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1. (US20180137930) Method and system for microbiome-derived characterization, diagnostics, and therapeutics for cardiovascular disease conditions

Office : United States of America
Application Number: 15848779 Application Date: 20.12.2017
Publication Number: 20180137930 Publication Date: 17.05.2018
Grant Number: 10347367 Grant Date: 09.07.2019
Publication Kind : B2
IPC:
G01N 33/48
G16H 10/40
C12Q 1/6883
G06F 19/00
G16B 40/00
G16B 50/00
G16H 50/20
H01L 27/32
H01L 51/00
H01L 51/52
G06G 7/58
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
[IPC code unknown for G16H 10/40][IPC code unknown for C12Q 1/6883]
G PHYSICS
06
COMPUTING; CALCULATING; COUNTING
F
ELECTRIC DIGITAL DATA PROCESSING
19
Digital computing or data processing equipment or methods, specially adapted for specific applications
[IPC code unknown for G16B 40][IPC code unknown for G16B 50][IPC code unknown for G16H 50/20]
H ELECTRICITY
01
BASIC ELECTRIC ELEMENTS
L
SEMICONDUCTOR DEVICES; ELECTRIC SOLID STATE DEVICES NOT OTHERWISE PROVIDED FOR
27
Devices consisting of a plurality of semiconductor or other solid-state components formed in or on a common substrate
28
including components using organic materials as the active part, or using a combination of organic materials with other materials as the active part
32
with components specially adapted for light emission, e.g. flat-panel displays using organic light-emitting diodes
H ELECTRICITY
01
BASIC ELECTRIC ELEMENTS
L
SEMICONDUCTOR DEVICES; ELECTRIC SOLID STATE DEVICES NOT OTHERWISE PROVIDED FOR
51
Solid state devices using organic materials as the active part, or using a combination of organic materials with other materials as the active part; Processes or apparatus specially adapted for the manufacture or treatment of such devices, or of parts thereof
H ELECTRICITY
01
BASIC ELECTRIC ELEMENTS
L
SEMICONDUCTOR DEVICES; ELECTRIC SOLID STATE DEVICES NOT OTHERWISE PROVIDED FOR
51
Solid state devices using organic materials as the active part, or using a combination of organic materials with other materials as the active part; Processes or apparatus specially adapted for the manufacture or treatment of such devices, or of parts thereof
50
specially adapted for light emission, e.g. organic light emitting diodes (OLED) or polymer light emitting devices (PLED)
52
Details of devices
G PHYSICS
06
COMPUTING; CALCULATING; COUNTING
G
ANALOGUE COMPUTERS
7
Devices in which the computing operation is performed by varying electric or magnetic quantities
48
Analogue computers for specific processes, systems, or devices, e.g. simulators
58
for chemical processes
CPC:
C12Q 1/6883
G16H 10/40
G06F 19/3418
G16B 40/00
G16B 50/00
G16H 50/20
H01L 27/3211
H01L 27/3272
H01L 51/0097
H01L 51/5234
H01L 51/5265
H01L 51/5281
H01L 51/5284
C12Q 2600/112
G01N 2800/044
G01N 2800/32
H01L 27/322
H01L 2251/5338
Y02A 90/26
Applicants: uBiome, Inc.
Inventors: Zachary Apte
Daniel Almonacid
Jessica Richman
Agents: Kilpatrick Townsend & Stockton LLP
Priority Data:
Title: (EN) Method and system for microbiome-derived characterization, diagnostics, and therapeutics for cardiovascular disease conditions
Abstract: front page image
(EN)

A method for at least one of characterizing, diagnosing, and treating a cardiovascular disease condition in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the cardiovascular disease condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the cardiovascular disease condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.