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Analysis

1 / 12,601
1.WO/2026/098610MODIFIED NUCLEOSIDE, SIRNA COMPRISING SAME, COMPOSITION, AND USE METHOD THEREFOR
WO - 15.05.2026
Int.Class C07H 19/10
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
19Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro derivatives thereof
02sharing nitrogen
04Heterocyclic radicals containing only nitrogen as ring hetero atom
06Pyrimidine radicals
10with the saccharide radical being esterified by phosphoric or polyphosphoric acids
 Appl.No PCT/CN2025/133302 Applicant INNOVENT BIOLOGICS (SUZHOU) CO., LTD. Inventor WANG, Yanhui
Provided are a modified nucleoside, a use and method for using the nucleoside to prepare an RNAi preparation for extrahepatic delivery, and an RNAi preparation for extrahepatic delivery obtained thereby. The RNAi preparation can effectively deliver RNAi to extrahepatic tissue, such as muscle tissue, like skeletal muscle tissue and myocardial tissue, and adipose tissue.
2.WO/2026/098309POLYCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF
WO - 15.05.2026
Int.Class C07H 15/252
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
15Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
20Carbocyclic rings
24Condensed ring systems having three or more rings
252Naphthacene radicals, e.g. daunomycins, adriamycins
 Appl.No PCT/CN2025/131079 Applicant SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. Inventor TIAN, Qiang
The present invention relates to the field of medical biology, and in particular to a polycyclic compound, and a preparation method therefor and a use thereof. Specifically, the present invention relates to a compound, or a pharmaceutically acceptable salt, ester, stereoisomer, polymorph, solvate, nitrogen oxide, isotope marker, metabolite or prodrug thereof, such as a compound of formula (I'), or a pharmaceutical composition thereof, and a preparation method therefor and a use thereof. The compound can be used as a drug for treating diseases related to abnormal cell proliferation.
3.WO/2026/098623OLIGOSACCHARIDE-BASED MULTIFUNCTIONAL PLANT IMMUNOMODULATOR
WO - 15.05.2026
Int.Class C07H 15/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
15Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
02Acyclic radicals, not substituted by cyclic structures
04attached to an oxygen atom of a saccharide radical
 Appl.No PCT/CN2025/133371 Applicant SHANGHAI NOVAGLYCO BIOCHEMISTRY CO., LTD. Inventor MA, Yuyong
Provided in the present invention is an oligosaccharide-based multifunctional plant immunomodulator. Specifically, the plant immunomodulator has a structure represented by formula I below. The plant immunomodulator of the present invention can not only regulate the growth and development of crops, but also induce crops to resist against biological stress and abiotic stress, thereby improving the yield and quality of crops. By using the plant immunomodulator of the present invention, not only can multiple plant growth and development processes be positively regulated, including promoting seed germination, seedling morphogenesis and plant vigor at the mature stage, thereby increasing the crop yield and fruit quality, but also improving the resistance of plants against biological stress (diseases, insects and weeds) and abiotic stress (a frozen or near-frozen soil environment, drought, waterlogging, salinity and alkalinity, extremely low/high temperature, etc.). In addition, the plant immunomodulator of the present invention has the advantages of being non-toxic, free of pesticide residues, environmentally friendly, incapable of inducing pesticide resistance in pathogens, etc.
4.WO/2026/097180CMD LINKERS FOR LABEL-FREE MOLECULAR ANALYSIS, METHODS OF USE AND MANUFACTURE
WO - 15.05.2026
Int.Class G01N 33/543
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
543with an insoluble carrier for immobilising immunochemicals
 Appl.No PCT/CA2025/051493 Applicant NICOYA LIFESCIENCES INC. Inventor SEYED JAMALI, Hojjat
Disclosed herein are compositions, sensors, and kits for a carboxymethyl dextran (CMD) based linker for label-free molecular analysis. Further disclosed are methods for synthesizing a CMD-based linker for label-free molecular analysis and method for using reagent kits to immobilize a ligand on a sensor including a CMD-based linker for label-free molecular analysis.
