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1. (CN107708716) Method and system for microbiome-derived diagnostics and therapeutics for conditions associated with microbiome taxonomic features

Office : China
Application Number: 201680034679.3 Application Date: 13.04.2016
Publication Number: 107708716 Publication Date: 16.02.2018
Publication Kind : A
Prior PCT appl.: Application Number:PCTUS2016027357 ; Publication Number: Click to see the data
IPC:
A61K 35/74
A61K 35/741
A61P 1/00
G06F 19/12
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35
Medicinal preparations containing material or reaction products thereof with undetermined constitution
66
Materials from micro-organisms
74
Bacteria
[IPC code unknown for A61K 35/741]
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1
Drugs for disorders of the alimentary tract or the digestive system
G PHYSICS
06
COMPUTING; CALCULATING; COUNTING
F
ELECTRIC DIGITAL DATA PROCESSING
19
Digital computing or data processing equipment or methods, specially adapted for specific applications
10
Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology
12
for modelling or simulation in systems biology, e.g. probabilistic or dynamic models, gene-regulatory networks, protein interaction networks or metabolic networks
Applicants: UBIOME, INC.
Inventors: APTE ZACHARY
ALMONACID DANIEL
RICHMAN JESSICA
BEHBAHANI SIAVOSH REZVAN
Priority Data: 62/146,767 13.04.2015 US
62/146,833 13.04.2015 US
62/147,077 14.04.2015 US
62/147,304 14.04.2015 US
Title: (EN) Method and system for microbiome-derived diagnostics and therapeutics for conditions associated with microbiome taxonomic features
(ZH) 用于微生物组分类学特征相关的状况的微生物组来源的诊断和治疗的方法及系统
Abstract: front page image
(EN) A method for at least one of characterizing, diagnosing, and treating a condition associated with microbiome taxonomic features in at least a subject, the method comprising: receiving an aggregate setof biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
(ZH) 一种用于至少一个受试者中的微生物组分类学特征相关的状况的表征、诊断和治疗中的至少一种的方法,该方法包括:接收来自受试者群体的生物样品的聚合集;生成受试者群体的微生物组组成数据集和微生物组功能多样性数据集中的至少一种;基于从微生物组组成数据集和微生物组功能多样性数据集中的至少一种提取的特征生成状况的表征;基于该表征生成被配置为矫正状况的疗法模型;以及在与受试者相关联的输出设备,基于表征和疗法模型为受试者安排疗法。