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IC:C07K16/10

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Analysis

1 / 819
1.WO/2026/102432HUMAN ANTIBODIES TO MARBURG VIRUS AND METHODS OF USE THEREFOR
WO - 15.05.2026
Int.Class C07K 16/10
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
08against material from viruses
10from RNA viruses
 Appl.No PCT/US2025/054898 Applicant VANDERBILT UNIVERSITY Inventor CROWE, JR., James E.
The present disclosure is directed to antibodies binding to and neutralizing Marburg Virus and methods for use thereof.
2.WO/2026/098555USE OF ANTI-RSV ANTIBODY IN PREVENTION AND TREATMENT OF RSV
WO - 15.05.2026
Int.Class C07K 16/10
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
08against material from viruses
10from RNA viruses
 Appl.No PCT/CN2025/133017 Applicant ZHUHAI TRINOMAB PHARMACEUTICAL CO., LTD. Inventor DING, Jiyuan
Provided in the present invention are an anti-RSV antibody and the use of the anti-RSV antibody in the preparation of a drug for preventing or treating RSV infections or symptoms or diseases related thereto, wherein the RSV infections comprise subtype A and subtype B infections and upper respiratory tract RSV infections and/or lower respiratory tract RSV infections, and the symptoms or diseases related to RSV infections comprise fevers, coughs, sore throats, runny noses, and dyspnea, bronchitis or pneumonia caused by RSV infections.
3.WO/2026/098538NEUTRALIZING ANTIBODY AGAINST HUMAN PARAINFLUENZA VIRUS TYPE 3 AND USE THEREOF
WO - 15.05.2026
Int.Class C07K 16/10
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
08against material from viruses
10from RNA viruses
 Appl.No PCT/CN2025/132912 Applicant BEIJING WISDOMAB BIOTECHNOLOGY CO., LTD. Inventor FU, Xinlei
Provided are an antibody against human parainfluenza virus type 3, a bispecific antibody against human parainfluenza virus type 3 and respiratory syncytial virus, a nucleic acid molecule encoding the antibody and/or the bispecific antibody, a vector comprising the nucleic acid molecule, a host cell comprising the nucleic acid molecule or the vector, and a pharmaceutical composition comprising the antibody and/or the bispecific antibody. Also provided are a method for preparing and purifying the antibody and/or the bispecific antibody, and a use of the antibody and/or the bispecific antibody.
4.20260125435IL-10 VARIANT MOLECULES AND METHODS FOR TREATING INFLAMMATORY DISEASE AND ONCOLOGY
US - 07.05.2026
Int.Class A61P 29/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
29Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs
 Appl.No 19390302 Applicant Deka Biosciences, Inc. Inventor John MUMM

The application relates to compositions or formulations comprising variant IL-10 molecules, fusion proteins, and chimeric proteins thereof useful for the treatment of cancer, inflammatory diseases or disorders, and autoimmune diseases or disorders.

