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1. (ZA2005/06611) THIENOPYRAMIDINE COMPOUNDS AND USE THEREOF

Office : South Africa
Application Number: 2005/06611 Application Date: 18.08.2005
Publication Number: 2005/06611 Publication Date: 27.12.2006
Publication Kind : B
Prior PCT appl.: Application Number:PCTJP04000741 ; Publication Number:04067535 Click to see the data
IPC:
A 61
C 07
A 61
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
Applicants: TAKEDA PHARMACEUTICAL COMPANY LIMITED
Inventors: CHO NOBUO
IMADA TAKASHI
HITAKA TAKENORI
MIWA KAZUHIRO
KUSAKA MASAMI
SUZUKI NOBUHIRO
Agents: SPOOR & FISHER
Priority Data: 2003/020854 null JP
2003/020854 29.01.2003 JP
Title: (EN) THIENOPYRAMIDINE COMPOUNDS AND USE THEREOF
Abstract:
(EN) It is intended to provide a compound represented by the following general formula or its salt: wherein R1 represents C -4 alkyl; R2 represents (1 ) a nitrogen-containing 5- to 7-membered heterocyclic group optionally having a substituent selected from among (1 ') halogeno, (2') hydroxy, (3') C alkyl and (4') C1-4 alkoxy, (2) phenyl optionally having a substituent selected from among (V) halogeno, (2') Ci^ alkoxy-Ci^ alkyl, (3') mono alkyl-carbamoyl-C^ alkyl, (4') Ci-4 alkoxy and (5') mono alkylcarbamoyl-C^ alkoxy, etc.; R3 represents C - alkyl; R4 represents alkoxy, etc.; and n is an integer of from 1 to 4; as a thienopyrimidine compound having antagonism to gonadotropin-releasing hormone.
Also published as:
NO20053974PL378002PLP.378002MXPA/a/2005/007990KR1020050096171IL169869
BRPI0407082CO5590921EP1591446JP2004250439JP2008094846RU02331648
US20060160829US20080108623US20120071486CN1768065CA2514407ES2410814
US20140221381PT1591446NZ541772DK1591446AU2004207706BNRE/2013/0034
ID047.1556BRPI0407082WO/2004/067535