Feedback
Settings

Settings

Goto Application

60,911 results
Offices all Languages Stemming false Single Family Member true Include NPL false
RSS feed can only be generated if you have a WIPO account

Save query

A private query is only visible to you when you are logged-in and can not be used in RSS feeds

Query Tree

Refine Options

Offices
All
Specify the language of your search keywords
Stemming reduces inflected words to their stem or root form.
For example the words fishing, fished,fish, and fisher are reduced to the root word,fish,
so a search for fisher returns all the different variations
Returns only one member of a family of patents
Include Non-Patent literature in results

Full Query

IC:C07H21/00

Side-by-side view shortcuts

General
Go to Search input
CTRL + SHIFT +
Go to Results (selected record)
CTRL + SHIFT +
Go to Detail (selected tab)
CTRL + SHIFT +
Go to Next page
CTRL +
Go to Previous page
CTRL +
Results (First, do 'Go to Results')
Go to Next record / image
/
Go to Previous record / image
/
Scroll Up
Page Up
Scroll Down
Page Down
Scroll to Top
CTRL + Home
Scroll to Bottom
CTRL + End
Detail (First, do 'Go to Detail')
Go to Next tab
Go to Previous tab

Analysis

1 / 6,092
1.WO/2026/098610MODIFIED NUCLEOSIDE, SIRNA COMPRISING SAME, COMPOSITION, AND USE METHOD THEREFOR
WO - 15.05.2026
Int.Class C07H 19/10
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
19Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro derivatives thereof
02sharing nitrogen
04Heterocyclic radicals containing only nitrogen as ring hetero atom
06Pyrimidine radicals
10with the saccharide radical being esterified by phosphoric or polyphosphoric acids
 Appl.No PCT/CN2025/133302 Applicant INNOVENT BIOLOGICS (SUZHOU) CO., LTD. Inventor WANG, Yanhui
Provided are a modified nucleoside, a use and method for using the nucleoside to prepare an RNAi preparation for extrahepatic delivery, and an RNAi preparation for extrahepatic delivery obtained thereby. The RNAi preparation can effectively deliver RNAi to extrahepatic tissue, such as muscle tissue, like skeletal muscle tissue and myocardial tissue, and adipose tissue.
2.WO/2026/099473OLIGONUCLEOTIDES WITH NEW INTERNUCLEOSIDE LINKAGE
WO - 15.05.2026
Int.Class C07H 21/02
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
21Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
02with ribosyl as saccharide radical
 Appl.No PCT/EP2025/082436 Applicant VICO THERAPEUTICS B.V. Inventor FRANKEN, Dennis Christian
The current invention provides an improved oligonucleotide and its use for treating, ameliorating, preventing, delaying and/or treating a human genetic disorder, said oligonucleotide comprising an internucleoside linkage of the following formula (I).
3.WO/2026/101887NUCLEOTIDES WITH ALPHA-IMINO PHOSPHATE GROUPS AND BRIDGING SULFURS, AND METHODS OF SYNTHESIZING AND USING THE SAME
WO - 15.05.2026
Int.Class C07H 19/10
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
19Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro derivatives thereof
02sharing nitrogen
04Heterocyclic radicals containing only nitrogen as ring hetero atom
06Pyrimidine radicals
10with the saccharide radical being esterified by phosphoric or polyphosphoric acids
 Appl.No PCT/US2025/053934 Applicant ILLUMINA, INC. Inventor RICHARD, Jean-Alexandre
Nucleotides with alpha-imino phosphate groups and bridging sulfurs, and methods of synthesizing and using the same, are provided herein. In some examples, a nucleotide may include a sugar, a nucleobase coupled to the sugar, an alpha-imino phosphate group, and a bridging sulfur coupling the alpha-imino phosphate group to the sugar.
4.WO/2026/095005PRODUCTION OF OLIGONUCLEIC ACID
WO - 07.05.2026
Int.Class C07H 21/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
21Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
04with deoxyribosyl as saccharide radical
 Appl.No PCT/JP2025/038184 Applicant PEPTISTAR INC. Inventor TSUBAKI, Kota
The purpose of the present invention is to provide a method for efficiently producing an oligonucleic acid having a mixed P=O/P=S skeleton, with which it becomes possible to suppress the production of a PS-OP variant that is unexpectedly produced as a byproduct in the production of the oligonucleic acid having a mixed P=O/P=S skeleton.　The present invention relates to a method for producing an oligonucleic acid having a mixed P=O/P=S skeleton, the method being characterized in that an oxidation solution contains iodine, an organic solvent, and water and is additionally contains a trivalent phosphorus compound represented by the formula [wherein R1, R2, and R3 may be the same as or different from one another and each independently represent an optionally substituted C6-14 aryl or C1-6 alkyl group, wherein two R moieties may be bonded to each other and bonded to another adjacent atom to form a ring] at a concentration of 100-500 mM.
5.WO/2026/096896DEAMINASE VARIANTS WITH ALTERED SEQUENCE PREFERENCE
WO - 07.05.2026
Int.Class C12N 9/78
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
14Hydrolases (3.)
78acting on carbon to nitrogen bonds other than peptide bonds (3.5)
 Appl.No PCT/US2025/053524 Applicant WATCHMAKER GENOMICS, INC. Inventor KUDLOW, Brian
Provided herein are cytosine deaminase variants with enhanced preference for particular motifs, polynucleotides and vectors encoding the same, and methods of using the same.
6.WO/2026/093322IMPROVED DNA CONSTRUCTS FOR MANUFACTURING MESSENGER RNA BY IN VITRO TRANSCRIPTION
WO - 07.05.2026
Int.Class C12N 15/63
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
 Appl.No PCT/EP2025/081159 Applicant SANOFI PASTEUR INC. Inventor ALLOUCHE, Delphine
The present disclosure provides methods and compositions for improving the in vitro transcription (IVT) of messenger RNA (mRNA) using SP6, T7, or KP34 RNA polymerase. In particular, the present disclosure provides in vitro transcription templates with optimized nucleic acid sequences specific for use with SP6, T7, or KP34 RNA polymerase that improve mRNA transcript yield and/or reduce amounts of dsRNA.
7.WO/2026/096465METHODS AND SYSTEMS FOR IMMOBILIZING BIOMOLECULES AND USES OF SAME
WO - 07.05.2026
Int.Class B01J 19/24
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
19Chemical, physical or physico-chemical processes in general; Their relevant apparatus
24Stationary reactors without moving elements inside
 Appl.No PCT/US2025/052844 Applicant CORNELL UNIVERSITY Inventor LUO, Dan
A system includes one or more support(s) having a permeability of 2000 L m-2 h-1 bar-1 or more; and a hydrogel that includes one or more coupler reactive group(s) that connect with one or more linker reactive group(s) of one or more biomolecule(s). The hydrogel is disposed on the one or more support(s), and wherein the hydrogel has a permeability of 100 L m-2 h-1 bar-1 or more.
8.20260125413UNIVERSAL SOLID SUPPORTS AND PHOSPHORAMIDITE BUILDING BLOCKS FOR OLIGONUCLEOTIDE SYNTHESIS
US - 07.05.2026
Int.Class C07H 21/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
21Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
 Appl.No 19106597 Applicant AM CHEMICALS LLC Inventor Andrei Pavel Guzaev

