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Analysis

1.WO/2021/207293SCALABLE BIOREACTOR SYSTEMS AND RELATED METHODS OF USE
WO 14.10.2021
Int.Class C12M 3/04
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
3Tissue, human, animal or plant cell, or virus culture apparatus
04with means providing thin layers
Appl.No PCT/US2021/026071 Applicant MISSION BARNS, INC. Inventor ENGELMAYR, George C. Jr.
Bioreactors configured to scale-up the production of greater quantities of cells at relatively low cost are provided. These bioreactors may be utilized in the production of large-scale quantities of cell-based meat and cell-based fat. The bioreactors may be reusable and may have a high surface area-to-volume ratio for adherent cell expansion. The bioreactors may be capable of yielding a large number of adherent cells per bioreactor unit.
2.WO/2021/207668PORTABLE MEDICAL OBSERVATION AND ISOLATION UNIT
WO 14.10.2021
Int.Class F24F 3/16
FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
24HEATING; RANGES; VENTILATING
FAIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
3Air-conditioning systems in which conditioned primary air is supplied from one or more central stations to distributing units in the rooms or spaces where it may receive secondary treatment; Apparatus specially designed for such systems
12characterised by the treatment of the air otherwise than by heating and cooling
16by purification, e.g. by filtering; by sterilisation; by ozonisation
Appl.No PCT/US2021/026673 Applicant AMERICAN HEALTH DEVELOPMENT, LLC Inventor HEATH, III, Miller Lee
Provided herein are modular container units and assemblies for treating patients and personal protection. Further provided herein are warehouses and factories for storing the container units and assemblies, vehicles and methods for transporting the container units and assemblies, methods of treating patients with the container units and assemblies, and kits for sanitizing and assembling the container units and assemblies.
3.WO/2021/207693MOBILE LAB-ON-A-CHIP DIAGNOSTIC SYSTEM
WO 14.10.2021
Int.Class G01N 27/26
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
27Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
26by investigating electrochemical variables; by using electrolysis or electrophoresis
Appl.No PCT/US2021/026708 Applicant MCINTOSH, Sean Inventor MCINTOSH, Sean
A testing system for conducting electrochemistry analysis of a specimen sample is provided. The testing system includes a testing receptacle device (12) and a diagnostic device. The testing receptacle device includes a receptacle (22) having an interior space (30) defined therein and a lid (24) configured to be secured on an upper end of the receptacle. The lid includes an opening (50) extending into the receptacle and a cartridge slot (54) for receiving a test sensor cartridge having a functionalized electrode strip with an electrode well contact point provided thereon. The diagnostic device is configured as a potentiostat or similar device and includes a docking port for receiving a lower end of the testing receptacle device. The testing system is configured for receiving a specimen sample through the opening in the receptacle lid and placing the specimen sample in contact with the electrode well contact point of the functionalized electrode strip.
4.20210317396THREE-DIMENSIONAL BIOREACTOR FOR VIRAL VECTOR PRODUCTION
US 14.10.2021
Int.Class C12M 1/12
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
12with sterilisation, filtration, or dialysis means
Appl.No 17301625 Applicant SOUTHWEST RESEARCH INSTITUTE Inventor Jian LING

The present disclosure relates to the design, fabrication, and applications of a three-dimensional (3D) bioreactor for expansion of viral vector producing cells and ultimate harvesting of viral vectors. The bioreactor is composed of non-random interconnected voids providing a continuous three-dimensional surface area for cell adherence and growth.

