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IC:A61B AND EN_ALLTXT:(coronavirus OR coronaviruses OR coronaviridae OR coronavirinae OR orthocoronavirus OR orthocoronaviruses OR orthocoronaviridae OR orthocoronavirinae OR betacoronavirus OR betacoronaviruses OR betacoronaviridae OR betacoronavirinae OR sarbecovirus OR sarbecoviruses OR sarbecoviridae OR sarbecovirinae OR "severe acute respiratory syndrome" OR sars OR "2019 ncov" OR covid)

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Analysis

1 / 346
1.WO/2021/247682METHODS FOR MITIGATING OR DIMINISHING SPREAD OF PATHOGENIC INFECTIONS
WO - 09.12.2021
Int.Class G16H 50/80
GPHYSICS
16INFORMATION AND COMMUNICATION TECHNOLOGY SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
50ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
80for detecting, monitoring or modelling epidemics or pandemics, e.g. flu
 Appl.No PCT/US2021/035421 Applicant ROSS, Peter M. Inventor ROSS, Peter M.
The present methods comprise initial administration of a first rapid test, such as rapid antigen test, that has a low likelihood of false positive results and a known likelihood of false negative results, alone or in conjunction with other rapid tests, to identify a first subpopulation of positives, to which an infection mitigation protocol (such as quarantine or the administration of a therapeutic treatment) is administered. Negatives are recorded and provisionally released from further study. A diagnostic test is then administered to this subpopulation, to identify the portion of this first subpopulation that were false positives in the first test. Ideally, a positive result for the diagnostic test is pathognomonic for the infection. Any infection mitigation protocol (such as quarantine) may then be discontinued for those testing negative in the first population and intensified for those testing positive, such as with contact tracing or other protocols, to identify all true positives and those they may have infected within the population.
2.WO/2023/144291REAL-TIME BREATH ANTIGEN DETECTION SYSTEM AND METHOD THEREOF
WO - 03.08.2023
Int.Class A61B 5/08
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes ; Identification of persons
08Measuring devices for evaluating the respiratory organs
 Appl.No PCT/EP2023/051983 Applicant CHARITÉ - UNIVERSITÄTSMEDIZIN BERLIN Inventor BIEREWIRTZ, Tim
The invention relates to a system for antigen detection comprising a first container configured to collect aerosols out of exhaled air of a human and a second container suitable for a solvent, wherein nanoparticles are dissolved in the solvent and the nanoparticles are linked to antibodies, further wherein a change of optical properties of the solvent is detectable upon contact between the antibodies and matching antigens. Here, a person can exhale air into the first container, and the aerosols exhaled in the air stick in a filter on one side of the first container. Thereupon, the first container is incooperable in the second container, in which a solvent with nanoparticles dissolved therein and antibodies coupled thereto are located. The incooperability, in particular a shuttling stroke motion, flushes the aerosols into the solvent. If antigens matching the antibodies are present on the aerosols, the nanoparticles agglomerate around the antigen, changing the optical properties of the solvent, which is irradiated by a light source and detectable by a light sensor. In further aspects, the invention relates to a method using the system according to the invention. The invention further relates to corresponding medical uses and therapeutic methods of administering a prevention of a medical condition associated with a SARS Coronavirus, in addition to diagnostic uses and methods.
3.WO/2022/015731ANTERIOR NARES SWAB AND USES THEREOF
WO - 20.01.2022
Int.Class A61J 1/05
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
1Containers specially adapted for medical or pharmaceutical purposes
05for collecting, storing or administering blood, plasma or medical fluids
 Appl.No PCT/US2021/041429 Applicant PRESIDENT AND FELLOWS OF HARVARD COLLEGE Inventor SPRINGER, Michael
The technology described herein is directed to an anterior nares swab that is automation compatible. In one aspect, the swab comprises a cap, a threaded portion, a neck, and a sample collection head. The cap can be integrally and/or monolithically formed with any one or more of the threaded portion, the neck, and the sample collection head; or can be removably coupled to any one or more of the threaded portion, the neck, and the sample collection head. In additional aspects, described herein are kits comprising said swabs and methods of using said swabs.
4.20230165571SAMPLE COLLECTION SWAB
US - 01.06.2023
Int.Class A61B 10/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
10Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
 Appl.No 17922518 Applicant PRESIDENT AND FELLOWS OF HARVARD COLLEGE Inventor Richard NOVAK

The technology described herein is directed to a swab for sample collection. In one aspect, the swab comprises a sample collection head, which comprises a plurality of spaced annular rings. In one embodiment, the swab further comprises a tapered neck and a handle. In one embodiment, the swab is injection-molded using polypropylene. In other aspects, described herein are swabs comprising a water-soluble or biodegradable material. In additional aspects, described herein are kits comprising said swabs and methods of using said swabs.

