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1. EP3307437 - MANUAL OR ELECTRONIC PIPETTE DRIVEN WELL PLATE FOR NANO-LITER DROPLET STORAGE AND METHODS OF USING SAME

Office European Patent Office
Application Number 16808519
Application Date 13.06.2016
Publication Number 3307437
Publication Date 18.04.2018
Publication Kind A4
IPC
B01L 3/00
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
3Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
F16K 99/00
FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
16ENGINEERING ELEMENTS OR UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
KVALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
99Subject matter not provided for in other groups of this subclass
G01N 1/10
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
1Sampling; Preparing specimens for investigation
02Devices for withdrawing samples
10in the liquid or fluent state
G01N 1/28
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
1Sampling; Preparing specimens for investigation
28Preparing specimens for investigation
G01N 1/38
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
1Sampling; Preparing specimens for investigation
28Preparing specimens for investigation
38Diluting, dispersing or mixing samples
CPC
B01L 3/502738
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
3Containers or dishes for laboratory use, e.g. laboratory glassware
50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
502with fluid transport, e.g. in multi-compartment structures
5027by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
502738characterised by integrated valves
B01L 3/502746
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
3Containers or dishes for laboratory use, e.g. laboratory glassware
50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
502with fluid transport, e.g. in multi-compartment structures
5027by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
502746characterised by the means for controlling flow resistance, e.g. flow controllers, baffles
B01L 2200/0605
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2200Solutions for specific problems relating to chemical or physical laboratory apparatus
06Fluid handling related problems
0605Metering of fluids
B01L 2200/0673
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2200Solutions for specific problems relating to chemical or physical laboratory apparatus
06Fluid handling related problems
0673Handling of plugs of fluid surrounded by immiscible fluid
B01L 2300/0829
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2300Additional constructional details
08Geometry, shape and general structure
0809rectangular shaped
0829Multi-well plates; Microtitration plates
B01L 2300/087
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2300Additional constructional details
08Geometry, shape and general structure
0861Configuration of multiple channels and/or chambers in a single devices
087Multiple sequential chambers
Applicants NEOFLUIDICS LLC
Inventors SOLOMON DEEPAK
Designated States
Priority Data 201562174310 11.06.2015 US
2016037225 13.06.2016 US
Title
(DE) MANUELLE ODER ELEKTRONISCHE PIPETTENBETRIEBENE MIKROTITERPLATTE FÜR NANOLITERTRÖPFCHENLAGERUNG UND VERFAHREN ZUR VERWENDUNG DAVON
(EN) MANUAL OR ELECTRONIC PIPETTE DRIVEN WELL PLATE FOR NANO-LITER DROPLET STORAGE AND METHODS OF USING SAME
(FR) PLAQUE DE PUITS ENTRAÎNÉE PAR PIPETTE MANUELLE OU ÉLECTRONIQUE POUR LE STOCKAGE DE NANO-LITRES DE GOUTTELETTES ET PROCÉDÉS D'UTILISATION ASSOCIÉS
Abstract
(EN)
Described herein are pipette driven well plates for nano-liter droplet storage and methods of using same. Embodiments may include an inlet, an outlet, a bypass channel, and a fluidic trap containing a valve covered by a removable covering, in which the fluid enters the fluidic trap when the removable covering is removed. The fluid enters either the fluidic trap or the bypass channel, depending on which of the fluidic trap or bypass channel has the lower hydrodynamic resistance. Embodiments may be used by closing the valve, introducing a first fluid to fill the fluidic trap and partially fill a bypass channel, opening the valve, removing the first fluid surrounding the valve, and introducing a second fluid into the fluidic trap, in which the introducing results in a mixture of the first and second fluids.

(FR)
L'invention concerne des plaques de puits entraînées par pipette pour le stockage de nano-litres de gouttelettes et des procédés d'utilisation associés. Des modes de réalisation peuvent comprendre une admission, une évacuation, un canal de dérivation et un piège fluidique contenant une soupape recouverte par une enveloppe amovible, le fluide pénétrant dans le piège fluidique lorsque l'enveloppe amovible est retirée. Le fluide pénètre soit dans le piège fluidique soit dans le canal de dérivation, en fonction de quel élément parmi le piège fluidique et le canal de dérivation présente la résistance hydrodynamique la plus faible. Des modes de réalisation peuvent être utilisés en fermant la soupape, en introduisant un premier fluide pour remplir le piège fluidique et remplir partiellement un canal de dérivation, en ouvrant la soupape, en retirant le premier fluide entourant la soupape et en introduisant un second fluide dans le piège fluidique, l'introduction résultant en un mélange des premier et second fluides.

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