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Analysis

1.20210315838SYSTEMS, METHODS, AND KITS FOR DIAGNOSTICS AND TREATMENT OF VIRAL RESPIRATORY INFECTION
US 14.10.2021
Int.Class A61K 31/05
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
05Phenols
Appl.No 17301188 Applicant Applied Biology, Inc. Inventor Ofer A. Goren

The present disclosure includes methods, systems, kits and compositions for treating, preventing and diagnosing viral infections, specifically SARS-CoV-2 infections, with an anti-androgen and anti-thyroid medication, a thyroid receptor antagonist, a TGF-β inhibitor or a combination thereof. The present disclosure also describes methods and compositions for the treatment of viral respiratory diseases, specifically SARS-CoV-2 infections, including anti-androgens, anti-thyroid medications, thyroid receptor antagonists, TGF-β inhibitors, RXR inhibitors, furin inhibitors or other agents to disrupt the androgen signaling.

2.WO/2021/203933TRADITIONAL CHINESE MEDICINE FOR DISPERSING LUNG QI AND DETOXICATION
WO 14.10.2021
Int.Class A61K 36/8994
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
88Liliopsida (monocotyledons)
899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
8994Coix (Job's tears)
Appl.No PCT/CN2021/081339 Applicant SHANDONG BUCHANG PHARMACEUTICALS CO., LTD. Inventor ZHANG, Boli
A traditional Chinese medicine for dispersing lung qi and detoxication, a preparation method therefor, use thereof, and an analysis method. This traditional Chinese medicine contains a traditional Chinese medicine active extract. The active extract is composed of a first extract and a second extract, wherein the first extract is a water extract or alcohol-water extract of ephedra, bitter apricot seed, raw gypsum, coix seed, rhizome of swordlike atractylodes, patchouli, polygonum cuspidatum, verbena, reed rhizome, lepidium seed, pummelo peel, and artemisia annua, the second extract is a water extract or an alcohol-water extract of licorice, and the first extract and the second extract are separately obtained. This traditional Chinese medicine can be used for treating coronavirus diseases, such as novel coronavirus pneumonia.
3.WO/2021/205403ENDOXIFEN FOR THE TREATMENT OF BIPOLAR I DISORDER
WO 14.10.2021
Int.Class A61K 31/138
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
13Amines, e.g. amantadine
135having aromatic rings, e.g. methadone
138Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
Appl.No PCT/IB2021/052971 Applicant JINA PHARMACEUTICALS, INC. Inventor AHMAD, Ateeq
A method for managing or decreasing a risk of suicidal behaviour in a patient undergoing treatment of bipolar I disorder is provided. The said method includes maintaining the therapeutically effective concentration of endoxifen by administrating a dose of 2 mg to 16 mg of endoxifen citrate in an enteric coated tablet once per day for at least 21 days.
4.20210315931TREATMENT AND PREVENTION OF INJURY DUE TO RADIATION EXPOSURE
US 14.10.2021
Int.Class A61K 33/32
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
33Medicinal preparations containing inorganic active ingredients
24Heavy metals; Compounds thereof
32Manganese; Compounds thereof
Appl.No 17257940 Applicant MEDESIS PHARMA Inventor Elsa COMPTE

The disclosure relates to the treatment and/or prevention of radiation damage by administering a reverse micelle system.

5.WO/2021/205473STRUCTURALLY DEFINED, BETTER TOLERATED, ORALLY ADMINSTERED, PROCESSED ARSENOLITE, A PROCESS FOR ITS PREPARATION, A PHARMACEUTICAL COMPOSITION AND USES THEREOF
WO 14.10.2021
Int.Class A61K 33/36
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
33Medicinal preparations containing inorganic active ingredients
24Heavy metals; Compounds thereof
36Arsenic; Compounds thereof
Appl.No PCT/IN2021/050341 Applicant BENDALE, Yogesh Inventor BENDALE, Yogesh
The present invention is drawn to a surface functionalized nanoparticle of Tetra-arsenic Hexoxide by carbon- and carbon-based compounds, that are largely mono-dispersed and bi-pyramidal faceted, having presence of silicon, floats on water, storage stable, capable of oral administration for its effect against multiple chronic diseases including cancer.
6.20210315871METHODS FOR TREATING AORTIC VALVE STENOSIS WITH A HEDGEHOG PATHWAY INHIBITOR
US 14.10.2021
Int.Class A61K 31/4402
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
44Non-condensed pyridines; Hydrogenated derivatives thereof
4402only substituted in position 2, e.g. pheniramine, bisacodyl
Appl.No 17354648 Applicant The Trustees of Indiana University Inventor Jingwu Xie

Methods of treating a valvular heart disease are provided. Methods for treating valvular heard disease include administering to a subject a therapeutically effective amount of at least one hedgehog pathway inhibitor. Also provided are methods for reducing fibrosis in a subject, which comprise administering to the subject a therapeutically effective amount of at least one hedgehog pathway inhibitor.

