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1. (US20030194405) Antibody to stem cell factor

Office : United States of America
Application Number: 10320231 Application Date: 16.12.2002
Publication Number: 20030194405 Publication Date: 16.10.2003
Grant Number: 7285640 Grant Date: 23.10.2007
Publication Kind : B2
IPC:
C07K 16/00
C07K 16/22
G01N 33/564
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
22
against growth factors
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
564
for pre-existing immune complex or autoimmune disease
CPC:
G01N 33/564
A61K 2039/505
C07K 16/22
C07K 2317/21
C07K 2317/55
C07K 2317/565
C07K 2317/622
C07K 2317/73
Applicants: Bayer Corporation
Inventors: Takeuchi Toshihiko
Tomkinson Adrian
Neben Steven
Agents: DLA Piper US LLP
Priority Data: 10320231 16.12.2002 US
60342174 17.12.2001 US
Title: (EN) Antibody to stem cell factor
Abstract: front page image
(EN)

The present invention provides human antibodies specific for stem cell factor that contain at least one CDR derived from a combinatorial antibody library. The invention also provides pharmaceutical compositions comprising the antibodies and methods of treating asthma. The invention further provides methods of detecting stem cell factor using the antibodies.