5.WO/2021/204095METHOD AND EQUIPMENT OF PHENETHYLAMINE PRODUCTION
WO 14.10.2021
Int.Class C12M 1/40
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
40Apparatus specially designed for the use of free, immobilised, or carrier-bound enzymes, e.g. apparatus containing a fluidised bed of immobilised enzymes
Appl.No PCT/CN2021/085499 Applicant ENZYMASTER (NINGBO) BIO-ENGINEERING CO., LTD. Inventor YANG, Zhuhong
Provided is a production equipment of phenethylamine, comprising a first reaction device (1); a second reaction device (2), wherein the second reaction device (2) is connected to the first reaction device (1); and a circulation device (4), the circulation device (4) is respectively connected to the first reaction device (1) and the second reaction device (2); an acetone storage device (5); a centrifugal extraction device (6); a phenethylamine processing device; a phenethylamine storage device (10); wherein the first reaction device (1) and the second reaction device (2) have the same structure. Also provided is a production method of phenethylamine, which uses transaminase as a catalyst, so that acetophenone and isopropylamine can flow through the transaminase to complete the reaction, the reaction is completed in one step, the production cycle is shortened, and the production cost is reduced.
6.WO/2021/206555FLUIDIC DEVICE, CELL CULTURING SYSTEM AND METHOD OF TESTING A COMPOUND
WO 14.10.2021
Int.Class B01L 3/00
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
3Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
Appl.No PCT/NL2021/050231 Applicant UNIVERSITEIT TWENTE Inventor DE SÁ VIVAS, Aisen Gabriel
A fluidic device, in particular a microfluidic chip, for culturing a 3D cell culture comprises a bottom wall defining a bottom side of an open-top chamber arranged for containing a cell culture medium. A fluidic channel extends below the chamber between a channel inlet and a channel outlet for guiding a fluid flow. The bottom wall is provided with a micro-opening through which the chamber and the microfluidic channel are in fluid communication. A side wall extends from the bottom wall circumferentially around the chamber to a top wall opposite the bottom wall. An upper edge of the side wall delimits an open access upper side of the chamber and the top wall is arranged for closing the chamber at the upper side thereof and to be supported by the upper edge of the side wall. A sealing means is provided between opposing surfaces of the upper edge of the side wall and the top wall and arranged for reversible fluid sealing of the side wall and top wall when the chamber is closed at the upper side by the top wall.
7.20210317278MODIFIED POLYMER FILM SURFACES FOR SINGLE-USE BIOREACTOR BAGS AND BIOCONTAINMENT AND METHODS OF FORMING SAME
US 14.10.2021
Int.Class C08J 7/12
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H142
7Chemical treatment or coating of shaped articles made of macromolecular substances
12Chemical modification
Appl.No 17226718 Applicant THE SECANT GROUP, LLC Inventor Peter D. GABRIELE

In some embodiments, a polymer film includes a base composition of poly(ethylene-vinyl acetate) and a surface composition comprising hydroxy groups. In some embodiments, a polymer film includes a base layer of a first composition of poly(ethylene-vinyl acetate), a surface layer at a surface of the base layer, and a coating layer of a second composition of a copolymer of glycerol and sebacic acid. The surface layer includes surface hydroxy groups converted from acetate groups of the poly(ethylene-vinyl acetate). The second composition is attached to the surface layer by ester bonds between carboxyl groups of the copolymer and the hydroxy groups. A single-use bioreactor bag includes a polymer film including a base composition of poly(ethylene-vinyl acetate) and a surface composition comprising hydroxy groups. A method of modifying a poly(ethylene-vinyl acetate) film includes converting acetate groups at a first surface of the poly(ethylene-vinyl acetate) film to hydroxy groups.

8.20210317397Device for High Throughput Isolation and Cultivation of Microbial Species
US 14.10.2021
Int.Class C12M 1/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
Appl.No 17228528 Applicant Northeastern University Inventor Slava EPSTEIN

High capacity, low cost devices for use in growing monocultures of novel, previously unknown microbial species contain adhesive layers with wells covered by nanoporous membranes. The devices are placed in natural environments for cultivation of unknown microbial species.

9.20210317503BACTERIUM NUMBER MEASURING METHOD AND BACTERIUM NUMBER MEASURING SYSTEM
US 14.10.2021
Int.Class C12Q 1/18
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
02involving viable microorganisms
18Testing for antimicrobial activity of a material
Appl.No 17224957 Applicant HITACHI, LTD. Inventor Shunsuke KAWABE

Provided is a bacterium number measuring system comprising a database storing known bacterial growth patterns in advance and an analyzing part. The analyzing part has first cultures containing a bacterial liquid that contains a measurement target bacteria and second cultures being different from the first cultures and containing the bacterial liquid and an antimicrobial drug. The analyzing part performs bacterium number measurement which measures the number of bacteria in the first cultures on a culturing part where culturing has started in the first and second cultures. The analyzing part compares the bacterium number measurement result with the growth curves stored in the database and thereby determines a timing to perform MIC measurement which measures the number of bacteria in the second cultures to determine a minimum inhibitory concentration of the measurement target bacterium. The analyzing part performs the MIC measurement at the thus-determined timing.

10.WO/2021/206752SYSTEM AND METHOD FOR SENSING, CAPTURE AND RELEASE OF BIOMOLECULES OR CELLS
WO 14.10.2021
Int.Class C12M 1/34
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
34Measuring or testing with condition measuring or sensing means, e.g. colony counters
Appl.No PCT/US2020/055931 Applicant INDIANA BIOSCIENCES RESEARCH INSTITUTE, INC. Inventor PUGIA, Michael, J.
Collection of target analytes from complex samples is performed in detection microwell which includes a size exclusion filter and allows incubating the target analyte with affinity agents for a target analyte for capture and removal of non-target molecules. Detection of the target analytes by collection of the complexes in close proximity to a working electrode and a reference electrode facilitates the detection electrochemical labels produced.