7.WO/2021/203434NANO MATERIAL FOR OSTEOCLAST ACIDIC CLOSED REGION AND PREPARATION METHOD THEREFOR
WO 14.10.2021
Int.Class A61K 47/69
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
50the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
69the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
Appl.No PCT/CN2020/084300 Applicant SIR RUN RUN SHAW HOSPITAL ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE Inventor LIN, Xian Feng
Disclosed are a nano material for an osteoclast acidic closed region and a preparation method therefor. The nano material for an osteoclast acidic closed region comprises a nano material, bone-targeting molecules and a compound which causes an osteoclast acidic closed region to undergo a chemical reaction. After the nano material is subjected to bone targeting molecular modification, a compound which causes an osteoclast acidic region to undergo a chemical reaction is entrapped; and osteoclasts are inhibited by means of accurate mature osteoclast targeting and a biological cascade reaction regulated by a physiological chemical reaction. A new way of thinking and a new tool are provided for the pharmaceutical treatment of abnormal osteoclast activation.
8.WO/2021/203614PHARMACEUTICAL COMPOSITION FOR TREATMENT OF CORONAVIRUS DISEASES AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
WO 14.10.2021
Int.Class A61K 36/8994
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
88Liliopsida (monocotyledons)
899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
8994Coix (Job's tears)
Appl.No PCT/CN2020/112431 Applicant TIANJIN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE Inventor ZHANG, Boli
The present invention relates to a pharmaceutical composition for the treatment of coronavirus diseases, a preparation method therefor, and application thereof. The pharmaceutical composition contains a first Chinese herbal medicine extract and a second Chinese herbal medicine extract as active ingredients, the first Chinese medicinal extract being water or alcohol extracts of ephedra, bitter almond, raw gypsum, coix seed, atractylodes, patchouli, polygonum cuspidatum, verbena, reed root, lepidium seed, pummelo peel, and sweet wormwood, and the second Chinese herbal medicine extract being the water or alcohol extract of licorice. The pharmaceutical composition per ten grams contains not less than 2.3 mg of ephedrine hydrochloride and pseudoephedrine hydrochloride in total, not less than 42.7 mg of naringin, and not less than 7.7 mg of glycyrrhizic acid. The pharmaceutical composition of the present invention can be used for treatment of diseases caused by coronaviruses.
9.20210315929PRODUCTS AND METHODS FOR ORGAN PROTECTION WITH NOBLE NANOPARTICLES
US 14.10.2021
Int.Class A61K 33/242
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
33Medicinal preparations containing inorganic active ingredients
24Heavy metals; Compounds thereof
242Gold; Compounds thereof
Appl.No 16843114 Applicant UCHICAGO ARGONNE, LLC Inventor Elena A. Rozhkova

Products and methods for redirecting the pathological biochemical process of accumulation of reduced pyridine nucleotides under deleterious hypoxia conditions toward the reduction of the precursor salt and the biosynthesis of biologically compatible, antioxidant noble metal nanoparticles and the simultaneous restoring of the tissue redox state are provided. The products and methods have application in the treatment of hypoxia and hypoxia-related diseases and disorders. Such products and methods are also useful in organ transplantation and recovery, in screening of anti-hypoxia agents, and in detecting elevated levels of the reducing equivalents of the redox state, for example, NADH, NADPH, GSH, and TrxSH2, in cells, tissues, or organs.

10.20210315852DELIVERY METHODS FOR OMEGA-3'S AND COMPOSITIONS FOR VITAMINS AND MINERALS USED TO ENHANCE VISUAL ACUITY AND MENTAL DEVELOPMENT IN THE HUMAN BODY
US 14.10.2021
Int.Class A61K 31/202
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
19Carboxylic acids, e.g. valproic acid
20having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid
202having three or more double bonds, e.g. linolenic acid
Appl.No 17229693 Applicant Viva Life Science, Inc. Inventor Thuong Cao Do

The present invention relates to the delivery method of Omega-3's and nutritional supplements for the human diet used to aid mental and visual development of human embryos as well as enhance visual acuity and mental fitness in humans. The invention contains vitamins, minerals, and microencapsulated fish oil powder containing DHA and EPA.