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1. (EP3283084) METHOD AND SYSTEM FOR MICROBIOME-DERIVED CHARACTERIZATION, DIAGNOSTICS AND THERAPEUTICS FOR CUTANEOUS CONDITIONS

Office : European Patent Office
Application Number: 16780667 Application Date: 13.04.2016
Publication Number: 3283084 Publication Date: 21.02.2018
Publication Kind : A4
Prior PCT appl.: Application Number:US2016027355 ; Publication Number: Click to see the data
IPC:
A61K 35/74
A61K 35/741
A61P 1/00
G06F 19/12
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35
Medicinal preparations containing material or reaction products thereof with undetermined constitution
66
Materials from micro-organisms
74
Bacteria
[IPC code unknown for A61K 35/741]
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1
Drugs for disorders of the alimentary tract or the digestive system
G PHYSICS
06
COMPUTING; CALCULATING; COUNTING
F
ELECTRIC DIGITAL DATA PROCESSING
19
Digital computing or data processing equipment or methods, specially adapted for specific applications
10
Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology
12
for modelling or simulation in systems biology, e.g. probabilistic or dynamic models, gene-regulatory networks, protein interaction networks or metabolic networks
CPC:
A61K 35/74
A61K 35/741
G16B 20/00
Applicants: UBIOME INC
Inventors: APTE ZACHARY
ALMONACID DANIEL
RICHMAN JESSICA
BEHBAHANI SIAVOSH REZVAN
Priority Data: 201562146789 13.04.2015 US
201562147083 14.04.2015 US
2016027355 13.04.2016 US
Title: (DE) VERFAHREN UND SYSTEM ZUR MIKROBIOMDERIVIERTEN CHARAKTERISIERUNG, DIAGNOSTIKA UND THERAPEUTIKA FÜR HAUTERKRANKUNGEN
(EN) METHOD AND SYSTEM FOR MICROBIOME-DERIVED CHARACTERIZATION, DIAGNOSTICS AND THERAPEUTICS FOR CUTANEOUS CONDITIONS
(FR) PROCÉDÉ ET SYSTÈME DE CARACTÉRISATION, DE DIAGNOSTICS ET DE TRAITEMENTS DÉRIVÉS DU MICROBIOME POUR DES DERMATOSES
Abstract:
(EN) A method for at least one of characterizing, diagnosing, and treating a cutaneous condition in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the cutaneous condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the cutaneous condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
(FR) L'invention concerne un procédé destiné à la caractérisation et/ou au diagnostic et/ou au traitement d'une dermatose chez au moins un patient, le procédé comprenant les étapes consistant : à recevoir un ensemble agrégé d'échantillons biologiques provenant d'une population de patients ; générer un ensemble de données concernant la composition du microbiome et/ou un ensemble de données concernant la diversité fonctionnelle du microbiome pour la population de patients ; caractériser la dermatose sur la base des caractéristiques extraites de l'ensemble de données sur la composition du microbiome et/ou de l'ensemble de données sur la diversité fonctionnelle du microbiome ; générer, sur la base de cette caractérisation, un modèle thérapeutique conçu pour corriger la dermatose ; et promouvoir auprès du patient, sur un dispositif de sortie qui lui est associé, un traitement sur la base de la caractérisation et du modèle thérapeutique.