5.WO/2022/159886BIOLOGICS DETECTION DEVICE
WO - 28.07.2022
Int.Class G06T 7/00
GPHYSICS
06COMPUTING; CALCULATING OR COUNTING
TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
7Image analysis
 Appl.No PCT/US2022/013690 Applicant ADVANCED MEDICAL SOLUTIONS INTERNATIONAL, LLC Inventor SAID, Nassar, O.
Methods and apparatus for non-invasively and accurately detecting a chemically- stable molecular structure. The methods and apparatus can be used to detect molecules associated with disease and disorders, and objects or subjects associated with such disease and disorders, such as contaminated with the molecules or pathogens, or having disease or disorder associated with the molecules or pathogens.
6.WO/2022/013877METHOD AND SYSTEM FOR PREPARING A SAMPLE FOR DETECTION OF PROTEINS
WO - 20.01.2022
Int.Class A61B 5/08
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes ; Identification of persons
08Measuring devices for evaluating the respiratory organs
 Appl.No PCT/IL2021/050869 Applicant BREATH OF HEALTH LTD. Inventor LAOR, Marsel Arie
The present invention provides a system including a pump configured to pump an air sample, from a container to a cooling chamber, at a capacity of at least 0.5 liter/sec, the cooling chamber is configured to cool the exhaled air sample to a sub-zero temperature, and is in fluid connection to a spectrometer test chamber; an inert gas source, configured to supply an inert gas to the test chamber at a pressure higher than the atmospheric pressure; and a heating unit for heating said air sample. Further provided is a method for preparing an air sample for detection of a mixture of proteins.
7.WO/2024/116103METHOD AND SYSTEM FOR DETECTING NON-VOLATILE AND SEMI-VOLATILE ORGANIC COMPOUNDS IN MID-IR SPECTROMETRY GAS CELL CONFIGURATIONS
WO - 06.06.2024
Int.Class G01N 1/38
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
1Sampling; Preparing specimens for investigation
28Preparing specimens for investigation
38Diluting, dispersing or mixing samples
 Appl.No PCT/IB2023/062047 Applicant BREATH OF HEALTH LTD. Inventor LAOR, Marsel Arie
The embodiments provide a system including a pump configured to pump an air sample, from a container to a cooling chamber, the cooling chamber configured to cool the exhaled air sample to a sub-zero temperature, and is in fluid communication with an injector unit. The injector unit mixes the cooled air sample and inert gas and injects the mixed air sample at a high velocity to a test chamber. Further provided is a method for preparing an air sample for detection of a mixture of proteins.
8.WO/2024/036192COMPOSITIONS AND METHODS FOR ASSESSING THE SEVERITY OF AND TREATING COVID-19
WO - 15.02.2024
Int.Class C12Q 1/6827
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
6813Hybridisation assays
6827for detection of mutation or polymorphism
 Appl.No PCT/US2023/071902 Applicant THE JOHNS HOPKINS UNIVERSITY Inventor JOHNS, Roger
The present invention relates to the field of virology. More specifically, the present invention provides compositions and methods for assessing the severity of and treating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or COVID-19. In particular embodiments, a method for treating COVID-19 in a patient comprises the step of administering to the patient an isolated, recombinant antibody or antigen-binding fragment thereof that binds human Resistin.
9.20240277252MULTIPLEXED ANTIGEN-BASED DETECTION OF SARS-COV-2 AND OTHER DISEASES USING NANOMECHANICAL SENSORS
US - 22.08.2024
Int.Class A61B 5/08
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes ; Identification of persons
08Measuring devices for evaluating the respiratory organs
 Appl.No 18572345 Applicant Northwestern University Inventor Vinayak P. Dravid

Nanomechanical sensors comprising an antibody-functionalized microcantilever and methods of using the same are described herein.

10.WO/2021/243372CLOSED-LOOP ANTIMICROBIAL PHOTO-PLASMAPHERESIS
WO - 02.12.2021
Int.Class A61M 1/36
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
1Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
 Appl.No PCT/US2021/070633 Applicant BAYLOR COLLEGE OF MEDICINE Inventor SZIGETI, Reka
The present disclosure concerns systems and methods related to the treatment, prevention, delay of onset, or reduction of severity of a microbial infection in an individual, including closed-loop plasmapheresis and extracorporeal light irradiation of the plasma of the individual. The systems and methods further relate to irradiation of the plasma of the individual with UV and/or visible light, optionally in the presence of a photosensitizer. The systems and methods further relate to light irradiation inactivation of microbial particles in the plasma taken from the individual. The systems and methods further relate to the optional filtration of microbial particles from UV light-treated plasma. The systems and methods further relate to reinfusion of the UV light-treated, optionally filtered, plasma back into the individual. The systems and methods further relate to treating, preventing, delaying onset of, or reducing in severity a viral infection, particularly a viral infection caused by a Coronaviridae family virus, at least including SARS-CoV-2. The systems and methods are further configured to reduce viral load and/or lymphocyte reinfection rate in the individual.
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