5.WO/2026/099414METHOD FOR PRODUCING GOS SYRUP
WO - 15.05.2026
Int.Class C12P 19/04
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
19Preparation of compounds containing saccharide radicals
04Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
 Appl.No PCT/EP2025/082248 Applicant NOVOZYMES A/S Inventor TAMS, Jeppe Wegener
The present invention relates to isolated polypeptides having lactase activity which is beta-galactosidase activity (EC 3.2.1.108, 3.2.1.23) which show residual activity after ultra high temperature treatment of milk after which the activity increases during incubation at 23°C due to refolding and also relates to polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. Further, the invention relates to a method of producing galacto-oligosaccharides GOS applying the lactases of the invention.
6.WO/2026/099473OLIGONUCLEOTIDES WITH NEW INTERNUCLEOSIDE LINKAGE
WO - 15.05.2026
Int.Class C07H 21/02
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
21Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
02with ribosyl as saccharide radical
 Appl.No PCT/EP2025/082436 Applicant VICO THERAPEUTICS B.V. Inventor FRANKEN, Dennis Christian
The current invention provides an improved oligonucleotide and its use for treating, ameliorating, preventing, delaying and/or treating a human genetic disorder, said oligonucleotide comprising an internucleoside linkage of the following formula (I).
7.WO/2026/101887NUCLEOTIDES WITH ALPHA-IMINO PHOSPHATE GROUPS AND BRIDGING SULFURS, AND METHODS OF SYNTHESIZING AND USING THE SAME
WO - 15.05.2026
Int.Class C07H 19/10
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
19Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro derivatives thereof
02sharing nitrogen
04Heterocyclic radicals containing only nitrogen as ring hetero atom
06Pyrimidine radicals
10with the saccharide radical being esterified by phosphoric or polyphosphoric acids
 Appl.No PCT/US2025/053934 Applicant ILLUMINA, INC. Inventor RICHARD, Jean-Alexandre
Nucleotides with alpha-imino phosphate groups and bridging sulfurs, and methods of synthesizing and using the same, are provided herein. In some examples, a nucleotide may include a sugar, a nucleobase coupled to the sugar, an alpha-imino phosphate group, and a bridging sulfur coupling the alpha-imino phosphate group to the sugar.
8.WO/2026/098931PROCESS FOR MAKING AN ALKYL POLYGLYCOSIDE
WO - 15.05.2026
Int.Class C07H 1/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
1Processes for the preparation of sugar derivatives
 Appl.No PCT/EP2025/080001 Applicant BASF SE Inventor BIANGA, Stefan
-alcohol at a pressure in the range from 1 to 20 mbar at a temperature from 140 to 200 °C.
9.WO/2026/101930PHOSPHOGLYCOLIPIDS AND THEIR DERIVATIVES
WO - 15.05.2026
Int.Class A61K 31/70
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
 Appl.No PCT/US2025/054039 Applicant GLYCOSURF, INC. Inventor STOLLEY, Ryan
Described herein are phosphoglycolipids having a saccharide moiety attached at the 3-position of a phospholipid chain ("3-hydroxy phosphoglycolipids") and derivatives thereof. Also provided are methods for the synthesis of 3-hydroxy phosphoglycolipids and their derivatives.
10.WO/2026/099334SELF-ELIMINATING CLEAVABLE LINKERS
WO - 15.05.2026
Int.Class C07H 19/10
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
19Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro derivatives thereof
02sharing nitrogen
04Heterocyclic radicals containing only nitrogen as ring hetero atom
06Pyrimidine radicals
10with the saccharide radical being esterified by phosphoric or polyphosphoric acids
 Appl.No PCT/EP2025/082081 Applicant MILTENYI BIOTEC B.V. & CO. KG Inventor PINARD, Robert
The invention is directed to self-eliminating cleavable conjugates according to general formula (I) or (II) wherein AR is capable of an elimination reaction upon cleavage of CL.
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