEGM-ELIMINATING ACTIVITY, AND PREPARATION METHOD THEREFOR AND USE THEREOF
WO - 10.07.2025
Int.Class C07D 309/30
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
309Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
16having one double bond between ring members or between a ring member and a non-ring member
28with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
30Oxygen atoms, e.g. delta-lactones
 Appl.No PCT/CN2024/125019 Applicant INSTITUTE OF ZOOLOGY, GUANGDONG ACADEMY OF SCIENCES Inventor LONG, Hailin
Disclosed in the present invention are an unsaturated olefin aldehyde compound having an anti-inflammatory and phlegm-eliminating activity, and a preparation method therefor and the use thereof. An unsaturated olefin aldehyde compound as represented by formula I, or a pharmaceutically acceptable salt thereof, or a solvate thereof, wherein R1, R2, R3, R4 and R5 are independently selected from methyl or hydroxyl. The intestinal endophyte strain of Hepiaua larva of the present invention can be fermented to produce a new compound which has a stable performance, a low cytotoxicity and a significant anti-inflammatory and phlegm-eliminating activity.
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