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1. US20140113915 - NOVEL PYRIDOPYRIMIDINE DERIVATIVES AND USE THEREOF

Office United States of America
Application Number 14137158
Application Date 20.12.2013
Publication Number 20140113915
Publication Date 24.04.2014
Publication Kind A1
IPC
C07D 471/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
471Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/-C07D463/251
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
CPC
C07D 471/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
471Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
Applicants The Asan Foundation
Inventors Lee Gilnam
Lim Chul Soo
Cho Han Won
Seo Jeongbeob
Gyorkos Albert C.
Cho Suk Young
Choi Eun Kyung
Kim Choung Soo
Hwang Jung Jin
Title
(EN) NOVEL PYRIDOPYRIMIDINE DERIVATIVES AND USE THEREOF
Abstract
(EN)

The invention provides novel substituted pyridopyrimidines represented by Formula I or a pharmaceutically acceptable salt, solvate, polymorph, ester, tautomer or prodrug thereof, and a composition comprising these compounds. The compounds provided can be used as inhibitors of the phosphoinositide 3′ OH kinase family (PI3K) for the treatment of inflammatory diseases, cancer, cardiovascular diseases, allergy, asthma and autoimmune disorders.

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