5.WO/2026/085715TRIVALENT INFLUENZA NANOPARTICLE VACCINE WITH BROAD-SPECTRUM EPITOPE AND USE THEREOF
WO - 30.04.2026
Int.Class C07K 19/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
19Hybrid peptides
 Appl.No PCT/CN2024/126475 Applicant CHENGDU NANOMICROGEN BIOTECH CO., LTD. Inventor PENG, Chun
The present invention belongs to the field of biomedicine. Provided are an influenza nanoparticle vaccine, and a preparation method therefor and the use thereof. A fusion protein containing an influenza virus strain HA protein or a fragment thereof, an antigenic epitope of the influenza virus protein, and ferritin, as an antigen, can induce an immune response effect against an influenza virus, and a vaccine composed of the fusion protein and an MF59 adjuvant can induce a protection effect against viral challenge and have a good cross-protection effect.
6.WO/2026/085146HIGHLY SCALABLE MULTIPLEX SEROLOGY BY MASS SPECTROMETRY ANALYSIS OF BEADS
WO - 23.04.2026
Int.Class G01N 33/50
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
 Appl.No PCT/US2025/050950 Applicant THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY Inventor CLAVE, Xavier, Rovira
The present disclosure provides methods for determining the presence of at least two biomolecules in a sample. The present disclosure further provides methods for determining the presence of a two or more biomolecules in a sample using single particle mass spectrometry as a readout.
7.2026512670抗原中の変異ホットスポットの予測
JP - 20.04.2026
Int.Class C07K 14/165
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
005from viruses
08RNA viruses
165Coronaviridae, e.g. avian infectious bronchitis virus
 Appl.No 2025524237 Applicant マックス－プランク－ゲゼルシャフト・ツア・フェルデルング・デア・ヴィッセンシャフテン・エー・ファオ Inventor ハマー，ゲルハルト
本発明は、抗原の部位特異的変異活性を予測するためのコンピュータ実装方法に関し、前記方法は、（ａ）前記抗原の少なくとも１つの三次元構造、好ましくは前記抗原の三次元構造のアンサンブルをインシリコで提供するステップと、（ｂ）前記抗原に結合可能または特異的な少なくとも１つの抗体またはそのフラグメントの少なくとも１つの三次元構造、好ましくは前記抗体またはそのフラグメントの三次元構造のアンサンブルをインシリコで提供するステップと、（ｃ）（ｂ）の構造に対する（ａ）の構造のアクセシビリティをインシリコで決定し、アクセシビリティが高いほど、特に前記抗体またはそのフラグメントによって及ぼされる選択圧の下で、変異活性が高いことを示すステップと、を含み、これにより、前記部位特異的変異活性を予測する。
【選択図】図１
8.121874135PRRS复制缺陷型疫苗PRRSV-△ORF5a株制备方法和应用
CN - 17.04.2026
Int.Class C12N 7/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
7Viruses, e.g. bacteriophages; Compositions thereof; Preparation or purification thereof
 Appl.No 202511827653.1 Applicant 中国农业科学院上海兽医研究所（中国动物卫生与流行病学中心上海分中心） Inventor 于海
本发明公开了一株猪繁殖与呼吸综合征（PRRS）复制缺陷型疫苗rPRRSV‑△ORF5a株制备方法和应用。本发明的PRRSV复制缺陷型疫苗rPRRSV‑△ORF5a株在稳定表达PRRSV ORF5a蛋白的Marc‑145细胞系正常复制且具有较高的病毒滴度，在普通Marc‑145细胞系只能进行一次性感染。经动物实验证明复制缺陷型病毒rPRRSV‑△ORF5a株可以抵抗同源强毒的感染，具有免疫保护效果。该疫苗株有望成为一种安全有效的新型PRRSV疫苗，有效解决PRRSV灭活疫苗不能诱导细胞免疫等缺点，同时解决PRRSV弱毒疫苗的安全性问题。
9.WO/2026/080438COMPOSITIONS AND METHODS FOR DETECTION TREATMENT, AND PREVENTION OF HIV INFECTION
WO - 16.04.2026
Int.Class C07K 14/005
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
005from viruses
 Appl.No PCT/US2025/049785 Applicant INTUITIVE BIOSCIENCES, INC. Inventor LUKE, Kimberly
The present disclosure relates to monoclonal antibodies specific for HIV. In particular, the disclosure relates to anti-Nef antibodies, and antigen-binding fragments thereof, as well as methods of detecting, treating, and preventing HIV infection.
10.WO/2026/076482NANOBODY CONJUGATES DIRECTED AGAINST NOROVIRUS
WO - 16.04.2026
Int.Class C07K 16/10
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
08against material from viruses
10from RNA viruses
 Appl.No PCT/AU2025/050163 Applicant GRIFFITH UNIVERSITY Inventor HANSMAN, Grant
The present disclosure generally relates to conjugates, such as fusion proteins of one or more single domain antibodies or nanobodies and one or more immunoglobulin Fc regions, compositions comprising the same and methods of using such conjugates and compositions for the diagnosis, prevention, amelioration and treatment of noroviral infections.
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