Disclosed herein are chemical preparation of oligonucleotides, chemical entities useful in such preparation, processes for such preparation, and methods of use relating to the chemical preparation of oligonucleotides. Further disclosed herein are novel universal solid supports and phosphoramidite building blocks for oligonucleotide synthesis on solid phase that effect the removal of 3′-phosphate moieties during the course of oligonucleotide deprotection.

9.20260124249USE OF TNKS INHIBITORS FOR REGENERATION OF CARTILAGE
US - 07.05.2026
Int.Class A61K 35/28
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
 Appl.No 19439229 Applicant LIFLEX SCIENCE INC. Inventor Jin-Hong Kim

The present disclosure relates to a method of treating arthritis by targeting Tankyrase. The methods according to the present disclosure can be advantageously used for regeneration of cartilage tissue and for treating osteoarthritis by maximizing the matrix synthesis in cartilage by inhibition of Tankyrase and regulation of other proteins related therewith.

10.WO/2026/090505FLUOROPYRIMIDINE PARTICLES FOR THE TREATMENT OF CANCER
WO - 30.04.2026
Int.Class A61K 31/395
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
 Appl.No PCT/US2025/052417 Applicant WAKE FOREST UNIVERSITY HEALTH SCIENCES Inventor GMEINER, William Henry
A new class of multi-functional lipid nanoparticles comprising a fluoropyrimidine-based therapeutic and a combination of helper lipids is disclosed. The disclosed lipid nanoparticles are formulated for efficient delivery of therapeutic agents to target cells and can be used in the treatment of cancers, including colorectal cancer. The disclosed lipid nanoparticles exhibit improved cellular uptake and increased toxicity to cancerous cells compared to free- fluoropyrimidine therapeutic and other conventional therapeutics. A method for treating cancer by administering the disclosed lipid nanoparticles is also disclosed herein.
# -