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1. (CN107849616) METHOD AND SYSTEM FOR MICROBIOME-DERIVED CHARACTERIZATION, DIAGANOSTICS AND THERAPEUTICS FOR CONDITIONS ASSOCIATED WITH FUNCTIONAL FEATURES

Office : China
Application Number: 201680034379.5 Application Date: 13.04.2016
Publication Number: 107849616 Publication Date: 27.03.2018
Publication Kind : A
Prior PCT appl.: Application Number:PCTUS2016027349 ; Publication Number: Click to see the data
IPC:
C12Q 1/689
C12Q 1/6895
G01N 33/48
G01N 33/569
[IPC code unknown for C12Q 1/689][IPC code unknown for C12Q 1/6895]
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
569
for micro-organisms, e.g. protozoa, bacteria, viruses
Applicants: UBIOME INC
优比欧迈公司
Inventors: APTE ZACHARY
扎迦利·阿普特
ALMONACID DANIEL
丹尼尔·阿尔莫纳西德
RICHMAN JESSICA
杰西卡·里奇曼
BEHBAHANI SIAVOSH REZVAN
斯亚沃什·瑞兹万·贝赫巴哈尼
Agents: 北京安信方达知识产权代理有限公司 11262
北京安信方达知识产权代理有限公司 11262
Priority Data: 62/146,818 13.04.2015 US
62/147,096 14.04.2015 US
62/147,334 14.04.2015 US
Title: (EN) METHOD AND SYSTEM FOR MICROBIOME-DERIVED CHARACTERIZATION, DIAGANOSTICS AND THERAPEUTICS FOR CONDITIONS ASSOCIATED WITH FUNCTIONAL FEATURES
(ZH) 用于功能特征相关的状况的微生物组来源的表征、诊断和治疗的方法及系统
Abstract: front page image
(EN) A method for at least one of characterizing, diagnosing, and treating a condition associated with microbiome-derived functional features in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects;generating a characterization of the condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterizationand the therapy model.
(ZH) 一种用于至少一个受试者中的微生物组来源的功能特征相关的状况的表征、诊断和治疗中的至少一种的方法,该方法包括:接收来自受试者群体的生物样品的聚合集;生成受试者群体的微生物组组成数据集和微生物组功能多样性数据集中的至少一种;基于从微生物组组成数据集和微生物组功能多样性数据集中的至少一种提取的特征生成状况的表征;基于该表征生成被配置为矫正状况的疗法模型;以及在与受试者相关联的输出设备,基于表征和疗法模型为受试者安排疗法。